{"product_id":"simparica-flea-tick-chewables-medium-dogs-green-box","title":"Simparica for Dogs 22.1-44 lbs","description":"\u003ch2\u003eSimparica 40mg Monthly Chewable for Flea and Tick Control in Medium Dogs\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eSimparica (sarolaner) 40 mg is a prescription-strength, pork liver-flavored monthly chewable tablet designed for medium-sized dogs weighing 22.1 to 44 lbs. Its active ingredient, sarolaner, targets the nervous system of fleas and ticks by blocking GABA and glutamate receptors, causing paralysis and death in parasites. It begins killing fleas within 3 hours and ticks within 8 hours, offering dependable 35-day protection.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKills Fleas Within Hours:\u003c\/strong\u003e One oral dose gets to work fast, with adult fleas dying off within 3 hours and ticks within 8 hours.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eUninterrupted Monthly Coverage:\u003c\/strong\u003e Each dose keeps flea and tick protection going strong and steady for a full 35 days without any drop-off.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eControls Six Tick Species:\u003c\/strong\u003e A single monthly chew covers Lone Star, Gulf Coast, American Dog, Black-legged, Brown Dog, and Asian Longhorned ticks.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLyme Disease Prevention:\u003c\/strong\u003e FDA-approved to help prevent Borrelia burgdorferi infections by killing deer ticks before disease transmission can occur.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBreaks the Flea Life Cycle:\u003c\/strong\u003e Works at the source by stopping adult fleas from ever reaching the egg-laying stage, clearing active infestations and keeping fresh ones from gaining ground.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRelieves Flea Allergy Symptoms:\u003c\/strong\u003e Helps reduce dermatitis-related signs such as erythema, papules, alopecia, and pruritus caused directly by flea infestations.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eWeight-Specific Blue Pack:\u003c\/strong\u003e The blue color-coded pack ensures accurate, safe dosing specifically calibrated for medium dogs in the 22.1 to 44 lb range.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSarolaner 40 mg per tablet\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Needed:\u003c\/strong\u003e Simparica is a federally restricted prescription medication; a valid veterinary prescription is required before dispensing or administering this product.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCorrect Dose for Medium Dogs:\u003c\/strong\u003e Give one 40 mg chewable tablet orally once every 28 to 30 days to dogs weighing between 22.1 and 44 lbs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMultiple Ways to Administer:\u003c\/strong\u003e The chew can be offered directly by hand, tucked into food, or given as a regular oral tablet based on what your dog accepts easily.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eConfirm Full Consumption:\u003c\/strong\u003e Monitor your dog for a few minutes after dosing to make sure the entire chewable tablet has been fully swallowed.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMissed Dose Management:\u003c\/strong\u003e If a monthly dose is skipped, give it as soon as you remember and then continue with the regular monthly dosing schedule.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eYear-Round Administration:\u003c\/strong\u003e Treatment can start at any time of year and should be continued monthly without interruption for consistent, reliable coverage.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTreat All Household Pets:\u003c\/strong\u003e For best results against re-infestation, treat all dogs and cats in the home with a vet-approved flea and tick control product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAge Restriction Applies:\u003c\/strong\u003e Simparica is only approved for dogs aged 6 months and older; it should not be administered to younger puppies under any circumstance.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNeurological History:\u003c\/strong\u003e Use with caution in any dog with a known history of seizures or neurological disorders, and only under direct veterinary supervision.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eReproductive Safety Unknown:\u003c\/strong\u003e The product has not been evaluated in breeding, pregnant, or nursing dogs; consult your veterinarian before use in these animals.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDogs Only:\u003c\/strong\u003e Simparica is strictly formulated for use in dogs and must never be given to cats or any other animal species.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSafe Storage is Essential:\u003c\/strong\u003e Keep the product in a secured location away from all pets to prevent accidental ingestion and potential overdose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eOut of Children's Reach:\u003c\/strong\u003e As with all veterinary medications, Simparica must always be stored where children cannot access it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e Most commonly observed adverse reaction in clinical trials; typically mild, short-lived, and not a cause for immediate concern.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose or bloody stools have been reported in a small number of dogs following monthly Simparica administration.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLethargy:\u003c\/strong\u003e A dog may show temporary low energy or reduced activity in the period following administration of a dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTremors and Ataxia:\u003c\/strong\u003e Neurological signs such as muscle tremors and unsteady movement have been reported; contact your vet right away if observed.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSeizures:\u003c\/strong\u003e Seizures have been reported in dogs on isoxazoline-class drugs, including those with no prior seizure history; veterinary attention is required immediately.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eReduced Appetite and Itching:\u003c\/strong\u003e Anorexia and pruritus are among the post-approval adverse events noted from owner and veterinary reports after Simparica use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eStore Below 30°C:\u003c\/strong\u003e Keep at or below 30°C (86°F); brief temperature excursions up to 40°C (104°F) are acceptable without compromising product integrity.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSecure from Pets:\u003c\/strong\u003e Store in a locked or inaccessible location away from all pets to prevent accidental self-administration or overdose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAway from Children:\u003c\/strong\u003e Always store Simparica and all pet medications in a place that is completely out of the reach of children.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" target=\"_blank\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" target=\"_blank\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What is Simparica Blue Pack 40mg used for in medium dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Simparica Blue Pack (40 mg) is a monthly prescription chewable that treats and prevents flea infestations and controls six tick species in medium dogs weighing 22.1 to 44 lbs. It is also FDA-approved to help prevent Lyme disease caused by deer tick bites.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: How does sarolaner in Simparica kill fleas and ticks on dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Sarolaner blocks GABA and glutamate neurotransmitter receptors in parasites, triggering uncontrolled neuromuscular activity that leads to paralysis and death. This mechanism acts through the dog's bloodstream when parasites feed, making it fast and highly effective.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: Is Simparica flea tablet safe to use throughout the year for medium dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. Simparica can be started at any time of year and should be given monthly without interruption for continuous coverage. In areas where fleas and ticks are active year-round, consistent monthly dosing is recommended to maintain complete protection for your dog.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: Does Simparica sarolaner chew help dogs suffering from flea allergy dermatitis?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. By killing fleas before they lay eggs and eliminating active infestations, Simparica has been shown to improve dermatitis-related signs like skin redness, hair loss, papules, and intense itching that are directly caused by flea allergy reactions in dogs.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: Why is weight-specific dosing important when choosing a Simparica pack for your dog?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Each Simparica pack is color-coded and calibrated to deliver the correct minimum dose of sarolaner per kilogram of body weight. Choosing the right pack, like the blue 40 mg for 22.1 to 44 lb dogs, ensures your dog receives safe, effective, and precisely targeted parasite protection every month.\u003c\/p\u003e\n\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.avma.org\/resources-tools\/pet-owners\/petcare\/flea-and-tick-control-pets\" target=\"_blank\" rel=\"noopener\" title=\"American veterinary medical association (avma) - flea and tick control in pets\" aria-label=\"Visit a webpage about American veterinary medical association (avma) - flea and tick control in pets\"\u003eAmerican Veterinary Medical Association (AVMA) - Flea and Tick Control in Pets\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.fda.gov\/animal-veterinary\/animal-health-literacy\/safe-use-isoxazoline-flea-and-tick-products\" target=\"_blank\"\u003eFDA - Safe Use of Isoxazoline Flea and Tick Products\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/capcvet.org\/guidelines\/tick-borne-diseases\/\" target=\"_blank\"\u003eCompanion Animal Parasite Council (CAPC) - Tick-Borne Diseases in Dogs\u003c\/a\u003e\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"1 Chewable Tablet (1 month supply)","offer_id":41244946759841,"sku":"10012454-1","price":27.93,"currency_code":"USD","in_stock":true},{"title":"3 Chewable Tablets (3 month supply)","offer_id":41244946825377,"sku":"10012454","price":76.97,"currency_code":"USD","in_stock":true},{"title":"6 Chewable Tablets (6 month supply)","offer_id":41244946792609,"sku":"10012460","price":139.63,"currency_code":"USD","in_stock":true},{"title":"12 Chewable Tablets (12 month supply)","offer_id":44135993639073,"sku":"10012460-PK2","price":279.26,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/simparica-for-dogs-22-1-44-lbs-3-chewable-tablets-3-month-supply-336.jpg?v=1778103530","url":"https:\/\/hordypaw.shop\/products\/simparica-flea-tick-chewables-medium-dogs-green-box","provider":"HardyPaw","version":"1.0","type":"link"}