{"product_id":"doxepin-50mg-capsules","title":"Doxepin Capsules, 50mg","description":"\u003cp\u003e\u003cimg width=\"700\" alt=\"RX MAP\" class=\"img-responsive\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003ePrescription Behavior and Allergy Capsules for Dogs and Cats\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eDoxepin HCl 50mg Capsules are a prescription tricyclic antidepressant with strong antihistamine properties used off-label by vets for dogs and cats. Working through dopamine and histamine receptor activity in the brain and body, it eases anxiety-driven behavioral issues and \u003ca rel=\"noopener\" href=\"\/en-ro\/collections\/dog-skin-medications\" target=\"_blank\" title=\"Dog skin irritation medications: anti-itch \u0026amp; allergy treatments | hardypaw\" aria-label=\"Dog skin irritation medications: anti-itch \u0026amp; allergy treatments | hardypaw\"\u003erelieves chronic allergic itching\u003c\/a\u003e at the same time. The 50mg strength suits medium-sized dogs needing a precise intermediate dose for anxiety, depression, compulsive disorders, or pruritic skin conditions.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnxiety and Depression Relief:\u003c\/strong\u003e Helps reduce depression, general anxiety, fear-based reactions, and noise phobia distress in dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChronic Itch Management:\u003c\/strong\u003e Brings antihistamine relief for long-lasting allergic itching and skin inflammation in pets that have not improved on standard treatments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompulsive Grooming Control:\u003c\/strong\u003e Reduces psychogenic overgrooming, excessive licking, and self-traumatic behavior driven by compulsive or anxiety-related disorders in pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDual-Action Formula:\u003c\/strong\u003e Goes after both central nervous system pathways and peripheral histamine receptors to handle behavioral and skin conditions together.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntermediate Dose Flexibility:\u003c\/strong\u003e The 50mg strength offers a practical middle-range option between lower and higher capsule strengths for accurate weight-based dosing.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eDoxepin Hydrochloride\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eDoxepin HCl 50mg Capsules are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking the capsule inside a soft pill pocket or pill wrap treat makes giving this medication easy and stress-free for both you and your pet. The capsule may be given with or without food, but if your pet experiences vomiting on an empty stomach, offer the capsule with a small meal going forward. Make sure your pet always has fresh water nearby while taking this medication.\u003c\/p\u003e\n\u003cp\u003e\u003ca aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" href=\"\/en-ro\/collections\/dog-pill-pockets\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" href=\"\/en-ro\/collections\/cat-pill-pockets\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid With MAOIs:\u003c\/strong\u003e Keep away from pets that received selegiline or amitraz in the past 14 days as a dangerous drug interaction can follow.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Amitraz Flea Collars:\u003c\/strong\u003e Amitraz tick and flea collars must never be worn during doxepin treatment due to the serious toxic interaction risk they carry.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Tyramine-Rich Foods:\u003c\/strong\u003e Aged cheeses and high-tyramine foods must stay off the menu completely as they can set off a dangerous blood pressure spike.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Glaucoma:\u003c\/strong\u003e Do not give to pets with glaucoma or urinary retention as doxepin can make both of these conditions noticeably worse over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Seizures:\u003c\/strong\u003e Use very carefully in pets with any prior seizure history as doxepin can lower the threshold at which seizures occur.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Thyroid Disease:\u003c\/strong\u003e Avoid in hyperthyroid pets as dangerous interactions between doxepin and elevated thyroid hormones can develop during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interaction Risk:\u003c\/strong\u003e Tell your vet if the pet takes cimetidine, fluoxetine, estrogens, sedatives, enalapril, verapamil, or ranitidine before starting doxepin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrowsiness and Sedation:\u003c\/strong\u003e Sleepiness tends to ease as the pet settles in; it is the most commonly reported reaction during doxepin treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDry Mouth and Constipation:\u003c\/strong\u003e Anticholinergic effects causing dry mouth and reduced bowel motility are commonly observed in pets receiving doxepin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlue-Green Urine:\u003c\/strong\u003e Urine may turn blue-green in some pets on doxepin; this is a harmless metabolic effect that clears up once treatment stops.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGI Upset and Excitability:\u003c\/strong\u003e Some pets get unusually wound up or have stomach issues like vomiting when first starting out on doxepin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Cardiac Effects:\u003c\/strong\u003e Overdosing can trigger dangerous heart rhythm problems that need emergency veterinary attention as soon as they appear.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep capsules in a sealed container at a steady temperature between 68°F and 77°F, well away from heat and moisture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Light:\u003c\/strong\u003e Sunlight and damp spots can break down the capsules over time, so keep them somewhere cool, dark, and dry.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Put this medication somewhere children and untreated pets cannot get to it on their own.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNote: \u003c\/strong\u003e\u003c\/span\u003eFor generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca aria-label=\"Shipping policy\" title=\"Shipping policy\" href=\"\/en-ro\/pages\/shipping-policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca aria-label=\"Refund policy\" title=\"Refund policy\" href=\"\/en-ro\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What makes doxepin an effective antihistamine for pets with allergic skin conditions?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Doxepin is one of the strongest H1 antihistamines in veterinary medicine, blocking histamine far more effectively than everyday options like diphenhydramine. Vets turn to it for pets stuck in a cycle of chronic allergic itching that has not budged with standard antihistamine options already tried.\u003c\/p\u003e\n\u003ch3\u003eQ2: Can doxepin be prescribed for cats with anxiety and overgrooming?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, doxepin is used off-label in cats for anxiety-driven overgrooming, psychogenic alopecia, and behavioral disorders. Cats process medications differently from dogs, so dosing for cats can look quite different. The vet sets the right amounts and intervals for each individual cat rather than applying standard dog dosing.\u003c\/p\u003e\n\u003ch3\u003eQ3: Does doxepin interact with any common flea and tick prevention products?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Amitraz-based flea and tick collars must never be used on pets taking doxepin as amitraz acts like an MAOI and the combination can turn dangerous. Most spot-on and oral options like fipronil, imidacloprid, and afoxolaner are safe, but always check with the vet before putting any new parasite product on a pet receiving doxepin.\u003c\/p\u003e\n\u003ch3\u003eQ4: How is the correct doxepin dose determined for a dog or cat?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The dose is based on body weight, with dogs typically getting anywhere from 0.25 to 2.5 mg per pound depending on what is being treated. The 50mg capsule tends to work well for medium-sized dogs. The vet works out the exact amount and picks the right capsule strength for each pet individually.\u003c\/p\u003e\n\u003ch3\u003eQ5: Should doxepin be tapered gradually when stopping treatment in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, stopping doxepin suddenly can bring on withdrawal effects like nausea, agitation, and behavioral shifts, so a gradual taper is the right approach. How long the taper takes depends on the dose and how long the pet has been on it. Never reduce or stop this medication without first checking with the vet.\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 capsule","offer_id":43320610095265,"sku":"477605-1","price":2.0,"currency_code":"RON","in_stock":true},{"title":"30 capsules","offer_id":44494914027681,"sku":"477605-30","price":53.0,"currency_code":"RON","in_stock":true},{"title":"60 capsules","offer_id":44494914060449,"sku":"477605-60","price":104.0,"currency_code":"RON","in_stock":true},{"title":"100 capsules","offer_id":43320610128033,"sku":"477605","price":159.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/doxepin-capsules-50mg-online-dog-pharmacy-supplements-vitamins-833.png?v=1778527659","url":"https:\/\/hordypaw.shop\/en-ro\/products\/doxepin-50mg-capsules","provider":"HardyPaw","version":"1.0","type":"link"}