{"product_id":"lisinopril-10mg-and-hydrochlorothiazide-12-5mg-tablets","title":"Lisinopril 10mg and Hydrochlorothiazide 12.5mg Tablets","description":"\u003cp\u003e\u003cimg src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003eLisinopril and Hydrochlorothiazide Tablets for Pet Hypertension\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eLisinopril 10 mg and Hydrochlorothiazide 12.5 mg Tablets pair a prescription-only ACE inhibitor with a thiazide diuretic in one tablet used off-label in \u003ca href=\"\/collections\/heart-blood-pressure\" title=\"Heart \u0026amp; blood pressure medications for dogs \u0026amp; cats – enalapril, cardalis | hardypaw\" aria-label=\"Heart \u0026amp; blood pressure medications for dogs \u0026amp; cats – enalapril, cardalis | hardypaw\"\u003edogs and cats for systemic hypertension\u003c\/a\u003e. Lisinopril opens blood vessels by blocking angiotensin II, while hydrochlorothiazide clears excess sodium and water through the kidneys, tackling two key drivers of high blood pressure at once.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eDual Mechanism Action:\u003c\/strong\u003e An ACE inhibitor and a diuretic working together in one tablet tackle blood vessel tension and excess fluid volume at the same time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eACE Inhibitor Benefits:\u003c\/strong\u003e By shutting down angiotensin II, lisinopril lets blood vessels open up and takes pressure off the cardiovascular system in treated pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiuretic Fluid Reduction:\u003c\/strong\u003e Hydrochlorothiazide gets the kidneys moving excess sodium and water out of the body, helping pull fluid volume and blood pressure down.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypertension Management:\u003c\/strong\u003e Addresses vasoconstriction and fluid retention together, hitting both key drivers of persistent high blood pressure in dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart and Kidney Support:\u003c\/strong\u003e Lisinopril supports dogs with heart failure and addresses certain \u003ca href=\"\/collections\/dog-kidney-urinary-medications\" title=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\" aria-label=\"Dog kidney \u0026amp; urinary tract medications: prevent stones \u0026amp; infections | hardypaw\"\u003ekidney disease\u003c\/a\u003e types when paired with other cardiac medications.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003ctable style=\"width: 58.5954%; height: 45px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 57.7816%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 41.9412%; height: 19.6023px;\"\u003e\u003cstrong\u003eStrength per Tablet\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 57.7816%; height: 19.6023px;\"\u003eLisinopril (Active)\u003c\/td\u003e\n\u003ctd style=\"width: 41.9412%; height: 19.6023px;\"\u003e10 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 57.7816%; height: 19.6023px;\"\u003eHydrochlorothiazide (Active)\u003c\/td\u003e\n\u003ctd style=\"width: 41.9412%; height: 19.6023px;\"\u003e12.5 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cp\u003eLisinopril 10 mg and Hydrochlorothiazide 12.5 mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's instructions carefully for the dosage and administration of this medication.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003ePlacing a tablet inside a soft Pill Pocket or wrapping it in a small piece of your pet's favorite treat is a simple and caring way to make each dose easier for both of you. A pill pocket treat takes the stress out of medicating your pet and helps ensure no dose is missed. \u003ca href=\"\/collections\/pill-pockets-for-dogs\" title=\"Shop pill pockets for dogs\" aria-label=\"Shop pill pockets for dogs\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/collections\/pill-pockets-for-cats\" title=\"Shop pill pockets for cats\" aria-label=\"Shop pill pockets for cats\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eACE Inhibitor Allergy:\u003c\/strong\u003e Avoid in pets allergic to lisinopril, benazepril, enalapril, or any other medication within the ACE inhibitor class.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalance Risk:\u003c\/strong\u003e Persistent vomiting or diarrhea causing electrolyte disruption is a reason to avoid this product in affected pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSevere Kidney Impairment:\u003c\/strong\u003e Both ingredients can add renal strain; use with extra care in pets already dealing with significant kidney disease.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy Caution:\u003c\/strong\u003e Both ingredients may harm developing fetuses or nursing young; never give to pregnant or lactating animals under any circumstances.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLupus and Autoimmune History:\u003c\/strong\u003e Tell your vet about any history of lupus, blood issues, or autoimmune conditions before this product is started.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotassium Level Risk:\u003c\/strong\u003e Hydrochlorothiazide depletes potassium; electrolyte levels must be monitored carefully when this product is used with other potassium-affecting drugs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Cholestyramine, colestipol, NSAIDs, potassium supplements, and ARBs such as losartan all interact with this combination in treated pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBaseline Testing Required:\u003c\/strong\u003e Electrolytes, kidney values, and blood pressure all need a clean bill of health before treatment starts and should be revisited at regular intervals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Stop Abruptly:\u003c\/strong\u003e Speak to your vet before making any changes to this treatment; stopping suddenly can cause blood pressure to spike to a harmful level.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Only:\u003c\/strong\u003e Neither ingredient has received veterinary FDA clearance; both require a licensed veterinarian to place the order before this product can go out.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Blood Pressure:\u003c\/strong\u003e Lethargy, weakness, and difficulty standing may signal low blood pressure developing in dogs or cats on this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKidney Dysfunction:\u003c\/strong\u003e Increased thirst or urination changes may signal kidney stress from lisinopril; monitor these signs closely throughout treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Abnormalities:\u003c\/strong\u003e Hydrochlorothiazide can cause low potassium, sodium, or magnesium, leading to muscle weakness or irregular heartbeat in treated pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting and Diarrhea:\u003c\/strong\u003e Gastrointestinal reactions including vomiting and loose stools are among the more frequently reported side effects in treated pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduced Appetite:\u003c\/strong\u003e Appetite loss can develop with lisinopril use; track food intake closely and flag any changes to your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Hives, facial swelling, or breathing difficulty require immediate stopping of this product and urgent emergency veterinary attention.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store in a sealed container at room temperature, keeping the tablets away from moisture, heat, and direct light.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Container Sealed:\u003c\/strong\u003e A firmly closed lid between each use stops moisture and air from degrading these tablets over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store in a secure place that children and other household animals cannot get into to prevent accidental ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNOTE:\u003c\/strong\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is the Lisinopril and Hydrochlorothiazide combination used for in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Used off-label in dogs and cats for systemic hypertension, lisinopril opens blood vessels by blocking angiotensin II while hydrochlorothiazide reduces fluid volume through the kidneys. Together they address both vasoconstriction and fluid retention in one daily tablet.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why is a combination tablet used instead of separate medications?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e A single tablet covering two mechanisms makes sense when one medication alone is not getting blood pressure under control. It also cuts down on the number of individual pills an owner has to manage and administer each day.\u003c\/p\u003e\n\u003ch3\u003eQ3: What electrolyte changes should I watch for in my pet on this combination?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Hydrochlorothiazide can lower potassium, sodium, and magnesium levels, showing up as muscle weakness, lethargy, or an irregular heartbeat in affected pets. Regular blood tests throughout treatment are needed to keep electrolyte levels and kidney values within a safe range.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can this medication affect my pet's kidneys?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. Lisinopril has been linked to kidney dysfunction in some pets, and hydrochlorothiazide affects fluid and electrolyte balance. Heavier thirst or urination changes may signal kidney stress. Regular blood work and urinalysis throughout treatment help keep renal health in check.\u003c\/p\u003e\n\u003ch3\u003eQ5: Do I need a prescription for Lisinopril and Hydrochlorothiazide Tablets for my pet?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, this is a prescription-only combination. Neither ingredient carries veterinary FDA approval, and both can only be dispensed on a licensed veterinarian's order. Regular monitoring appointments throughout treatment are an essential part of keeping your pet safe on this product.\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 tablet","offer_id":44430206107809,"sku":"153150-1","price":0.09,"currency_code":"USD","in_stock":true},{"title":"30 tablets","offer_id":44430206140577,"sku":"153150-30","price":2.4,"currency_code":"USD","in_stock":true},{"title":"60 tablets","offer_id":44430206173345,"sku":"153150-60","price":4.2,"currency_code":"USD","in_stock":true},{"title":"100 tablets","offer_id":44430206206113,"sku":"153150","price":6.15,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/lisinopril-10mg-and-hydrochlorothiazide-12-5mg-tablets-pet-medicine-891.png?v=1778557530","url":"https:\/\/hordypaw.shop\/products\/lisinopril-10mg-and-hydrochlorothiazide-12-5mg-tablets","provider":"HardyPaw","version":"1.0","type":"link"}