{"product_id":"factrel-injection-gonadorelin-injection-for-cattle","title":"Factrel Injection (gonadorelin injection) for Cattle","description":"\u003ch2\u003eGnRH Injection for Ovarian Cysts and FTAI in Cattle\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eFactrel (Gonadorelin Hydrochloride) Injection 50 mcg\/mL is an FDA-approved prescription GnRH solution for intramuscular use in cattle only. Each mL contains 50 mcg synthetic gonadorelin identical in amino acid sequence to natural bovine GnRH, in sodium chloride with benzyl alcohol as preservative. It treats ovarian follicular cysts and synchronizes estrous cycles for FTAI when used with LUTALYSE, with no withdrawal period.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTreats Ovarian Follicular Cysts:\u003c\/strong\u003e Cuts down days to first estrus in lactating dairy cows, beef cows, and replacement heifers dealing with ovarian follicular cysts.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eInduces Endogenous LH Release:\u003c\/strong\u003e Stimulates the anterior pituitary to release endogenous LH and FSH, triggering ovulation or luteinization of cystic ovarian follicles.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFTAI Protocol Compatible:\u003c\/strong\u003e Used with LUTALYSE in validated estrous synchronization protocols to allow fixed-time artificial insemination in dairy cows.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSignificantly Improves FTAI Rates:\u003c\/strong\u003e In a 1,142-cow study, Factrel with LUTALYSE reached up to 32.2% pregnancy rates versus 17.1% for LUTALYSE alone.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNo Withdrawal Period:\u003c\/strong\u003e No milk discard or preslaughter waiting period is needed for cattle treated with Factrel as directed.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBioidentical to Natural GnRH:\u003c\/strong\u003e Gonadorelin in Factrel shares the exact amino acid sequence as naturally occurring bovine hypothalamic GnRH in cattle.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eWide Safety Margin:\u003c\/strong\u003e Given at up to 12.5 times the label dose for 3 days with no adverse physiological effects seen in safety studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eVariants\u003c\/h3\u003e\n\u003cp\u003eFactrel Injection 20 mL Multi-Dose Vial\u003c\/p\u003e\n\u003cp\u003eFactrel Injection 50 mL Multi-Dose Vial\u003c\/p\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eGonadorelin (as Gonadorelin Hydrochloride): 50 mcg per mL\u003c\/p\u003e\n\u003ch4\u003eInactive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSodium chloride 0.6%, benzyl alcohol 2% (as preservative), water for injection\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage and Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Federal law restricts Factrel Injection to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCystic Ovary Dose:\u003c\/strong\u003e Give 2 mL (100 mcg) as a single IM injection per cow to treat ovarian follicular cysts.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFTAI Protocol Dose:\u003c\/strong\u003e Give 2 to 4 mL (100 to 200 mcg) per cow as both the first and second IM injection in the LUTALYSE-based FTAI protocol.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFTAI Day 0:\u003c\/strong\u003e Give the first Factrel dose of 2 to 4 mL by IM injection on Day 0 to kick off the synchronization protocol.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFTAI Day 6-8:\u003c\/strong\u003e Give 25 mg LUTALYSE (5 mL dinoprost tromethamine) by IM injection 6 to 8 days after the first Factrel dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFTAI Day 8-10:\u003c\/strong\u003e Give the second Factrel dose of 2 to 4 mL between 30 and 72 hours after LUTALYSE is given.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFTAI Timing:\u003c\/strong\u003e Perform FTAI within 0 to 24 hours after the second Factrel dose or on detected estrus.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eVial Use Window:\u003c\/strong\u003e Once the vial is first opened, use the contents within one month and discard anything left after that.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCattle Only:\u003c\/strong\u003e Factrel Injection is approved for intramuscular use in cattle only; do not administer to other animal species.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCyst Treatment Outcomes:\u003c\/strong\u003e Factrel cut days to first estrus in cyst-treated cows but did not significantly improve conception rates when used on its own.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eOnly Use With LUTALYSE:\u003c\/strong\u003e The FTAI indication requires LUTALYSE specifically; do not swap in other prostaglandins without veterinary guidance.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHuman Safety:\u003c\/strong\u003e For animal use only; keep well away from children and never use on or near humans at any time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNo Adverse Events:\u003c\/strong\u003e No injection site irritation or physiological effects were seen even at 12.5 times the label dose in safety studies.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIncidental Health Events:\u003c\/strong\u003e In the 1,142-cow field study, health events like mastitis, lameness, and pneumonia were noted but considered unrelated to Factrel.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRefrigerator Storage Required:\u003c\/strong\u003e Store at 2 to 8°C (36 to 46°F); brief exposure up to 25°C (77°F) is tolerated but should be kept to a minimum.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eUse Within 1 Month:\u003c\/strong\u003e After the vial is first opened, throw out any unused solution one month later to keep the product sterile.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store in a locked, secure spot away from children and all animals at all times.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What is Factrel gonadorelin injection used for in cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Factrel is FDA-approved for two uses in cattle: treating ovarian follicular cysts in lactating dairy cows, beef cows, and replacement heifers to cut down days to first estrus, and syncing estrous cycles for fixed-time artificial insemination in lactating dairy cows when paired with LUTALYSE Injection.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: What is the correct dose of Factrel GnRH injection for cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e For ovarian cysts, give 2 mL (100 mcg) as a single IM injection per cow. For FTAI with LUTALYSE, give 2 to 4 mL at Day 0 and again 30 to 72 hours after the LUTALYSE injection, then perform FTAI within 24 hours of the second dose.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: Is there a milk discard or withdrawal period for Factrel gonadorelin in cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No milk discard or preslaughter withdrawal is needed when Factrel is used according to the label. It works for both lactating dairy cows and beef cattle without any production downtime, which makes it a practical fit for day-to-day herd management programs.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: What is the difference between the Factrel 20 mL and 50 mL vials?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both vials contain the identical 50 mcg\/mL gonadorelin hydrochloride concentration and formulation. The 20 mL vial (1,000 mcg total) suits smaller herds or shorter programs, while the 50 mL vial (2,500 mcg total) is economical for large-scale FTAI synchronization programs requiring higher volume.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: How does Factrel GnRH injection treat ovarian cysts in dairy and beef cows?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e When ovarian cysts develop from a failure of normal ovulation, Factrel pushes the anterior pituitary to release LH, which triggers the cystic follicle to ovulate or luteinize. This gets the cow back cycling sooner, though using Factrel alone did not show a significant boost in conception rates compared to untreated cows.\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"20-ml (50mcg\/ml)","offer_id":44865970274465,"sku":"10011520","price":30.99,"currency_code":"USD","in_stock":true},{"title":"50-ml (50mcg\/ml)","offer_id":44865970307233,"sku":"10011531","price":70.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/factrel-injection-gonadorelin-injection-for-cattle-pet-medicine-548.jpg?v=1779792129","url":"https:\/\/hordypaw.shop\/products\/factrel-injection-gonadorelin-injection-for-cattle","provider":"HardyPaw","version":"1.0","type":"link"}