{"product_id":"ondansetron-injection-2mg-ml-20-ml","title":"Ondansetron Injection 2mg\/mL (20 mL)","description":"\u003cp\u003e\u003cimg loading=\"lazy\" data-files=\"rx-map.jpg\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" width=\"700\" alt=\"RX MAP\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\"\u003e\u003c\/p\u003e\n\u003ch2\u003eInjectable Antiemetic to Prevent and Treat Severe Vomiting in Pets\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eOndansetron HCl Injection 2mg\/mL is a prescription antiemetic used by veterinarians for dogs and cats experiencing severe vomiting and nausea. It works by latching onto 5HT3 serotonin receptors on vagal nerve terminals and enteric neurons in the gastrointestinal tract, as well as in the brain's chemoreceptor trigger zone, shutting down the vomiting reflex at multiple points simultaneously. It is particularly effective for chemotherapy-induced vomiting, post-operative nausea, and serious gastrointestinal illness, and is used off-label in veterinary medicine.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemotherapy Vomiting Control:\u003c\/strong\u003e Works well at preventing and bringing down vomiting episodes tied to cancer \u003ca href=\"\/collections\/dog-cancer-tumor-medications\" target=\"_blank\" rel=\"noopener\" title=\"Dog cancer \u0026amp; tumor medications: support \u0026amp; recovery | hardypaw\" aria-label=\"Dog cancer \u0026amp; tumor medications: support \u0026amp; recovery | hardypaw\"\u003echemotherapy treatment in dogs\u003c\/a\u003e and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDual-Site Mechanism:\u003c\/strong\u003e Takes on serotonin receptors in both the gastrointestinal tract and the brain's chemoreceptor trigger zone for thorough vomiting control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-Operative Nausea Relief:\u003c\/strong\u003e Given after surgery to keep nausea and vomiting under control during recovery in dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eParvoviral Enteritis Support:\u003c\/strong\u003e Performs as well as metoclopramide and maropitant in bringing vomiting frequency down in dogs with parvoviral enteritis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFast-Acting Injectable Delivery:\u003c\/strong\u003e The injectable route gets the antiemetic effect going reliably within one to two hours of administration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eOndansetron Hydrochloride 2mg\/mL\u003c\/p\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eSodium citrate, citric acid monohydrate, water for injection\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eOndansetron HCl Injection 2mg\/mL is a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eKnown Allergy Contraindication:\u003c\/strong\u003e Pets with a known sensitivity or allergy to ondansetron or related 5HT3 receptor antagonist medications should not receive this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Liver Disease:\u003c\/strong\u003e Reduced liver function slows how ondansetron is broken down, which can allow the drug to build up and raise the risk of side effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Cardiac Conditions:\u003c\/strong\u003e Pets with known cardiac arrhythmias or those on medications that affect heart rhythm need careful management before starting this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Pregnancy:\u003c\/strong\u003e How this medication affects pregnant or nursing animals is not fully established, so a veterinarian should review the situation before use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInspect Before Use:\u003c\/strong\u003e Check the vial before every use and set it aside if the solution looks hazy, off in color, or has anything visible floating in it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interaction Risk:\u003c\/strong\u003e Share a full list of your pet's current medications, particularly any serotonergic drugs, with your veterinarian before starting ondansetron.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSedation and Lethargy:\u003c\/strong\u003e Some drowsiness and lower energy can show up in dogs and cats following ondansetron administration and are worth monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eConstipation or Diarrhea:\u003c\/strong\u003e Shifts in bowel habits, whether toward constipation or loose stools, can come up and should be kept an eye on throughout treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtrapyramidal Signs:\u003c\/strong\u003e Head shaking and involuntary movements, known as extrapyramidal signs, are an uncommon but noted reaction in some pets on this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac Arrhythmias:\u003c\/strong\u003e Arrhythmias and low blood pressure are rare but serious reactions that need immediate veterinary attention if they show up during treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eControlled Room Temperature:\u003c\/strong\u003e Store vials somewhere cool and dry, maintaining a temperature of 68°F to 77°F and keeping them away from heat and temperature extremes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Light:\u003c\/strong\u003e Keeping the vials away from direct sunlight helps the solution hold its potency and stay stable throughout its shelf life.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOut of Reach:\u003c\/strong\u003e Keep this medication somewhere children and untreated animals in the home cannot get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNOTE:\u003c\/strong\u003e\u003c\/span\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What conditions does ondansetron injection treat in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Ondansetron injection covers severe vomiting from chemotherapy, post-operative recovery, parvoviral enteritis, and serious gastrointestinal illness in dogs and cats. It may also be used in some pets for pruritus and sleep apnea. A veterinarian will assess whether ondansetron is the right antiemetic choice for the specific condition being treated.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does ondansetron work differently from other antiemetics like metoclopramide?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Where metoclopramide primarily works as a dopamine antagonist, ondansetron goes after 5HT3 serotonin receptors in the gut and the brain's chemoreceptor trigger zone through a completely different pathway. That distinction makes ondansetron particularly strong for chemotherapy-induced vomiting and equally effective as metoclopramide and maropitant for parvoviral enteritis in dogs.\u003c\/p\u003e\n\u003ch3\u003eQ3: Is ondansetron injection FDA-approved for use in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Ondansetron only holds FDA approval for human use. Veterinarians are legally able to prescribe it for dogs and cats under extra-label use regulations, which cover situations where no approved veterinary alternative exists for a particular condition. A veterinarian will determine whether it is the right fit for a specific pet's needs.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can ondansetron injection be given to cats undergoing chemotherapy?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Research has shown that giving ondansetron intramuscularly before procedures meaningfully reduced nausea and vomiting in cats, making it a well-supported option for managing chemotherapy-associated vomiting. A veterinarian will work out the right dose and timing as part of the cat's overall cancer treatment plan.\u003c\/p\u003e\n\u003ch3\u003eQ5: What signs indicate a serious reaction to ondansetron in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Serious reactions are uncommon but can include cardiac arrhythmias, a significant drop in blood pressure, heavy sedation, involuntary head shaking or muscle movements, or allergic signs like facial swelling or collapse. Any of these showing up after administration should prompt an immediate call to a veterinarian or emergency clinic.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/fda\/fdaDrugXsl.cfm?setid=a62e2a6a-6235-7580-e053-2a95a90aa2b0\" title=\"Ondansetron injection, usp 40 mg\/20 ml (2 mg\/ml) 20 ml vial\" aria-label=\"Visit a webpage about Ondansetron injection, usp 40 mg\/20 ml (2 mg\/ml) 20 ml vial\"\u003ehttps:\/\/dailymed.nlm.nih.gov\/dailymed\/fda\/fdaDrugXsl.cfm?setid=a62e2a6a-6235-7580-e053-2a95a90aa2b0\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.medicines.org.uk\/emc\/product\/11553\/smpc\" title=\"Ondansetron 2mg\/ml solution for injection - summary of product characteristics (smpc) - (emc) | 11553\" aria-label=\"Visit a webpage about Ondansetron 2mg\/ml solution for injection - summary of product characteristics (smpc) - (emc) | 11553\"\u003ehttps:\/\/www.medicines.org.uk\/emc\/product\/11553\/smpc\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Varies (Generic)","offers":[{"title":"Default Title","offer_id":43325005299873,"sku":"484360","price":11.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/ondansetron-injection-2mg-ml-20-ml-pet-medicine-722.png?v=1778527915","url":"https:\/\/hordypaw.shop\/products\/ondansetron-injection-2mg-ml-20-ml","provider":"HardyPaw","version":"1.0","type":"link"}