{"product_id":"diphenhydramine-hci-capsules-25mg","title":"Diphenhydramine HCI Capsules (Manufacturer may vary","description":"\u003ch2\u003eDiphenhydramine HCl Capsules for Allergies and Anxiety in Pets\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eDiphenhydramine HCl 25 mg Capsules are a prescription-dispensed, first-generation antihistamine for dogs and cats used to \u003ca href=\"\/collections\/skin-irritation\" title=\"Prescription skin treatments for pets – animax, triamcinolone | hardypaw\" aria-label=\"Prescription skin treatments for pets – animax, triamcinolone | hardypaw\"\u003eease allergy symptoms\u003c\/a\u003e, insect bite reactions, motion sickness, and travel anxiety. It works by blocking H1 histamine receptors to bring down itching, swelling, and sneezing in affected pets. The 25 mg strength is a lighter option well suited to smaller animals or those starting on a lower dose under veterinary care.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRelieves Allergy Symptoms:\u003c\/strong\u003e Blocks H1 histamine receptors to ease itching, sneezing, watery eyes, and hives triggered by seasonal or environmental allergens in pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsect Bite Relief:\u003c\/strong\u003e Brings down swelling, itching, and soreness caused by insect bites and stings in dogs and cats under veterinary guidance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMotion Sickness Control:\u003c\/strong\u003e The antiemetic and calming properties of this medication help reduce nausea and vomiting linked to motion sickness in treated pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMild Anxiety Support:\u003c\/strong\u003e Offers a mild settling effect during unsettling events such as vet visits or car travel when recommended and prescribed by a veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLower Strength Option:\u003c\/strong\u003e The 25 mg capsule is the right fit for small dogs, cats, or pets where a lighter prescribed dose has been recommended by a vet.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredient\u003c\/h4\u003e\n\u003ctable height=\"5\" style=\"width: 50.5809%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 64.2618%;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 35.281%;\"\u003e\u003cstrong\u003eStrength per Capsule\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 64.2618%;\"\u003eDiphenhydramine Hydrochloride (Active)\u003c\/td\u003e\n\u003ctd style=\"width: 35.281%;\"\u003e25 mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDirections for Use\u003c\/h4\u003e\n\u003cp\u003eDiphenhydramine HCl 25 mg Capsules are dispensed as a prescription medication at HardyPaw. A valid veterinarian prescription is required to purchase this product. Please follow your veterinarian's instructions carefully for the dosage and administration of this medication.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Your veterinarian should be contacted before starting or modifying any medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking a capsule inside a soft Pill Pocket or wrapping it in a small piece of your pet's favourite treat is a simple and stress-free way to make sure each dose goes down without a struggle. \u003ca aria-label=\"Shop pill pockets for dogs\" title=\"Shop pill pockets for dogs\" href=\"\/collections\/pill-pockets-for-dogs\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca aria-label=\"Shop pill pockets for cats\" title=\"Shop pill pockets for cats\" href=\"\/collections\/pill-pockets-for-cats\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlaucoma Caution:\u003c\/strong\u003e Do not use in pets with glaucoma, as the anticholinergic effects of this medication may push intraocular pressure to a harmful level.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Obstruction Risk:\u003c\/strong\u003e Pets with prostatic hypertrophy or bladder neck obstruction should not receive this product, as urinary retention is a recognised anticholinergic effect.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRespiratory Disease:\u003c\/strong\u003e Take extra care in pets with breathing difficulties, as this medication may thicken secretions and make existing respiratory problems noticeably worse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnancy and Lactation:\u003c\/strong\u003e Keep away from pregnant or nursing animals, as antihistamines can interfere with fetal development and find their way into nursing milk.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergy Skin Testing:\u003c\/strong\u003e Stop giving this product at least two weeks ahead of any planned intradermal allergy testing, as it can throw off accurate test outcomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWorking Animal Caution:\u003c\/strong\u003e Use carefully in service, police, or working animals, since the sedation this product causes can get in the way of their duties and performance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Extra care is needed when combining with CNS depressants, barbiturates, tricyclic antidepressants, epinephrine, or heparin in any treated pet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSevere Allergic Reactions:\u003c\/strong\u003e This product is not the right response to serious anaphylaxis involving breathing trouble, facial swelling, or collapse; these need emergency veterinary care immediately.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Combination Products:\u003c\/strong\u003e Human diphenhydramine formulations that contain decongestants or pain relievers must never be given to pets as those additives are toxic.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e This product is dispensed as a prescription medication at HardyPaw; a valid veterinarian prescription must be in place before purchase.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrowsiness and Sedation:\u003c\/strong\u003e The most frequently noted reaction; sedation tends to be strongest with the opening dose and generally softens with continued treatment over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDry Mouth:\u003c\/strong\u003e Reduced saliva output is a known anticholinergic effect of this product, and heavier-than-normal drooling has been noted particularly in cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Retention:\u003c\/strong\u003e Some pets, especially those with existing urinary or prostate issues, may find passing urine more difficult while on this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVomiting and Diarrhea:\u003c\/strong\u003e Occasional stomach upset including loose stools and vomiting has been reported in a number of pets taking this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eParadoxical Excitement:\u003c\/strong\u003e Rather than settling down, some cats become unusually active or restless; keeping them in a calm, confined space until this passes is advisable.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOverdose Signs:\u003c\/strong\u003e Seizures, extreme drowsiness, coma, or slowed breathing may point to an overdose; get emergency veterinary help without any delay.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Temperatures between 59°F and 86°F in a dry, low-light area of the home are what this product needs to stay in good condition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Bathroom Storage:\u003c\/strong\u003e The humidity and temperature shifts in bathrooms can wear down capsule quality over time; a cool, stable indoor spot works better.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store in a secure location well away from children and other household animals to remove any chance of accidental ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eNOTE:\u003c\/strong\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca aria-label=\"Shipping policy | hardypaw\" title=\"Shipping policy | hardypaw\" href=\"\/pages\/shipping-policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca aria-label=\"Refund policy\" title=\"Refund policy\" href=\"\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is Diphenhydramine HCl 25 mg used for in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This antihistamine is used off-label in dogs and cats to ease allergy symptoms, insect bite reactions, and motion sickness. It blocks H1 histamine receptors to reduce itching, swelling, and sneezing. The 25 mg capsule suits smaller pets or those starting on a lower prescribed dose.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why is Diphenhydramine dispensed as a prescription at HardyPaw?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e HardyPaw is an NABP-authenticated Rx pharmacy where diphenhydramine is dispensed under veterinary prescription to keep its use safe and appropriate for every pet. A valid prescription confirms the right product and strength have been selected to match your pet's specific health needs.\u003c\/p\u003e\n\u003ch3\u003eQ3: What is the difference between the 25 mg and 50 mg Diphenhydramine capsules?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both hold the same active ingredient and work through the same mechanism. The 25 mg capsule is the lighter option, suited to smaller dogs, cats, and pets needing tighter dose control for allergy management. Your veterinarian will confirm the correct strength for your pet.\u003c\/p\u003e\n\u003ch3\u003eQ4: Is Diphenhydramine 25 mg safe for cats as well as dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, it is used in both species under veterinary guidance. Cats may occasionally respond with unusual excitement rather than sedation. Liquid versions can be tricky to give cats due to taste. Always follow your vet's instructions on strength and how often to give it.\u003c\/p\u003e\n\u003ch3\u003eQ5: What should I do if my pet shows signs of a Diphenhydramine overdose?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Extreme drowsiness, seizures, coma, or slowed breathing may all point to an overdose situation. If any of these warning signs show up, get your pet to a vet or emergency animal facility as fast as possible. Quick action is essential, as an overdose of this product can become life-threatening without prompt veterinary care.\u003c\/p\u003e\n\u003ch2\u003eClinical Research: \u003c\/h2\u003e\n\u003cp\u003e\u003ca aria-label=\"Visit a webpage about Https:\/\/www.tandfonline.com\/doi\/abs\/10.1081\/jlc-100101651\" title=\"Https:\/\/www.tandfonline.com\/doi\/abs\/10.1081\/jlc-100101651\" href=\"https:\/\/www.tandfonline.com\/doi\/abs\/10.1081\/JLC-100101651\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/www.tandfonline.com\/doi\/abs\/10.1081\/JLC-100101651\u003c\/a\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca aria-label=\"Visit a webpage about Https:\/\/japsonline.com\/admin\/php\/uploads\/110_pdf.pdf\" title=\"Https:\/\/japsonline.com\/admin\/php\/uploads\/110_pdf.pdf\" href=\"https:\/\/japsonline.com\/admin\/php\/uploads\/110_pdf.pdf\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/japsonline.com\/admin\/php\/uploads\/110_pdf.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"25-mg \/ 100 Capsules","offer_id":44494889648289,"sku":"201230","price":4.25,"currency_code":"USD","in_stock":true},{"title":"25-mg \/ 100 Tablets","offer_id":45815210148001,"sku":"3343258","price":4.25,"currency_code":"USD","in_stock":true},{"title":"50-mg \/ 100 Capsules","offer_id":45816168710305,"sku":"201210","price":5.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/diphenhydramine-hci-capsules-manufacturer-may-vary-25-mg-100-104.webp?v=1777918824","url":"https:\/\/hordypaw.shop\/products\/diphenhydramine-hci-capsules-25mg","provider":"HardyPaw","version":"1.0","type":"link"}