{"product_id":"azathioprine-tablets-50mg","title":"Azathioprine Tablets for Dogs \u0026 Cats, 50mg","description":"\u003ch2\u003eImmunosuppressant Tablets for Autoimmune and Inflammatory Diseases in Dogs and Cats\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eAzathioprine 50mg Tablets are a prescription immunosuppressant used by veterinarians to treat serious autoimmune and inflammatory diseases in dogs and, with extreme caution, in cats. A purine analog, it converts in the body to active metabolites that shut down DNA and RNA synthesis in rapidly dividing immune cells, pulling the abnormal immune responses driving autoimmune disease under control. It is brought in alongside corticosteroids as a steroid-sparing agent, covering immune-mediated hemolytic anemia, inflammatory bowel disease, immune-mediated skin diseases, lupus, and rheumatoid arthritis. Ongoing blood count monitoring is mandatory throughout treatment.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAutoimmune Disease Management:\u003c\/strong\u003e Targets and suppresses abnormal immune cell activity behind immune-mediated hemolytic anemia, thrombocytopenia, and other autoimmune conditions in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSteroid-Sparing Agent:\u003c\/strong\u003e Lets corticosteroid doses come down gradually in dogs on long-term steroid therapy, reducing the cumulative toll of prolonged steroid use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammatory Bowel Disease Support:\u003c\/strong\u003e Brings chronic intestinal inflammation under control in dogs with IBD and colitis that have not responded adequately to diet or steroids alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune-Mediated Skin Disease:\u003c\/strong\u003e Goes after autoimmune skin conditions including pemphigus foliaceus and lupus erythematosus in dogs under specialist veterinary supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChronic Liver and Kidney Conditions:\u003c\/strong\u003e Used to manage certain immune-mediated hepatic and renal conditions in dogs where sustained immune suppression is part of the plan.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eAzathioprine 50mg\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eAzathioprine 50mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking this tablet into a soft pill pocket or pill wrap treat is a simple way to get your pet to take their daily dose.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en-ro\/collections\/dog-pill-pockets\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/en-ro\/collections\/cat-pill-pockets\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassified as Hazardous Drug:\u003c\/strong\u003e Azathioprine is NIOSH-classified as a hazardous drug and requires disposable gloves for every handling, with no crushing or splitting without protection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtreme Caution in Cats:\u003c\/strong\u003e Cats face a serious risk of fatal bone marrow suppression with azathioprine and should only receive it at very low doses under specialist supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCritical Allopurinol Interaction:\u003c\/strong\u003e Allopurinol blocks the breakdown of azathioprine's toxic metabolite, pushing it to dangerous levels and creating a potentially fatal interaction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Stop Abruptly:\u003c\/strong\u003e Tapering off gradually over several months under veterinary direction is essential, as sudden discontinuation can set off a dangerous autoimmune rebound.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Pregnancy and Breeding:\u003c\/strong\u003e Pregnant, lactating, or breeding animals should not receive this medication given its serious teratogenic and reproductive toxicity potential.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Liver and Pancreatic Disease:\u003c\/strong\u003e Pets with liver or pancreatic disease need careful management, as azathioprine is processed by the liver and can make these conditions worse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMandatory Blood Count Monitoring:\u003c\/strong\u003e Complete blood count and platelet monitoring every one to two weeks for the first three months, then monthly after that, is non-negotiable for safe use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone Marrow Suppression:\u003c\/strong\u003e Falling white cell, red cell, and platelet counts are the most dangerous reaction and require regular monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Upset:\u003c\/strong\u003e Vomiting, diarrhea, and reduced appetite are frequently seen and tend to ease when given with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Toxicity:\u003c\/strong\u003e Jaundice or abdominal pain pointing to hepatotoxicity or pancreatitis needs immediate veterinary assessment without delay.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Infection Risk:\u003c\/strong\u003e With immune suppression dialing back the body's defenses, bacterial, viral, and fungal infections become harder to fight off and may need additional treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLong-Term Cancer Risk:\u003c\/strong\u003e As with all immunosuppressants, very prolonged use carries a theoretical elevated risk of certain cancers over time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eControlled Room Temperature:\u003c\/strong\u003e These tablets should be best kept between 59°F and 77°F, inside a sealed container where heat and humidity cannot reach them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Light and Moisture:\u003c\/strong\u003e Direct sunlight and damp conditions can chip away at the tablet's potency, so a dry, shaded storage spot is the right choice.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOut of Reach:\u003c\/strong\u003e Keep this medication in a secure, locked location where children and untreated animals in the home cannot get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNOTE: \u003c\/strong\u003e\u003c\/span\u003eFor generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What autoimmune conditions does azathioprine treat in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dogs are treated for immune-mediated hemolytic anemia, thrombocytopenia, IBD, colitis, pemphigus, lupus, rheumatoid arthritis, and certain kidney and liver diseases with it. Cats are a different story, with use confined to severe autoimmune skin conditions at much lower doses under specialist supervision.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why is azathioprine considered a steroid-sparing agent in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Long-term corticosteroid use for autoimmune disease builds up a significant cumulative toll through muscle wasting, diabetes, and immune compromise. Bringing azathioprine into the plan lets the steroid dose come down gradually without losing control of the disease. The combination keeps the autoimmune condition in check while reducing how much steroid the dog is actually carrying.\u003c\/p\u003e\n\u003ch3\u003eQ3: Why is azathioprine used with extreme caution in cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cats are far more sensitive to azathioprine's bone marrow effects than dogs, and many specialists use chlorambucil instead for that reason. When it is used in cats, the dose stays very low and blood counts need careful monitoring throughout.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why must allopurinol never be given alongside azathioprine?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Once inside the body, azathioprine becomes 6-mercaptopurine, and allopurinol prevents that metabolite from clearing. The accumulation puts the bone marrow at fatal risk. A dog on allopurinol for urate stones or leishmaniasis should have that flagged to a veterinarian before azathioprine enters the picture.\u003c\/p\u003e\n\u003ch3\u003eQ5: What blood count monitoring schedule is required for dogs on azathioprine?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Complete blood counts run every one to two weeks for the first three months, then monthly once values are steady. Liver enzyme checks are part of the routine too. A concerning shift in either direction is reason to adjust the dose or reconsider the medication.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/meridian.allenpress.com\/jaaha\/article-abstract\/60\/3\/105\/500367\/Filgrastim-Use-in-the-Treatment-of-Azathioprine\" title=\"Https:\/\/meridian.allenpress.com\/jaaha\/article-abstract\/60\/3\/105\/500367\/filgrastim-use-in-the-treatment-of-azathioprine\" aria-label=\"Visit a webpage about Https:\/\/meridian.allenpress.com\/jaaha\/article-abstract\/60\/3\/105\/500367\/filgrastim-use-in-the-treatment-of-azathioprine\"\u003ehttps:\/\/meridian.allenpress.com\/jaaha\/article-abstract\/60\/3\/105\/500367\/Filgrastim-Use-in-the-Treatment-of-Azathioprine\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Varies (Generic)","offers":[{"title":"1 tablet","offer_id":44280078532769,"sku":"197806-1","price":4.0,"currency_code":"RON","in_stock":true},{"title":"30 tablets","offer_id":44280078598305,"sku":"197806-30","price":89.0,"currency_code":"RON","in_stock":true},{"title":"60 tablets","offer_id":44280078631073,"sku":"197806-60","price":168.0,"currency_code":"RON","in_stock":true},{"title":"100 tablets","offer_id":44280078663841,"sku":"197806","price":289.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/azathioprine-tablets-for-dogs-cats-50mg-pet-medicine-261.png?v=1778507252","url":"https:\/\/hordypaw.shop\/en-ro\/products\/azathioprine-tablets-50mg","provider":"HardyPaw","version":"1.0","type":"link"}