{"product_id":"sulfamethoxazole-trimethoprim-tablets-800-mg-60-mg","title":"SMZ\/TMP (sulfamethoxazole and trimethoprim) Tablets, 800 mg\/160 mg","description":"\u003ch2\u003eBroad-Spectrum Sulfonamide Antibiotic Tablets for Dogs and Cats\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eSulfamethoxazole and Trimethoprim 800mg\/160mg Tablets are a prescription double-strength combination antibiotic that veterinarians use for bacterial and protozoal infections across multiple body systems in dogs, cats, and horses. The two active ingredients target separate stages of bacterial replication, working together to produce an effect stronger than either could achieve alone. These scored tablets cover respiratory, urinary, skin, gastrointestinal, ear infections, kennel cough, and coccidiosis.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergistic Dual Mechanism:\u003c\/strong\u003e Sulfamethoxazole and trimethoprim target two separate steps in bacterial DNA synthesis, producing stronger combined bactericidal action than either alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Tract Infection Treatment:\u003c\/strong\u003e Treats bacterial urinary tract and kidney infections in dogs and cats caused by a broad range of susceptible organisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRespiratory Infection Coverage:\u003c\/strong\u003e Used to treat respiratory infections including pneumonia and kennel cough caused by susceptible bacteria in dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtozoal Infection Treatment:\u003c\/strong\u003e Effective against coccidiosis and other protozoal infections in dogs and cats alongside its broad bacterial coverage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin and GI Infection Coverage:\u003c\/strong\u003e Treats skin infections and gastrointestinal bacterial infections in dogs and cats under veterinary supervision.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSulfamethoxazole 800mg, Trimethoprim 160mg\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eSulfamethoxazole and Trimethoprim 800mg\/160mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking it inside a soft pill pocket or wrapping it in a pill wrap treat is one of the easiest ways to make the whole process stress-free.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/collections\/dog-pill-pockets\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/collections\/cat-pill-pockets\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eProvide Plenty of Fresh Water:\u003c\/strong\u003e Fresh water must always be available throughout the course, as good hydration helps protect the urinary tract during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Sulfonamide Allergy:\u003c\/strong\u003e Never use in animals with a known sensitivity to sulfonamide drugs, as serious allergic reactions can occur.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Liver and Kidney Disease:\u003c\/strong\u003e Impaired organ function significantly raises the risk of toxicity in pets given this medication during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Blood Disorders:\u003c\/strong\u003e Pets with known blood-related disorders should not receive this medication, as bone marrow suppression can occur.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant or Nursing Animals:\u003c\/strong\u003e Potential effects on developing offspring mean this medication must be avoided in pregnant or lactating animals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKCS Risk in Dogs:\u003c\/strong\u003e Watch for redness, discharge, and reduced tear production in dogs on longer treatment courses involving this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck for Drug Interactions:\u003c\/strong\u003e Your vet needs a full picture of every medication your pet is currently on before SMZ\/TMP is started.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting and Reduced Appetite in Dogs:\u003c\/strong\u003e Loss of appetite and vomiting are the most commonly reported digestive side effects in dogs receiving this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Salivation in Cats:\u003c\/strong\u003e Cats may develop noticeable salivation after administration, which is a commonly reported species-specific reaction to this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDry Eye Syndrome:\u003c\/strong\u003e Dogs on extended courses may develop reduced tear production, with redness and discharge around the eyes worth flagging to your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone Marrow Suppression:\u003c\/strong\u003e Routine blood count checks are a sensible precaution for pets receiving this medication over a prolonged period of time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Allergic Reactions:\u003c\/strong\u003e Facial swelling, hives, breathing trouble, or sudden collapse are signs needing emergency veterinary care straight away.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store tablets in a tightly closed container away from heat and humidity, keeping conditions stable and consistent between doses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect from Moisture and Light:\u003c\/strong\u003e A dark, dry storage location away from direct sunlight is the best way to keep these tablets at their full strength.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Always store this medication somewhere secure and out of reach of children and untreated pets.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNote: \u003c\/strong\u003e\u003c\/span\u003eFor generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What infections does sulfamethoxazole and trimethoprim treat in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SMZ\/TMP covers a notably broad range of infections in dogs and cats, from urinary and respiratory conditions through to skin, gastrointestinal, ear, and protozoal infections like coccidiosis. Its dual-mechanism action gives it reach against organisms that single-agent antibiotics sometimes miss. Your vet will confirm susceptibility before prescribing it for your pet's specific infection.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why must pets drink plenty of water when taking sulfamethoxazole and trimethoprim?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This antibiotic has a tendency to form crystals in the urinary tract if urine becomes too concentrated during treatment. Keeping your pet well hydrated throughout the course helps dilute the urine enough to stop that from happening and protects the kidneys and bladder from irritation. Your vet may flag this specifically if your pet is not a big drinker naturally.\u003c\/p\u003e\n\u003ch3\u003eQ3: Can SMZ\/TMP cause dry eye in dogs and how would I recognise it?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In dogs on longer courses of this medication, the tear glands can gradually produce less fluid, leaving the eyes dry, red, and prone to discharge. The cornea may also start to look dull or hazy if things progress. Any changes around your dog's eyes during or after a course of SMZ\/TMP are worth raising with your vet sooner rather than later.\u003c\/p\u003e\n\u003ch3\u003eQ4: Is sulfamethoxazole and trimethoprim FDA-approved for use in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e SMZ\/TMP is FDA-approved for use in people, not in companion animals. Vets prescribe it for dogs, cats, and horses on an off-label basis when it is the most appropriate option for the condition being treated and no suitable veterinary-approved alternative is available. This is a standard and well-established practice in veterinary medicine.\u003c\/p\u003e\n\u003ch3\u003eQ5: Why should SMZ\/TMP not be given to pets with liver or kidney disease?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both components of this medication rely on healthy kidney and liver function to be processed and cleared from the body at a safe rate. When either organ is not working properly, the medication can build up to levels that put the animal at real risk of serious harm. Always give your vet a full picture of your pet's health before starting any course of this antibiotic.\u003c\/p\u003e\n\u003ch2\u003eClinical Research:\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a684026.html\" title=\"Co-trimoxazole: medlineplus drug information\" aria-label=\"Visit a webpage about Co-trimoxazole: medlineplus drug information\"\u003e\u003cspan\u003eMedlinePlus\u003c\/span\u003e\u003cspan\u003e - Sulfamethoxazole\u003c\/span\u003e\u003cspan\u003e and\u003c\/span\u003e\u003cspan\u003e Trimethoprim\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/emedicine.medscape.com\/article\/768875-medication?form=fpf\" title=\"Medscape - sulfamethoxazole and trimethoprim overview\" aria-label=\"Visit a webpage about Medscape - sulfamethoxazole and trimethoprim overview\"\u003e\u003cspan\u003eMedscape\u003c\/span\u003e\u003cspan\u003e - Sulfamethoxazole\u003c\/span\u003e\u003cspan\u003e and\u003c\/span\u003e\u003cspan\u003e Trimethoprim\u003c\/span\u003e\u003cspan\u003e Overview\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.dhs.wisconsin.gov\/publications\/p03601d.pdf\" title=\"Wisconsin department of health services - sulfamethoxazole and trimethoprim fact sheet\" aria-label=\"Visit a webpage about Wisconsin department of health services - sulfamethoxazole and trimethoprim fact sheet\"\u003e\u003cspan\u003eWisconsin\u003c\/span\u003e\u003cspan\u003e Department\u003c\/span\u003e\u003cspan\u003e of\u003c\/span\u003e\u003cspan\u003e Health\u003c\/span\u003e\u003cspan\u003e Services\u003c\/span\u003e\u003cspan\u003e - Sulfamethoxazole\u003c\/span\u003e\u003cspan\u003e and\u003c\/span\u003e\u003cspan\u003e Trimethoprim\u003c\/span\u003e\u003cspan\u003e Fact\u003c\/span\u003e\u003cspan\u003e Sheet\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 tablet","offer_id":41817302040737,"sku":"258212-1","price":0.15,"currency_code":"USD","in_stock":true},{"title":"30 tablets","offer_id":44422606094497,"sku":"258212-30","price":4.5,"currency_code":"USD","in_stock":true},{"title":"60 tablets","offer_id":44422606127265,"sku":"258212-60","price":8.95,"currency_code":"USD","in_stock":true},{"title":"100 tablets","offer_id":41817302007969,"sku":"258212-100","price":11.99,"currency_code":"USD","in_stock":true},{"title":"500 tablets","offer_id":41817301975201,"sku":"258212","price":52.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/smz-tmp-sulfamethoxazole-and-trimethoprim-tablets-800-mg-160-mg-pet-875.png?v=1777915030","url":"https:\/\/hordypaw.shop\/products\/sulfamethoxazole-trimethoprim-tablets-800-mg-60-mg","provider":"HardyPaw","version":"1.0","type":"link"}