{"product_id":"advantage-multi-topical-solution-for-dogs-55-1-88-lbs","title":"Advantage Multi Topical Solution for Dogs 55.1-88 lbs, Blue","description":"\u003ch2\u003eMonthly Topical 6-in-1 Parasite Protection for Large Dogs (55.1–88 lbs)\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eAdvantage Multi Topical Solution (Blue) is a prescription monthly spot-on for dogs and puppies between 55.1 and 88 pounds. It pairs Imidacloprid (10%) with Moxidectin (2.5%) to fight six parasites in one monthly tube. It covers heartworm prevention, flea control, sarcoptic mange, and intestinal worms including roundworms, hookworms, and whipworms. Dogs and puppies from 7 weeks old, weighing a minimum of 3 pounds, can be treated with this product.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevents Heartworm Disease:\u003c\/strong\u003e Moxidectin gets absorbed through the skin and keeps working all month, giving large dogs steady protection against heartworm larvae.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduces Microfilariae Levels:\u003c\/strong\u003e One of the few topical preventives that helps lower circulating heartworm microfilariae in dogs already testing positive for the infection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKills Fleas on Contact:\u003c\/strong\u003e Imidacloprid travels through the skin's natural oil layer and kills adult fleas before they ever get the chance to bite your dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStops Flea Infestations:\u003c\/strong\u003e Re-infesting fleas die within 3 to 5 minutes of contact, and egg-laying is disrupted, keeping full-blown infestations from taking hold.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eControls Sarcoptic Mange:\u003c\/strong\u003e Targets the mites behind sarcoptic mange, which large dogs often pick up at grooming facilities, dog parks, or boarding kennels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClears Roundworm Infections:\u003c\/strong\u003e Takes care of adult Toxocara canis and Toxascaris leonina roundworm infections in large dogs with each monthly dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClears Hookworm Infections:\u003c\/strong\u003e Works against Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala hookworms at multiple stages of their life cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClears Whipworm Infections:\u003c\/strong\u003e Also handles Trichuris vulpis whipworm infections, rounding out full intestinal parasite coverage in one spot-on application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHolds Up Against Water:\u003c\/strong\u003e Protection stays effective 60 minutes after your dog goes for a swim and 90 minutes after a bath, great for active large breeds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible if a Dose is Late:\u003c\/strong\u003e If you miss the monthly window by a few days, simply apply right away and continue your regular monthly schedule from there.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafe From 7 Weeks Old:\u003c\/strong\u003e Cleared for use in puppies as young as 7 weeks, provided they weigh at least 3 pounds at the time of application.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 61.6232%; height: 59px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 24.6607%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75.0621%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity (per tube, 55.1–88 lb dogs)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 24.6607%; height: 19.6023px;\"\u003eImidacloprid\u003c\/td\u003e\n\u003ctd style=\"width: 75.0621%; height: 19.6023px;\"\u003e400 mg (10%)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 24.6607%; height: 19.6023px;\"\u003eMoxidectin\u003c\/td\u003e\n\u003ctd style=\"width: 75.0621%; height: 19.6023px;\"\u003e100 mg (2.5%)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eTotal volume: 4 mL\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDirections for Use\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Only:\u003c\/strong\u003e This is an FDA-licensed prescription product and can only be dispensed through or under the direction of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApply Once a Month:\u003c\/strong\u003e Empty the full contents of one tube onto your dog's skin once every month, ideally on the same date each time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCorrect Monthly Dose:\u003c\/strong\u003e The right amount is at least 4.5 mg\/lb (10 mg\/kg) imidacloprid and 1.1 mg\/lb (2.5 mg\/kg) moxidectin per application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 1 – Open the Tube:\u003c\/strong\u003e Take one applicator tube out of the packaging. Keep it pointing upward and pull the cap off.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 2 – Break the Seal:\u003c\/strong\u003e Flip the cap around and press its other end firmly onto the tip of the tube. Twist until the seal breaks, then remove the cap fully.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 3 – Find the Right Spot:\u003c\/strong\u003e Ask your dog to stand still. Separate the fur between the shoulder blades until you can see the skin clearly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 4 – Apply Along the Back:\u003c\/strong\u003e Press the tip against the skin and squeeze the full contents across three or four spots along the backline, starting at the base of the neck and moving toward the upper back. Choose spots your dog cannot reach to lick. Do not apply so much in one spot that it drips off the side.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkip Broken or Irritated Skin:\u003c\/strong\u003e Do not apply the solution to any area of skin that is cut, raw, or inflamed in any way.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Mange Treatment:\u003c\/strong\u003e A single monthly dose is the standard approach; your veterinarian may recommend a second application the following month if needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Over 110 lbs:\u003c\/strong\u003e Your veterinarian will advise on the right combination of tubes to reach the correct total dose for your dog's weight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf You Miss a Dose:\u003c\/strong\u003e Apply as soon as you remember and carry on with the regular monthly schedule from that point; never apply two doses at once.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any medication for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm Test First:\u003c\/strong\u003e Dogs should be screened for heartworm before the first dose is given, since adult heartworm infections are not addressed by this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdult Heartworms Not Treated:\u003c\/strong\u003e This product does not kill adult heartworms; dogs with a positive diagnosis should receive adulticide therapy before beginning use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Give by Mouth:\u003c\/strong\u003e Swallowing this solution can cause serious harm including tremors, incoordination, excessive drooling, and dilated pupils in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevent Licking After Application:\u003c\/strong\u003e Keep your dog from reaching its own treated area or another treated pet's skin for a minimum of 30 minutes post-application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Children at a Distance:\u003c\/strong\u003e Children should not touch the treated area of skin for at least two hours after the product has been applied.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This formulation must not be used on cats; a separate cat-specific version of this product is available through your veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect the Eyes:\u003c\/strong\u003e If the solution makes contact with the eyes, hold the eyelids open, rinse well with water, and speak with your veterinarian promptly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Age and Weight:\u003c\/strong\u003e This product has not been found safe for puppies or dogs younger than 7 weeks or weighing under 3 pounds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Unwell Dogs:\u003c\/strong\u003e Sick, underweight, or weakened large dogs need extra consideration before use; check with your veterinarian before applying.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding and Lactating Dogs:\u003c\/strong\u003e No safety data exists for pregnant or nursing dogs; your veterinarian should assess the risk before use in these animals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGap Before Adulticide Treatment:\u003c\/strong\u003e Using this product on the same day as heartworm adulticide therapy has not been studied; your veterinarian should set the timing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWorm Counts Can Vary:\u003c\/strong\u003e In a small number of heartworm-positive dogs, microfilariae levels may not drop as expected; regular veterinary monitoring remains essential.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClean Hands After Use:\u003c\/strong\u003e Wash your hands well with soap and water every time you finish applying the product to your dog.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Reactions at Application Site:\u003c\/strong\u003e Mild itching, flaking, or visible residue around where the product was applied can occur and usually clears up on its own.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStomach-Related Signs:\u003c\/strong\u003e Some dogs may show loose stools, vomiting, reduced appetite, or traces of blood in their stool after receiving treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Energy:\u003c\/strong\u003e Some dogs appear more tired than usual or sleep longer periods following their monthly application of this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnusual Behaviour:\u003c\/strong\u003e Restlessness, excessive self-grooming, hiding, or pacing has been reported after application; speak to your vet if it continues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIf the Product is Swallowed:\u003c\/strong\u003e Licking the treated area can lead to serious neurological signs; take your dog to an emergency vet without delay if this happens.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Infection Near the Site:\u003c\/strong\u003e In some cases, a skin infection (pyoderma) developed at or close to where the product was applied during field safety testing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRare but Serious Reactions:\u003c\/strong\u003e Sudden facial swelling, hives, pale gums, seizures, or collapse are uncommon but require urgent emergency veterinary care.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExcess Drooling:\u003c\/strong\u003e Some dogs produce more saliva than usual within the first hour of treatment; let your vet know if this does not settle down.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCorrect Temperature Range:\u003c\/strong\u003e Keep stored between 39°F (4°C) and 77°F (25°C); do not let the product freeze or sit in excessive heat.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOut of Reach at All Times:\u003c\/strong\u003e Store this prescription medication somewhere children and other pets cannot access it to avoid accidental exposure.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What parasites does Advantage Multi (Blue) protect large dogs against?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Advantage Multi (Blue) covers six parasites in one tube: heartworm larvae, circulating microfilariae in already-infected dogs, adult fleas, flea infestations, sarcoptic mange mites, and intestinal worms including roundworms, hookworms, and whipworms. It does not cover ticks.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the Blue Box for 55.1–88 lb dogs differ from the Red Box for smaller dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The Blue Box holds 400 mg imidacloprid and 100 mg moxidectin in a 4 mL tube. The Red Box holds 250 mg and 62.5 mg in a 2.5 mL tube. Both provide the same protection. Always pick the box that fits your dog's current weight.\u003c\/p\u003e\n\u003ch3\u003eQ3: How does this spot-on treatment compare to oral heartworm preventives for large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This topical solution absorbs through the skin and provides month-long heartworm protection without a tablet. It also handles fleas, intestinal worms, and sarcoptic mange in the same application, and it is one of the few products that can reduce microfilariae levels in heartworm-positive dogs.\u003c\/p\u003e\n\u003ch3\u003eQ4: What should I do if my large dog licks the treated area?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Swallowing this product can cause muscle tremors, poor coordination, drooling, and dilated pupils. Get your dog to a veterinarian or emergency clinic straight away. After applying, keep your dog away from the treated spot for at least 30 minutes and separate it from other pets during that time.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Advantage Multi (Blue) safe to use if my large dog has already been diagnosed with heartworms?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This product cannot kill adult heartworms. Dogs with a confirmed infection should complete adulticide treatment first. However, it is one of the few topicals indicated to reduce microfilariae in heartworm-positive dogs. Your veterinarian should plan the timing of both treatments carefully.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a\" title=\"Dailymed - advantage multi for dogs- imidacloprid, moxidectin solution\" aria-label=\"Visit a webpage about Dailymed - advantage multi for dogs- imidacloprid, moxidectin solution\"\u003ehttps:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/804\" title=\"Https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadfoi\/804\" aria-label=\"Visit a webpage about Https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadfoi\/804\"\u003ehttps:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/804\u003c\/a\u003e\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"1 month","offer_id":44249909592225,"sku":"90209558-1","price":110.0,"currency_code":"RON","in_stock":true},{"title":"6 months","offer_id":44249909624993,"sku":"90209558","price":660.0,"currency_code":"RON","in_stock":true},{"title":"12 months","offer_id":44249909657761,"sku":"90209558-PK2","price":1319.0,"currency_code":"RON","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/advantage-multi-topical-solution-for-dogs-55-1-88-lbs-blue-6-months-393.jpg?v=1778102108","url":"https:\/\/hordypaw.shop\/en-ro\/products\/advantage-multi-topical-solution-for-dogs-55-1-88-lbs","provider":"HardyPaw","version":"1.0","type":"link"}