{"product_id":"amantadine-100mg-capsules","title":"Amantadine (Generic) Capsules, 100mg","description":"\u003cp align=\"center\"\u003e\u003cimg loading=\"lazy\" data-files=\"rx-map.jpg\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" width=\"700\" alt=\"RX MAP\" class=\"img-responsive\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\"\u003e\u003c\/p\u003e\n\u003ch2\u003eNMDA Receptor Blocker Capsules for Chronic and Neuropathic Pain in Pets\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eAmantadine HCl 100mg Capsules are a prescription NMDA receptor antagonist used by veterinarians to \u003ca href=\"\/en-ro\/collections\/dog-arthritis-medications\" target=\"_blank\" rel=\"noopener\" title=\"Dog arthritis medication: treat inflammation \u0026amp; joint pain | hardypaw\" aria-label=\"Dog arthritis medication: treat inflammation \u0026amp; joint pain | hardypaw\"\u003emanage chronic and neuropathic pain in dogs\u003c\/a\u003e and cats. It works by shutting off NMDA receptors in the central nervous system that turn up the volume on pain signals and drive the cycle of wind-up pain. It works best alongside other analgesics like NSAIDs, giving their pain-relieving effect a meaningful boost. It is commonly prescribed for osteoarthritis, neuropathic pain, osteosarcoma pain, and post-surgical recovery, and is used off-label in veterinary medicine.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eChronic Pain Relief:\u003c\/strong\u003e Addresses persistent pain from osteoarthritis, neuropathy, and other chronic conditions in dogs and cats that have not responded well to standard pain medications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhances Other Analgesics:\u003c\/strong\u003e Gives NSAIDs and other pain medications a significant lift in effectiveness when used alongside them as part of a multimodal pain plan.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCancer Pain Support:\u003c\/strong\u003e Helps manage pain tied to osteosarcoma and other painful cancers in dogs and cats under ongoing veterinary supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-Sedating Pain Relief:\u003c\/strong\u003e Unlike opioids and similar analgesics, amantadine does not bring on sedation, so pets stay alert and active throughout treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-Surgical Recovery:\u003c\/strong\u003e Given after declaw procedures and other surgeries to address neuropathic pain and help pets recover more comfortably.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eAmantadine Hydrochloride\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eAmantadine HCl 100mg Capsules are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking this capsule into a soft pill pocket or pill wrap treat is a simple way to get your pet to take their full daily dose without any trouble. This medication can be given with or without food, but keeping fresh water available throughout the day is a good habit to maintain.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en-ro\/collections\/dog-pill-pockets\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/en-ro\/collections\/cat-pill-pockets\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Kidney Disease:\u003c\/strong\u003e Pets with kidney disease should not receive this medication, as it clears through the kidneys and can reach toxic levels when renal function is reduced.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Seizure Disorders:\u003c\/strong\u003e Pets with a history of seizures should not be given this medication, as it may bring the seizure threshold down and make the condition worse.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Glaucoma:\u003c\/strong\u003e Pets with untreated glaucoma should not receive this medication, as it may push intraocular pressure higher.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Pregnancy and Breeding:\u003c\/strong\u003e Pregnant, lactating, or breeding animals should not be given this medication, as its safety in these situations has not been established.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Liver Disease and Heart Failure:\u003c\/strong\u003e Pets with liver dysfunction or congestive heart failure need careful management, as these conditions can change how the drug is handled in the body.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Stop Abruptly:\u003c\/strong\u003e Stopping this medication without a gradual taper can cause problems, so always work with a veterinarian when reducing or ending treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interaction Risk:\u003c\/strong\u003e Trimethoprim-sulfa antibiotics, quinidine, and thiazide diuretics should not be used alongside this medication without specific veterinary guidance on handling those interactions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlatulence and Diarrhea:\u003c\/strong\u003e Gas and loose stools are among the more commonly seen reactions and tend to be mild and short-lived in most pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAgitation and Restlessness:\u003c\/strong\u003e Some pets show signs of behavioral agitation or restlessness, particularly when first starting or at higher doses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDifficulty Urinating:\u003c\/strong\u003e Combined with antihistamines, this medication can bring on urinary retention, dry mouth, and a faster heart rate in some pets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOverdose Signs:\u003c\/strong\u003e Agitation, confusion, balance problems, a racing heart, labored breathing, and seizures all point to a potentially fatal overdose needing immediate emergency veterinary care.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eControlled Room Temperature:\u003c\/strong\u003e Store capsules somewhere cool and dry, maintaining a temperature of 59°F to 86°F and keeping them away from heat and moisture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Moisture and Light:\u003c\/strong\u003e Humid conditions and direct sunlight can wear down the capsule's potency, so a dry, shaded storage spot is the right choice.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOut of Reach:\u003c\/strong\u003e Keep this medication somewhere children and untreated animals in the home cannot get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003eNOTE:\u003c\/span\u003e\u003c\/strong\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What conditions does amantadine treat in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Amantadine is used for chronic pain from osteoarthritis, neuropathic pain, osteosarcoma-related cancer pain, and post-surgical recovery including declaw procedures. It is especially useful for pets that have not responded well enough to NSAIDs on their own and is typically paired with other pain medications for a well-rounded approach.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does amantadine relieve pain differently from NSAIDs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e NSAIDs go after inflammation at the injury site, while amantadine takes on NMDA receptors in the central nervous system that amplify and keep pain going. That directly tackles wind-up pain, where ongoing nerve activity causes the body to feel pain more intensely than it should. Hitting different parts of the pain pathway is what makes the two so effective in combination.\u003c\/p\u003e\n\u003ch3\u003eQ3: How long does amantadine take to work in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e It generally takes around 7 to 10 days of steady daily dosing before the full pain-relieving effect comes through. Improvements in how the pet moves, how comfortable they seem, and how active they are tend to become noticeable within the first couple of weeks. Completing the full course and checking with a veterinarian before stopping is important.\u003c\/p\u003e\n\u003ch3\u003eQ4: Can amantadine be used as the sole pain medication for pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Amantadine on its own is generally not enough to manage pain effectively and is usually prescribed alongside NSAIDs or other analgesics. Its real value is in boosting what other pain medications can do and tackling the central sensitization that standard analgesics tend to leave unaddressed. A veterinarian will put together the right combination for each pet.\u003c\/p\u003e\n\u003ch3\u003eQ5: What are the signs of an amantadine overdose in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Agitation, confusion, behavioral shifts, loss of balance, labored breathing, a racing heart, and seizures are all warning signs of a potentially fatal overdose. Getting professional help immediately is critical if an excessive dose is suspected, so call a veterinarian or emergency clinic without delay rather than waiting to see how the pet responds.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/link.springer.com\/article\/10.1007\/s40262-018-0663-4?error=cookies_not_supported\u0026amp;code=67b7c1be-7bb5-4022-880c-9409c187fe13\" title=\"Pharmacokinetics of ads-5102 (amantadine) extended release capsules administered once daily at bedtime for the treatment of dyskinesia | clinical pharmacokinetics | springer nature link\" aria-label=\"Visit a webpage about Pharmacokinetics of ads-5102 (amantadine) extended release capsules administered once daily at bedtime for the treatment of dyskinesia | clinical pharmacokinetics | springer nature link\"\u003ehttps:\/\/link.springer.com\/article\/10.1007\/s40262-018-0663-4\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1098612X20967639\" title=\"Https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1098612x20967639\" aria-label=\"Visit a webpage about Https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1098612x20967639\"\u003ehttps:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1098612X20967639\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jvp.12190\" title=\"Https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jvp.12190\" aria-label=\"Visit a webpage about Https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jvp.12190\"\u003ehttps:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jvp.12190\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Varies (Generic)","offers":[{"title":"1 capsule","offer_id":43330343633057,"sku":"518006-1","price":2.0,"currency_code":"RON","in_stock":true},{"title":"30 capsules","offer_id":44425946759329,"sku":"518006-30","price":41.0,"currency_code":"RON","in_stock":true},{"title":"60 capsules","offer_id":44425946792097,"sku":"518006-60","price":82.0,"currency_code":"RON","in_stock":true},{"title":"100 capsules","offer_id":43330343665825,"sku":"518006","price":131.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/amantadine-generic-capsules-100mg-100-pet-medicine-979.png?v=1778528023","url":"https:\/\/hordypaw.shop\/en-ro\/products\/amantadine-100mg-capsules","provider":"HardyPaw","version":"1.0","type":"link"}