{"product_id":"cystorelin-sterile-solution-5ml","title":"Cystorelin Sterile Solution (Gonadorelin Diacetate Tetrahydrate)","description":"\u003ch2\u003eEffective Reproductive Support for Dairy and Beef Cattle\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eCYSTORELIN® (gonadorelin injection) is a prescription veterinary solution designed to \u003ca href=\"\/collections\/farm-animal-estrus-luteolytic-medications\" target=\"_blank\" rel=\"noopener\" title=\"Farm animal estrus medications: support for fertility \u0026amp; breeding | hardypaw\" aria-label=\"Farm animal estrus medications: support for fertility \u0026amp; breeding | hardypaw\"\u003esupport reproductive health in dairy and beef cattle\u003c\/a\u003e. It is used for the treatment of ovarian follicular cysts and is used with cloprostenol sodium to synchronize estrous cycles for fixed-time artificial insemination. By stimulating natural hormone release it promotes ovulation and improves breeding efficiency in managed herds.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormonal Activation: \u003c\/strong\u003eEncourages the release of key reproductive hormones like luteinizing hormone and follicle-stimulating hormone to support normal cycling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCyst Management: \u003c\/strong\u003eHelps in resolving ovarian follicular cysts by triggering ovulation and promoting proper luteinization in cattle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFertility Support: \u003c\/strong\u003eContributes to higher conception rates when incorporated into fixed-time artificial insemination protocols with cloprostenol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdministration Flexibility: \u003c\/strong\u003eSuitable for both intramuscular and intravenous use allowing veterinarians to tailor treatment approaches.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Withdrawal Requirement: \u003c\/strong\u003eDoes not require milk discard or withdrawal period when administered as per labeled veterinary guidelines.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eVariants\u003c\/h3\u003e\n\u003cp\u003e30 ml vial\u003c\/p\u003e\n\u003cp\u003e50 ml vial\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 47.2539%;\" height=\"109\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 80.7264%;\" width=\"451\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.0579%;\" width=\"106\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 80.7264%;\" width=\"451\"\u003e\n\u003cp\u003eGonadorelin diacetate tetrahydrate\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.0579%;\" width=\"106\"\u003e\n\u003cp\u003e50 mcg per ml\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 80.7264%;\" width=\"451\"\u003e\n\u003cp\u003eBenzyl Alcohol\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.0579%;\" width=\"106\"\u003e\n\u003cp\u003e9 mg per ml\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 80.7264%;\" width=\"451\"\u003e\n\u003cp\u003eSodium Chloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 19.0579%;\" width=\"106\"\u003e\n\u003cp\u003e7.47 mg per ml\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eRecommended-Dosage Chart\u003c\/h4\u003e\n\u003ctable height=\"219\" style=\"width: 47.4322%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.6822%;\" width=\"377\"\u003e\n\u003cp\u003e\u003cstrong\u003eCondition\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.1148%;\" width=\"99\"\u003e\n\u003cp\u003e\u003cstrong\u003eDosage\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.5675%;\" width=\"103\"\u003e\n\u003cp\u003e\u003cstrong\u003eRoute\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.6822%;\" width=\"377\"\u003e\n\u003cp\u003eCystic ovaries\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.1148%;\" width=\"99\"\u003e\n\u003cp\u003e2 ml (100 mcg gonadorelin) per cow\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.5675%;\" width=\"103\"\u003e\n\u003cp\u003eIntramuscular or Intravenous\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 49.6822%;\" width=\"377\"\u003e\n\u003cp\u003eEstrus synchronization\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.1148%;\" width=\"99\"\u003e\n\u003cp\u003e2 ml (100 mcg gonadorelin) per cow\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.5675%;\" width=\"103\"\u003e\n\u003cp\u003eIntramuscular (as part of protocol)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eInitial Injection\u003c\/strong\u003e: Administer the first 2 ml dose at the start of the synchronization protocol to initiate the hormonal response.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFollow-Up Protocol\u003c\/strong\u003e: Administer cloprostenol injection 6 to 8 days after the first dose to regulate estrous cycle timing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecond Dose Timing\u003c\/strong\u003e: Give the second CYSTORELIN dose 30 to 72 hours after cloprostenol administration for optimal synchronization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsemination Window\u003c\/strong\u003e: Perform fixed-time artificial insemination within 0 to 24 hours following the second gonadorelin injection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Supervision\u003c\/strong\u003e: This prescription product must be used under the direction of a licensed veterinarian as per federal regulations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer\u003c\/strong\u003e: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Safety\u003c\/strong\u003e: This is for animal use only and should be handled with care to avoid accidental exposure to humans.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away Children\u003c\/strong\u003e: Keep it securely stored and out of children’s reach to avoid unintended contact or ingestion.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Oversight\u003c\/strong\u003e: Always check with the veterinarian for proper diagnosis, dosing, and reproductive management results.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimal Health Concerns: \u003c\/strong\u003eShows no detectable increase in health issues when compared with animals receiving placebo treatments during research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProven Safety Profile: \u003c\/strong\u003eProduct has a high margin of safety across multiple species, with no meaningful impact on clinical markers or physiological well‑being.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInjection Site Tolerance: \u003c\/strong\u003eAnimals exhibited no notable irritation or negative reactions at the injection site when administered as per the veterinarian's guidance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTemperature Control\u003c\/strong\u003e: Store at or below 25°C (77°F) temperature to maintain product stability and effectiveness over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eShort Excursions\u003c\/strong\u003e: Short-term exposure up to 30°C (86°F) is permitted without compromising product integrity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-Opening Use\u003c\/strong\u003e: Use within six months after first vial puncture to ensure safety and therapeutic effectiveness.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/pages\/shipping-policy\" title=\"Shipping policy\" aria-label=\"Shipping policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e \u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is CYSTORELIN used for in cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e CYSTORELIN is used for the treatment of ovarian follicular cysts in milk-producing cattle and to synchronize estrous cycles in both lactating and beef cows. It supports fixed-time artificial insemination programs by stimulating hormone release that leads to ovulation and improved reproductive efficiency in managed herds.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does CYSTORELIN work in cattle reproduction?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e CYSTORELIN contains gonadorelin which is a synthetic hormone that functions similarly to the body’s natural GnRH produced in the hypothalamus. It acts on the anterior pituitary to trigger the release of important reproductive hormones such as luteinizing hormone and follicle-stimulating hormone, supporting ovulation and maintaining regular reproductive function in cattle when used under veterinary guidance.\u003c\/p\u003e\n\u003ch3\u003eQ3: What is the recommended dosage of CYSTORELIN?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The recommended dose is 2 ml per cow, providing 100 mcg of gonadorelin diacetate tetrahydrate. It may be given either intramuscularly or intravenously for treating cystic ovaries, and intramuscularly when used within estrus synchronization programs under veterinary guidance.\u003c\/p\u003e\n\u003ch3\u003eQ4: Is there a withdrawal period for milk or meat after using CYSTORELIN?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e There is no withdrawal period or milk discard time required when CYSTORELIN is used under veterinary supervision. This allows continued milk production and meat use without interruption, making it suitable for use in commercial dairy and beef cattle operations.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is CYSTORELIN safe for use in cattle?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e CYSTORELIN is safe for use in cattle. Research shows no major increase in health issues or negative effects on physiological parameters. It is overall well-tolerated when used according to the veterinary guidelines.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.proquest.com\/openview\/2029a66e8f565f59d2b0e615503652f9\/1?pq-origsite=gscholar\u0026amp;cbl=18750\" title=\"Induction of ovulation and lh response in cyclic mares treated with gonadorelin diacetate tetrahydrate - proquest\" aria-label=\"Visit a webpage about Induction of ovulation and lh response in cyclic mares treated with gonadorelin diacetate tetrahydrate - proquest\"\u003ehttps:\/\/www.proquest.com\/openview\/2029a66e8f565f59d2b0e615503652f9\/1?pq-origsite=gscholar\u0026amp;cbl=18750\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/bovine-ojs-tamu.tdl.org\/bovine\/article\/view\/124\" title=\"Case series: surgical treatment of non-responding diphtheria cases in feedlot cattle via long term tracheostomy | the bovine practitioner\" aria-label=\"Visit a webpage about Case series: surgical treatment of non-responding diphtheria cases in feedlot cattle via long term tracheostomy | the bovine practitioner\"\u003ehttps:\/\/bovine-ojs-tamu.tdl.org\/bovine\/article\/view\/124\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Merial","offers":[{"title":"30ml vial (15 dose)","offer_id":41785004359841,"sku":"11-04422","price":35.99,"currency_code":"USD","in_stock":true},{"title":"100ml vial (50 doses)","offer_id":45630564466849,"sku":"142120","price":103.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/cystorelin-sterile-solution-gonadorelin-diacetate-tetrahydrate-30ml-111.jpg?v=1778506581","url":"https:\/\/hordypaw.shop\/products\/cystorelin-sterile-solution-5ml","provider":"HardyPaw","version":"1.0","type":"link"}