{"product_id":"prascend-tablets-for-horses-1-mg","title":"Prascend Pergolide for Horses - 1 mg Tablets","description":"\u003ch2\u003e\u003cstrong\u003eControls PPID Symptoms in Horses\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003ePRASCEND is an FDA-approved oral tablet formulated for horses diagnosed with Pituitary Pars Intermedia Dysfunction, commonly known as Equine Cushing’s Disease. It contains pergolide mesylate, a dopamine receptor agonist that helps regulate hormone levels linked to PPID. Daily administration supports improvement in clinical signs such as hirsutism, abnormal fat distribution, and muscle wasting when used as directed by a veterinarian.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormone Level Regulation Aid:\u003c\/strong\u003e Designed to help bring elevated ACTH levels closer to normal in PPID affected horses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Symptom Management: \u003c\/strong\u003eHelps address long coats, excessive sweating, muscle thinning, and unusual fat deposits.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDocumented Treatment Results: \u003c\/strong\u003eProven effectiveness observed in more than three out of four horses by Day 180.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdaptable Dosage Approach:\u003c\/strong\u003e Dosage can be fine tuned based on lab results and the horse’s clinical response.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAvailable in 3 sizes: \u003c\/strong\u003e1 Tablet,  60 tablets, and 160 tablets.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eActive Ingredients\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003ePergolide mesylate 1 mg per tablet\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable height=\"122\" style=\"width: 73.5714%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e\u003cstrong\u003eBody Weight\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2 mcg per kg\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4 mcg per kg\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e136 to 340 kg (300 to 749 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e0.5 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e341 to 567 kg (750 to 1,249 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e2 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e568 to 795 kg (1,250 to 1,749 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e1.5 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e3 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e796 to 1,022 kg (1,750 to 2,249 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e2 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e4 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eDisclaimer: \u003c\/em\u003e\u003c\/strong\u003e\u003cem\u003eThis dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eApproved Starting Dose: \u003c\/strong\u003eIs labeled for an initial dosage of 2 mcg per kg body weight once daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustment Range: \u003c\/strong\u003eDosage is approved for adjustment based on endocrine testing response, not exceeding 4 mcg per kg daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTablet Scoring: \u003c\/strong\u003eTablets are scored and labeled to allow dosing to the nearest one-half tablet increment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Status: \u003c\/strong\u003eFederal law restricts this product to use by or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Use: \u003c\/strong\u003eThe manufacturer has not evaluated or confirmed the safety of this product for use in breeding horses, pregnant mares, or lactating animals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions: \u003c\/strong\u003eUsing this medication alongside dopamine antagonists may lessen its effectiveness because the drugs work against each other pharmacologically.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtein Binding: \u003c\/strong\u003ePergolide binds strongly to proteins, so extra care is needed when it is given with other medications that also have high protein-binding properties.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Exposure: \u003c\/strong\u003eTo reduce the risk of accidental human exposure during handling, the tablets should not be crushed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDecreased Appetite: \u003c\/strong\u003eInappetence was commonly reported, particularly during the first month of treatment in clinical studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Signs: \u003c\/strong\u003eColic and loose stool have been reported during both pre-approval and post-approval monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavior Changes: \u003c\/strong\u003eBehavioral effects such as agitation, aggression, or increased activity have been observed in some horses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaminitis Risk: \u003c\/strong\u003eBoth new and recurring cases of laminitis were reported during clinical safety evaluations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage Temperature Guideline: \u003c\/strong\u003eThe product should be kept at temperatures no higher than 25°C or 77°F to maintain quality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Storage: \u003c\/strong\u003eMust be stored securely to prevent accidental ingestion by dogs, cats, or other animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is PRASCEND used for in horses?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PRASCEND is approved by the FDA to help manage clinical signs linked to Pituitary Pars Intermedia Dysfunction in horses. When used with veterinary guidance, it helps address hormone-driven concerns such as long or abnormal hair growth, uneven fat buildup, muscle loss, and other signs commonly seen with PPID.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How does PRASCEND work in horses with PPID?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PRASCEND contains \u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Pergolide-Mesylate\" target=\"_blank\" rel=\"noopener\" title=\"Pergolide mesylate | c20h30n2o3s2 | cid 47812 - pubchem\" aria-label=\"Visit a webpage about Pergolide mesylate | c20h30n2o3s2 | cid 47812 - pubchem\"\u003epergolide mesylate\u003c\/a\u003e, a dopamine receptor agonist. In horses with PPID, it helps stimulate dopamine receptors, which have been shown to reduce elevated ACTH and other related hormone levels involved in the disease process.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: Is PRASCEND a prescription medication?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, PRASCEND is a prescription-only veterinary medication. Federal law restricts its use to horses treated by or on the order of a licensed veterinarian, ensuring appropriate diagnosis, dosing oversight, and ongoing monitoring during treatment.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: What are the common side effects reported with PRASCEND?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The most commonly reported side effects include decreased appetite, lethargy, diarrhea, colic, behavioral changes, and laminitis. Many cases were transient and occurred early in treatment, though post-approval reports indicate effects may also occur after dose adjustments.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: How should PRASCEND be stored?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns: \u003c\/strong\u003ePRASCEND tablets should be stored at temperatures of 25°C or 77°F or lower. Keep the product in a safe place to avoid accidental access by dogs, cats, or other animals. \u003c\/p\u003e","brand":"Boehringer Ingelheim","offers":[{"title":"160 Tablets","offer_id":41235863011489,"sku":"131356","price":432.99,"currency_code":"USD","in_stock":true},{"title":"60 Tablets","offer_id":41235863044257,"sku":"139668","price":190.0,"currency_code":"USD","in_stock":true},{"title":"1 Tablet","offer_id":41235863077025,"sku":"139668-1","price":2.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/prascend-pergolide-for-horses-1-mg-tablets-pet-medicine-714.webp?v=1778035089","url":"https:\/\/hordypaw.shop\/products\/prascend-tablets-for-horses-1-mg","provider":"HardyPaw","version":"1.0","type":"link"}