{"product_id":"lisinopril-20mg-w-hydrochlorothiazide-12-5mg-tablets","title":"Lisinopril 20mg and Hydrochlorothiazide 12.5mg Tablets","description":"\u003cp\u003e\u003cimg width=\"700\" alt=\"RX MAP\" class=\"img-responsive\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eDual-Action Blood Pressure Support Tablet for Dogs and Cats\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eLisinopril 20 mg and Hydrochlorothiazide 12.5 mg Tablets pair two off-label generics in one prescription tablet for \u003ca href=\"\/collections\/heart-blood-pressure\" target=\"_blank\" rel=\"noopener\" title=\"Heart \u0026amp; blood pressure medications for dogs \u0026amp; cats – enalapril, cardalis | hardypaw\" aria-label=\"Heart \u0026amp; blood pressure medications for dogs \u0026amp; cats – enalapril, cardalis | hardypaw\"\u003emanaging high blood pressure in dogs and cats\u003c\/a\u003e. Lisinopril opens and relaxes blood vessels while Hydrochlorothiazide helps the kidneys clear excess fluid and salt, together delivering a dual approach to cardiovascular health under veterinary supervision.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eDual Blood Pressure Control:\u003c\/strong\u003e Goes after both vessel constriction and fluid retention together, providing thorough blood pressure management for dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Vessel Relaxation:\u003c\/strong\u003e Blocks the vessel-constricting enzyme to keep blood vessels open, allowing freer blood flow throughout the cardiovascular system in pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluid and Salt Removal:\u003c\/strong\u003e Hydrochlorothiazide flushes excess water and sodium out through the kidneys, cutting the fluid load on the cardiovascular system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Failure Support:\u003c\/strong\u003e Lisinopril paired with diuretics has demonstrated improved quality of life in dogs managing congestive heart failure over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKidney Health Support:\u003c\/strong\u003e Reduces pressure within the kidneys in some pets, potentially supporting better renal perfusion in certain kidney disease types.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFDA-Approved Generic Components:\u003c\/strong\u003e Both lisinopril and hydrochlorothiazide are individually FDA-approved generics widely used off-label in veterinary practice for pets.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eLisinopril, Hydrochlorothiazide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cp\u003eLisinopril 20 mg and Hydrochlorothiazide 12.5 mg Tablets are a prescription-only medication. A valid prescription from a licensed veterinarian is required before this product can be purchased or dispensed. Always follow your veterinarian's specific guidance on giving this medication to your pet and make sure fresh water is available at all times throughout treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eIf getting your pet to take a tablet is a challenge, a pill pocket or pill wrap can be a real game-changer. Simply wrap the tablet in a soft treat and offer it as you normally would — most pets accept it without any fuss, making the whole process quick and stress-free for both of you. \u003ca href=\"\/collections\/pill-pockets-for-dogs\" title=\"Shop pill pockets for dogs\" aria-label=\"Shop pill pockets for dogs\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/collections\/pill-pockets-for-cats\" title=\"Shop pill pockets for cats\" aria-label=\"Shop pill pockets for cats\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eACE Inhibitor Allergy:\u003c\/strong\u003e Avoid in pets with a known reaction to lisinopril, benazepril, enalapril, or any other ACE inhibitor medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKidney Disease Caution:\u003c\/strong\u003e Both ingredients affect renal function; pets with existing kidney disease need careful veterinary assessment before this product is started.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant or Breeding Pets:\u003c\/strong\u003e Fetal defect risk makes lisinopril off-limits in pregnant animals; hydrochlorothiazide also carries a relative contraindication during pregnancy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e NSAIDs, insulin, digoxin, potassium supplements, and other blood pressure drugs interact with this combination; keep your vet fully informed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSulfa Allergy Warning:\u003c\/strong\u003e A sulfonamide-related drug; avoid in pets with sulfa allergies unless the benefit genuinely and clearly outweighs the potential risks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegular Monitoring Required:\u003c\/strong\u003e Blood pressure checks and bloodwork covering electrolytes and kidney values are needed periodically to confirm safe and effective treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting and Diarrhoea:\u003c\/strong\u003e Vomiting and loose stools are among the most frequently reported reactions from lisinopril use in dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Urination:\u003c\/strong\u003e Hydrochlorothiazide increases urination, which may make some pets restless; ensure frequent outdoor access or litter tray availability throughout treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Blood Pressure:\u003c\/strong\u003e Both drugs together can bring on hypotension; watch for weakness or collapse, especially in pets that become dehydrated.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Potassium and chloride may drop; muscle weakness, fatigue, or abnormal heart rhythm signal an electrolyte problem in treated pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExcessive Thirst:\u003c\/strong\u003e A sudden jump in water intake may signal an electrolyte or kidney imbalance; contact your vet promptly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reaction Signs:\u003c\/strong\u003e Rash, fever, breathing trouble, or facial swelling call for stopping this product at once and contacting your vet.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at room temperature away from heat and direct light to preserve the stability of both active ingredients.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect from Moisture:\u003c\/strong\u003e A tightly sealed container in a dry location stops humidity from degrading these tablets throughout their shelf life.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStore Safely Out of Reach:\u003c\/strong\u003e Keep away from other animals and children; accidental ingestion of either component can bring on serious health consequences.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNOTE:\u003c\/strong\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy\" aria-label=\"Shipping policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What conditions are lisinopril and hydrochlorothiazide used for together in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Used off-label in dogs and cats for high blood pressure and heart failure, lisinopril opens blood vessels by blocking a constricting enzyme while hydrochlorothiazide reduces fluid load through the kidneys. Together they deliver more comprehensive blood pressure control for affected pets.\u003c\/p\u003e\n\u003ch3\u003eQ2: Can lisinopril and hydrochlorothiazide cause kidney problems in dogs or cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both medications can affect kidney function, particularly in pets with existing renal disease. Kidney health is assessed before starting, and periodic blood and urine testing throughout treatment keeps kidney values and overall renal safety under close watch.\u003c\/p\u003e\n\u003ch3\u003eQ3: What should I do if my pet drinks a lot more water while on this medication?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Drinking more than usual can signal an electrolyte imbalance or early kidney stress from hydrochlorothiazide. Contact your vet promptly if water intake increases noticeably, as a dose adjustment or additional monitoring may be needed to keep your pet safe.\u003c\/p\u003e\n\u003ch3\u003eQ4: Are there any medications my pet should not take alongside this combination?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. NSAIDs, insulin, potassium supplements, digoxin, other diuretics, and additional blood pressure drugs all have the potential to interact with this combination. Give your vet a full and current list of every product your pet is on before starting treatment.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is this combination tablet safe for cats as well as dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, both lisinopril and hydrochlorothiazide are used off-label in dogs and cats under vet supervision. Neither carries veterinary FDA approval, so a valid prescription and close monitoring throughout treatment are both essential before giving this combination to any pet.\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 tablet","offer_id":44430204141729,"sku":"153313-1","price":0.08,"currency_code":"USD","in_stock":true},{"title":"30 tablets","offer_id":44430204174497,"sku":"153313-30","price":2.1,"currency_code":"USD","in_stock":true},{"title":"60 tablets","offer_id":44430204207265,"sku":"153313-60","price":3.6,"currency_code":"USD","in_stock":true},{"title":"100 tablets","offer_id":44430204240033,"sku":"153313","price":5.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/lisinopril-20mg-and-hydrochlorothiazide-12-5mg-tablets-pet-medicine-644.png?v=1778755823","url":"https:\/\/hordypaw.shop\/products\/lisinopril-20mg-w-hydrochlorothiazide-12-5mg-tablets","provider":"HardyPaw","version":"1.0","type":"link"}