{"title":"All Cushing’s Disease Medication","description":"","products":[{"product_id":"prascend-tablets-for-horses-1-mg","title":"Prascend Pergolide for Horses - 1 mg Tablets","description":"\u003ch2\u003e\u003cstrong\u003eControls PPID Symptoms in Horses\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003ePRASCEND is an FDA-approved oral tablet formulated for horses diagnosed with Pituitary Pars Intermedia Dysfunction, commonly known as Equine Cushing’s Disease. It contains pergolide mesylate, a dopamine receptor agonist that helps regulate hormone levels linked to PPID. Daily administration supports improvement in clinical signs such as hirsutism, abnormal fat distribution, and muscle wasting when used as directed by a veterinarian.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHormone Level Regulation Aid:\u003c\/strong\u003e Designed to help bring elevated ACTH levels closer to normal in PPID affected horses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinical Symptom Management: \u003c\/strong\u003eHelps address long coats, excessive sweating, muscle thinning, and unusual fat deposits.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDocumented Treatment Results: \u003c\/strong\u003eProven effectiveness observed in more than three out of four horses by Day 180.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdaptable Dosage Approach:\u003c\/strong\u003e Dosage can be fine tuned based on lab results and the horse’s clinical response.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAvailable in 3 sizes: \u003c\/strong\u003e1 Tablet,  60 tablets, and 160 tablets.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eActive Ingredients\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003ePergolide mesylate 1 mg per tablet\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable height=\"122\" style=\"width: 73.5714%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e\u003cstrong\u003eBody Weight\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e2 mcg per kg\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e\u003cstrong\u003e4 mcg per kg\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e136 to 340 kg (300 to 749 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e0.5 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e341 to 567 kg (750 to 1,249 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e1 tablet\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e2 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e568 to 795 kg (1,250 to 1,749 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e1.5 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e3 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd width=\"264\" style=\"width: 46.7509%;\"\u003e\n\u003cp\u003e796 to 1,022 kg (1,750 to 2,249 lb)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"160\" style=\"width: 28.3394%;\"\u003e\n\u003cp\u003e2 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"153\" style=\"width: 24.1877%;\"\u003e\n\u003cp\u003e4 tablets\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eDisclaimer: \u003c\/em\u003e\u003c\/strong\u003e\u003cem\u003eThis dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/em\u003e\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eApproved Starting Dose: \u003c\/strong\u003eIs labeled for an initial dosage of 2 mcg per kg body weight once daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustment Range: \u003c\/strong\u003eDosage is approved for adjustment based on endocrine testing response, not exceeding 4 mcg per kg daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTablet Scoring: \u003c\/strong\u003eTablets are scored and labeled to allow dosing to the nearest one-half tablet increment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Status: \u003c\/strong\u003eFederal law restricts this product to use by or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Use: \u003c\/strong\u003eThe manufacturer has not evaluated or confirmed the safety of this product for use in breeding horses, pregnant mares, or lactating animals.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions: \u003c\/strong\u003eUsing this medication alongside dopamine antagonists may lessen its effectiveness because the drugs work against each other pharmacologically.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtein Binding: \u003c\/strong\u003ePergolide binds strongly to proteins, so extra care is needed when it is given with other medications that also have high protein-binding properties.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHuman Exposure: \u003c\/strong\u003eTo reduce the risk of accidental human exposure during handling, the tablets should not be crushed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDecreased Appetite: \u003c\/strong\u003eInappetence was commonly reported, particularly during the first month of treatment in clinical studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Signs: \u003c\/strong\u003eColic and loose stool have been reported during both pre-approval and post-approval monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavior Changes: \u003c\/strong\u003eBehavioral effects such as agitation, aggression, or increased activity have been observed in some horses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaminitis Risk: \u003c\/strong\u003eBoth new and recurring cases of laminitis were reported during clinical safety evaluations.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage Temperature Guideline: \u003c\/strong\u003eThe product should be kept at temperatures no higher than 25°C or 77°F to maintain quality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Storage: \u003c\/strong\u003eMust be stored securely to prevent accidental ingestion by dogs, cats, or other animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is PRASCEND used for in horses?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PRASCEND is approved by the FDA to help manage clinical signs linked to Pituitary Pars Intermedia Dysfunction in horses. When used with veterinary guidance, it helps address hormone-driven concerns such as long or abnormal hair growth, uneven fat buildup, muscle loss, and other signs commonly seen with PPID.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How does PRASCEND work in horses with PPID?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PRASCEND contains \u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Pergolide-Mesylate\" target=\"_blank\" rel=\"noopener\" title=\"Pergolide mesylate | c20h30n2o3s2 | cid 47812 - pubchem\" aria-label=\"Visit a webpage about Pergolide mesylate | c20h30n2o3s2 | cid 47812 - pubchem\"\u003epergolide mesylate\u003c\/a\u003e, a dopamine receptor agonist. In horses with PPID, it helps stimulate dopamine receptors, which have been shown to reduce elevated ACTH and other related hormone levels involved in the disease process.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: Is PRASCEND a prescription medication?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes, PRASCEND is a prescription-only veterinary medication. Federal law restricts its use to horses treated by or on the order of a licensed veterinarian, ensuring appropriate diagnosis, dosing oversight, and ongoing monitoring during treatment.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: What are the common side effects reported with PRASCEND?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The most commonly reported side effects include decreased appetite, lethargy, diarrhea, colic, behavioral changes, and laminitis. Many cases were transient and occurred early in treatment, though post-approval reports indicate effects may also occur after dose adjustments.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: How should PRASCEND be stored?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns: \u003c\/strong\u003ePRASCEND tablets should be stored at temperatures of 25°C or 77°F or lower. Keep the product in a safe place to avoid accidental access by dogs, cats, or other animals. \u003c\/p\u003e","brand":"Boehringer Ingelheim","offers":[{"title":"160 Tablets","offer_id":41235863011489,"sku":"131356","price":432.99,"currency_code":"USD","in_stock":true},{"title":"60 Tablets","offer_id":41235863044257,"sku":"139668","price":190.0,"currency_code":"USD","in_stock":true},{"title":"1 Tablet","offer_id":41235863077025,"sku":"139668-1","price":2.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/prascend-pergolide-for-horses-1-mg-tablets-pet-medicine-714.webp?v=1778035089"},{"product_id":"dechra-vetoryl-capsules-for-dogs-5mg","title":"Vetoryl Capsules (Trilostane) for Dogs, 5mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 5 mg is an FDA-approved, prescription-only oral treatment for Cushing's disease in dogs. Each capsule holds 5 mg of trilostane, a synthetic steroid analogue that brings cortisol production in the adrenal cortex under control. Given once daily with food, it manages both pituitary-dependent and adrenal-dependent forms of the condition and is the smallest strength in the range, making it the natural starting point for toy breeds and very small dogs.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Effective for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, the two most frequently diagnosed forms of Cushing's disease in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e By reversibly blocking 3-beta-hydroxysteroid dehydrogenase in the adrenal cortex, trilostane reduces the overproduction of cortisol right at its source.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e Most dogs in clinical field studies showed measurable improvement in thirst, urination, and panting within the first 14 days of therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e One oral dose each day is all that is needed, making it simple to build into a long-term daily care routine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIdeal Starter Strength:\u003c\/strong\u003e As the smallest available Vetoryl dose, the 5 mg capsule is the go-to choice for toy breeds and very small dogs beginning trilostane therapy for the first time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Trilostane's cortisol-reducing effect can be reversed, so your veterinarian can safely adjust or stop treatment as your dog's needs change over time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 45.0597%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 39.4211%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 60.1217%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 39.4211%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 60.1217%; height: 19.6023px;\"\u003e5 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US Federal law limits this medication to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This medication is for oral use in dogs only and must never be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Your veterinarian will work out the appropriate starting dose for your dog based on body weight and individual health needs before prescribing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e Give one dose each morning with food to support proper absorption and reduce the likelihood of digestive upset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the Capsule Whole:\u003c\/strong\u003e Never break open, empty, or divide the capsule; it should always be given intact as your vet or pharmacist dispensed it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Check-In:\u003c\/strong\u003e Plan for a vet visit around 10 to 14 days after starting, where an ACTH stimulation test and full biochemistry panel will be carried out.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e Changes to the dose are made based on test results and how your dog is doing clinically; never adjust the dose without your veterinarian's direction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch for Warning Signs:\u003c\/strong\u003e If your dog vomits, has diarrhea, seems unusually tired, loses interest in food, becomes weak, or collapses, stop the medication right away and call your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Wash your hands thoroughly with soap and water each time you handle the capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Do not use in dogs with a known allergic reaction or sensitivity to trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Dogs with liver or kidney problems are not suitable candidates; both organ systems should be evaluated before treatment starts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Trilostane has been associated with birth defects and early pregnancy loss in animal studies; it must never be used in pregnant dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Anyone who is pregnant or trying to conceive should avoid all contact with these capsules given the known teratogenic risk of trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression:\u003c\/strong\u003e Addison's disease can develop regardless of the dose used; some dogs need months to recover normal adrenal function and some may not recover fully at all.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Medications:\u003c\/strong\u003e Take extra care if your dog is on any heart medication; inform your vet of everything your dog is currently taking before beginning treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevious Mitotane Use:\u003c\/strong\u003e At least one full month must pass after stopping mitotane, and ACTH levels must be back to normal, before Vetoryl therapy can begin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e The safety profile in nursing females and males used for breeding has not been established; always check with your vet before using in these animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e A drop in appetite and vomiting are the most commonly reported reactions; if your dog experiences either, pause the medication and get in touch with your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Tiredness, reduced interest in activity, and general physical weakness have been consistently reported across clinical and post-market data.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose or watery stools have been noted in some dogs; keep an eye on bowel habits and report anything unusual to your veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Some dogs show rises in liver enzyme levels; this is another reason why regular bloodwork matters throughout treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Changes in potassium and sodium balance can signal that adrenal suppression has gone too far and needs to be addressed quickly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e Rare but serious outcomes including kidney failure and Addison's disease have in some cases been fatal; get veterinary help immediately if your dog suddenly worsens or collapses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at around 25°C (77°F), away from moisture and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication somewhere children and other animals simply cannot get to.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 5 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl 5 mg treats hyperadrenocorticism, more commonly known as Cushing's disease, in dogs. It is effective for both the pituitary-dependent type, which is the most frequently seen form, and the adrenal-dependent type, where excess cortisol stems from a growth on the adrenal gland.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does trilostane in Vetoryl work to control Cushing's disease?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Trilostane reversibly blocks 3-beta-hydroxysteroid dehydrogenase, the enzyme that drives cortisol production in the adrenal cortex. By interrupting this step, it reduces the amount of cortisol the body produces, easing the hormonal overload that causes the symptoms of Cushing's disease in dogs.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 5 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Most dogs in clinical studies showed clear signs of improvement within 14 days of starting Vetoryl. Owners typically noticed less thirst, fewer bathroom trips, and reduced panting fairly early on. A follow-up ACTH stimulation test is usually booked for the 10 to 14 day mark to check how the dose is performing.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my dog need regular testing while on Vetoryl 5 mg?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Regular testing matters because even a low dose can sometimes suppress adrenal function more than intended, leading to Addison's disease. Routine ACTH stimulation tests and biochemistry panels keep cortisol within a safe range and help your vet catch any concerning shifts before they become serious.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Vetoryl (Trilostane) 5 mg a cure for Cushing's disease in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl controls the condition by lowering cortisol production but does not remove the underlying cause. When treatment stops, cortisol levels rise again and symptoms return, which is why the vast majority of dogs with Cushing's disease remain on this medication for life.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\" title=\"Https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\" aria-label=\"Visit a webpage about Https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\"\u003ehttps:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5855282\/\" title=\"Update on the use of trilostane in dogs - pmc\" aria-label=\"Visit a webpage about Update on the use of trilostane in dogs - pmc\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5855282\/\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44488063647905,"sku":"VET-005","price":74.57,"currency_code":"USD","in_stock":true},{"title":"60 Capsules","offer_id":44488063680673,"sku":"VET-005-60","price":149.14,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-5mg-pet-medicine-496.jpg?v=1778103585"},{"product_id":"dechra-vetoryl-capsules-for-dogs-10mg","title":"Vetoryl Capsules (Trilostane) for Dogs - 10mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 10 mg is an FDA-approved, prescription-only oral treatment for Cushing's disease in dogs. Each capsule holds 10 mg of trilostane, a synthetic steroid analogue that reduces cortisol production in the adrenal cortex. One capsule daily with food handles both pituitary-dependent and adrenal-dependent forms of the condition, making it a good fit for small dogs or those needing a step up from the 5 mg starting strength.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Suitable for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, the two forms of Cushing's disease most commonly diagnosed in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e Trilostane works by reversibly inhibiting 3-beta-hydroxysteroid dehydrogenase in the adrenal cortex, stopping excess cortisol from being produced at the source.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e In clinical field studies, most dogs showed reduced thirst, less urination, and lower panting within 14 days of beginning treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e A single oral dose each day is all it takes, slotting neatly into a daily routine for ongoing disease management.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrecise Dosing for Small Dogs:\u003c\/strong\u003e The 10 mg capsule gives veterinarians an accurate dosing step up for small dogs where the 5 mg strength falls short of what is therapeutically needed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Because trilostane's effect on cortisol production is reversible, your veterinarian can fine-tune or stop treatment safely as your dog's condition changes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 44.3473%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e10 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US Federal law limits this medication to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This medication is for oral use in dogs only and must never be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Your veterinarian determines the right starting dose for your dog based on body weight and overall health before writing the prescription.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e A single morning dose with food supports better absorption and helps keep stomach upset to a minimum.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the Capsule Whole:\u003c\/strong\u003e Do not open, empty, or split the capsule; give it exactly as dispensed every time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Check-In:\u003c\/strong\u003e Your vet will want to reassess your dog around the 10 to 14 day mark with an ACTH stimulation test and a full biochemistry panel.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e If test results or clinical signs call for a change, your veterinarian will guide any dose adjustment; never change the dose on your own.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch for Warning Signs:\u003c\/strong\u003e Vomiting, diarrhea, tiredness, poor appetite, weakness, or collapse are all reasons to stop the medication immediately and contact your vet.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Always wash your hands with soap and water after touching the capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Avoid use in any dog that has had an allergic reaction to trilostane in the past.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Dogs with existing liver or kidney problems should not use this medication; organ function should be confirmed before starting.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Animal studies have linked trilostane to birth defects and early pregnancy loss; never give to a pregnant dog under any circumstances.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Women who are pregnant or planning to conceive should not handle these capsules given the known risks trilostane poses to fetal development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression:\u003c\/strong\u003e Addison's disease can develop at any dose level; recovery can take months and some dogs do not fully regain normal adrenal function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Medications:\u003c\/strong\u003e Extra care is needed when a dog is already on heart treatment; share a full medication list with your vet before starting Vetoryl.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevious Mitotane Use:\u003c\/strong\u003e A minimum of one month must pass after stopping mitotane, and ACTH levels must normalize, before Vetoryl can safely begin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e This medication has not been assessed for safety in nursing females or males used for breeding; seek veterinary advice before use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e Poor appetite and vomiting are the most frequently reported reactions; stop the medication and contact your vet if they occur.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Reduced energy, lower activity levels, and physical weakness have been noted regularly in clinical and post-approval reports.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Some dogs develop loose stools; track bowel changes and let your veterinarian know if anything seems off.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Liver enzyme increases have been observed in some dogs; routine bloodwork is the most reliable way to spot this early.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Abnormal potassium or sodium levels can point to adrenal over-suppression and should be addressed with your vet promptly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e Severe reactions including kidney failure and Addison's disease have in some cases resulted in death; seek urgent veterinary care if your dog suddenly collapses or deteriorates.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at around 25°C (77°F), away from moisture and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication somewhere children and other animals simply cannot get to.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 10 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl 10 mg treats hyperadrenocorticism, commonly called Cushing's disease, in dogs. It covers both the pituitary-dependent form, which accounts for most cases, and the adrenal-dependent form, where a growth on the adrenal gland triggers excess cortisol production throughout the body.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the 10 mg capsule differ from the 5 mg capsule?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Both capsules contain trilostane and work the same way. The 10 mg capsule delivers double the dose in a single administration, making it the better choice for small dogs where the 5 mg strength does not quite reach a therapeutic level. Your vet will decide which strength is right based on your dog's weight.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 10 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Clinical studies found that most dogs showed visible improvement within 14 days of beginning Vetoryl. Reduced thirst, less frequent urination, and lower panting were among the first signs of progress. A follow-up ACTH stimulation test is typically scheduled at the 10 to 14 day point to assess how well the dose is working.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my dog need regular testing while on Vetoryl 10 mg?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Even at a low dose, Vetoryl can tip adrenal suppression too far and lead to Addison's disease. Routine ACTH stimulation tests and biochemistry panels help keep cortisol in a safe range and give your vet what they need to make informed dose adjustments along the way.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Vetoryl (Trilostane) 10 mg a cure for Cushing's disease in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl keeps the condition under control by reducing cortisol production, but the underlying disease does not go away. Once the medication stops, cortisol levels rise again and symptoms come back, which is why treatment is usually continued for the rest of the dog's life.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/855\" title=\"Fda - vetoryl drug approval\" aria-label=\"Visit a webpage about Fda - vetoryl drug approval\"\u003eFDA - Vetoryl Drug Approval\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.msdvetmanual.com\/endocrine-system\/the-pituitary-gland\/cushing-disease-pituitary-dependent-hyperadrenocorticism-in-animals\" title=\"Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\" aria-label=\"Visit a webpage about Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\"\u003eMerck Veterinary Manual – Cushing's Syndrome in Dogs\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.petmd.com\/pet-medication\/vetoryl\" title=\"Vetoryl® (trilostane) | medication: petmd | petmd\" aria-label=\"Visit a webpage about Vetoryl® (trilostane) | medication: petmd | petmd\"\u003ePetMD – Trilostane for Dogs\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44488078491809,"sku":"VET-010","price":104.44,"currency_code":"USD","in_stock":true},{"title":"60 Capsules","offer_id":44488078524577,"sku":"VET-010-60","price":208.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-10mg-pet-medicine-910.jpg?v=1778103596"},{"product_id":"dechra-vetoryl-capsules-for-dogs-30mg","title":"Vetoryl Capsules (Trilostane) for Dogs - 30mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 30 mg is an FDA-approved, prescription-only oral treatment for Cushing's disease in dogs. Each capsule holds 30 mg of trilostane, a synthetic steroid analogue that dials back cortisol production in the adrenal cortex. One capsule a day with food manages both pituitary-dependent and adrenal-dependent forms of the disease, making it a practical choice for medium-sized dogs needing a moderate therapeutic dose.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Works for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, covering the two most common forms seen in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e Trilostane reversibly blocks 3-beta-hydroxysteroid dehydrogenase in the adrenal cortex, cutting off the source of excess cortisol production.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e Field studies showed most dogs experienced less thirst, less urination, and reduced panting within just 14 days of starting therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e One oral dose a day fits easily into any routine, making long-term disease management much more manageable for pet owners.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMid-Range Strength Option:\u003c\/strong\u003e At 30 mg per capsule, this is a commonly prescribed mid-range choice that suits medium-sized dogs needing moderate trilostane levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Trilostane's effect on cortisol production can be reversed, giving your veterinarian the flexibility to adjust or stop treatment when needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 41.8539%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e30 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US Federal law limits this medication to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This medication is for oral use in dogs only and must never be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Your veterinarian determines the correct starting dose for your dog individually, taking body weight and health status into account before prescribing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e One dose each morning with food helps the body absorb it better and lowers the chance of stomach upset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the Capsule Whole:\u003c\/strong\u003e Never open, empty, or split a capsule; always give it exactly as dispensed without any modification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Check-In:\u003c\/strong\u003e Around 10 to 14 days after starting, your vet will want to see your dog again for an ACTH stimulation test and a full biochemistry check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e Any changes to the dose will be guided by test results and how your dog is responding clinically; always follow your veterinarian's lead on this.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch for Warning Signs:\u003c\/strong\u003e If your dog shows vomiting, diarrhea, unusual tiredness, loss of appetite, weakness, or collapse, stop the medication and call your vet straight away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Give your hands a good wash with soap and water after every time you handle the capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Do not give to any dog that has previously shown an allergic reaction to trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Not suitable for dogs with pre-existing liver or kidney conditions; both need to be checked before treatment begins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Trilostane has been linked to birth defects and early pregnancy loss in animal studies; never use in a pregnant dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Pregnant women or those trying to conceive should avoid handling these capsules entirely due to the risk trilostane poses to fetal development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression:\u003c\/strong\u003e Too much adrenal suppression can develop at any dose, leading to Addison's disease; some dogs take months to recover and a few never fully do.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Medications:\u003c\/strong\u003e Use carefully alongside heart disease treatments; let your vet know about every medication your dog is currently taking before starting this one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevious Mitotane Use:\u003c\/strong\u003e If your dog was previously on mitotane, at least one month must pass and ACTH levels must return to normal before switching to Vetoryl.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e Safety in nursing females and males intended for breeding has not been studied; check with your vet before use in these animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e Reduced appetite and vomiting are among the most common reactions; stop treatment and reach out to your vet if either persists.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Low energy, reduced activity, and physical weakness have come up regularly in both clinical studies and real-world use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose stools have been reported in some dogs; keep an eye on bowel habits and flag any changes to your veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Liver enzyme rises have been noted in some dogs; regular bloodwork is the best way to catch this early.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Shifts in potassium and sodium levels have been seen and can be a sign of adrenal over-suppression that needs prompt attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e In rare cases, severe reactions including kidney failure and Addison's disease have led to death; get your dog to a vet immediately if sudden collapse or rapid deterioration occurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at around 25°C (77°F), away from moisture and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication somewhere children and other animals simply cannot get to.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 30 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl 30 mg treats hyperadrenocorticism, better known as Cushing's disease, in dogs. It works for both the pituitary-dependent form, which is the most common, and the adrenal-dependent form, where a tumor on the adrenal gland drives excess cortisol production throughout the body.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the 30 mg capsule differ from the 10 mg capsule?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The 30 mg capsule delivers three times the dose of the 10 mg option in a single administration. It is better suited for medium-sized dogs where a lower strength would not reach a therapeutic level. Your veterinarian will decide which capsule strength best matches your dog's weight and clinical needs.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 30 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Most dogs showed noticeable improvement within 14 days of starting treatment in clinical field studies. Early signs of progress included less thirst, reduced urination, and lower panting levels. A follow-up ACTH stimulation test is usually scheduled around the 10 to 14 day mark to check how well the dose is working.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my dog need regular testing while on Vetoryl 30 mg?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Testing is essential because even at the right dose, Vetoryl can push adrenal suppression too far, leading to Addison's disease. Regular ACTH stimulation tests and biochemistry panels keep cortisol levels within a safe range and give your vet the information needed to fine-tune the dose over time.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Vetoryl (Trilostane) 30 mg a cure for Cushing's disease in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl manages the condition rather than curing it. It reduces cortisol production and relieves symptoms, but the underlying disease remains. Stopping the medication allows cortisol levels to climb again and symptoms to return, which is why most dogs stay on it for life.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\" title=\"Https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\" aria-label=\"Visit a webpage about Https:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\"\u003ehttps:\/\/www.aaha.org\/newstat\/publications\/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5855282\/\" title=\"Update on the use of trilostane in dogs - pmc\" aria-label=\"Visit a webpage about Update on the use of trilostane in dogs - pmc\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5855282\/\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44488071053473,"sku":"VET-030","price":128.14,"currency_code":"USD","in_stock":true},{"title":"60 Capsules","offer_id":44488071086241,"sku":"VET-030-60","price":256.28,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-30mg-pet-medicine-431.webp?v=1777636665"},{"product_id":"dechra-vetoryl-capsules-for-dogs-60mg","title":"Vetoryl Capsules (Trilostane) for Dogs, 60mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 60 mg is an FDA-approved, prescription-only oral treatment for Cushing's disease in dogs. Each capsule holds 60 mg of trilostane, a synthetic steroid analogue that dials back cortisol production in the adrenal cortex. One capsule a day with food manages both pituitary-dependent and adrenal-dependent forms of the disease, making it a strong fit for medium to large dogs needing a higher therapeutic dose.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Works for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, covering the two most common forms seen in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e Trilostane reversibly blocks 3-beta-hydroxysteroid dehydrogenase in the adrenal cortex, cutting off the source of excess cortisol production.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e Field studies showed most dogs experienced less thirst, less urination, and reduced panting within just 14 days of starting therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e One oral dose a day fits easily into any routine, making long-term disease management much more manageable for pet owners.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher-Strength Option:\u003c\/strong\u003e At 60 mg per capsule, this strength suits medium to large dogs that need more trilostane to bring cortisol levels under proper control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Trilostane's effect on cortisol production can be reversed, giving your veterinarian the flexibility to adjust or stop treatment when needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 44.5254%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e60 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US Federal law limits this medication to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This medication is for oral use in dogs only and must never be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Your veterinarian determines the correct starting dose for your dog individually, taking body weight and health status into account before prescribing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e One dose each morning with food helps the body absorb it better and lowers the chance of stomach upset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the Capsule Whole:\u003c\/strong\u003e Never open, empty, or split a capsule; always give it exactly as dispensed without any modification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Check-In:\u003c\/strong\u003e Around 10 to 14 days after starting, your vet will want to see your dog again for an ACTH stimulation test and a full biochemistry check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e Any changes to the dose will be guided by test results and how your dog is responding clinically; always follow your veterinarian's lead on this.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch for Warning Signs:\u003c\/strong\u003e If your dog shows vomiting, diarrhea, unusual tiredness, loss of appetite, weakness, or collapse, stop the medication and call your vet straight away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Give your hands a good wash with soap and water after every time you handle the capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Do not give to any dog that has previously shown an allergic reaction to trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Not suitable for dogs with pre-existing liver or kidney conditions; both need to be checked before treatment begins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Trilostane has been linked to birth defects and early pregnancy loss in animal studies; never use in a pregnant dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Pregnant women or those trying to conceive should avoid handling these capsules entirely due to the risk trilostane poses to fetal development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression:\u003c\/strong\u003e Too much adrenal suppression can develop at any dose, leading to Addison's disease; some dogs take months to recover and a few never fully do.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Medications:\u003c\/strong\u003e Use carefully alongside heart disease treatments; let your vet know about every medication your dog is currently taking before starting this one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevious Mitotane Use:\u003c\/strong\u003e If your dog was previously on mitotane, at least one month must pass and ACTH levels must return to normal before switching to Vetoryl.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e Safety in nursing females and males intended for breeding has not been studied; check with your vet before use in these animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e Reduced appetite and vomiting are among the most common reactions; stop treatment and reach out to your vet if either persists.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Low energy, reduced activity, and physical weakness have come up regularly in both clinical studies and real-world use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose stools have been reported in some dogs; keep an eye on bowel habits and flag any changes to your veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Liver enzyme rises have been noted in some dogs; regular bloodwork is the best way to catch this early.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Shifts in potassium and sodium levels have been seen and can be a sign of adrenal over-suppression that needs prompt attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e In rare cases, severe reactions including kidney failure and Addison's disease have led to death; get your dog to a vet immediately if sudden collapse or rapid deterioration occurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at around 25°C (77°F), away from moisture and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication somewhere children and other animals simply cannot get to.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 60 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl 60 mg treats hyperadrenocorticism, better known as Cushing's disease, in dogs. It works for both the pituitary-dependent form, which is the most common, and the adrenal-dependent form, where a tumor on the adrenal gland drives excess cortisol production throughout the body.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the 60 mg capsule differ from the 30 mg capsule?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The 60 mg capsule delivers double the dose of the 30 mg option in a single administration. It is better suited to medium and large dogs where a lower strength would not reach a therapeutic level. Your veterinarian will decide which capsule strength best matches your dog's weight and clinical needs.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 60 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Most dogs showed noticeable improvement within 14 days of starting treatment in clinical field studies. Early signs of progress included less thirst, reduced urination, and lower panting levels. A follow-up ACTH stimulation test is usually scheduled around the 10 to 14 day mark to check how well the dose is working.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my dog need regular testing while on Vetoryl 60 mg?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Testing is essential because even at the right dose, Vetoryl can push adrenal suppression too far, leading to Addison's disease. Regular ACTH stimulation tests and biochemistry panels keep cortisol levels within a safe range and give your vet the information needed to fine-tune the dose over time.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Vetoryl (Trilostane) 60 mg a cure for Cushing's disease in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl manages the condition rather than curing it. It reduces cortisol production and relieves symptoms, but the underlying disease remains. Stopping the medication allows cortisol levels to climb again and symptoms to return, which is why most dogs stay on it for life.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/855\" title=\"Fda - vetoryl drug approval\" aria-label=\"Visit a webpage about Fda - vetoryl drug approval\"\u003eFDA - Vetoryl Drug Approval\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.msdvetmanual.com\/endocrine-system\/the-pituitary-gland\/cushing-disease-pituitary-dependent-hyperadrenocorticism-in-animals\" title=\"Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\" aria-label=\"Visit a webpage about Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\"\u003eMerck Veterinary Manual – Cushing's Syndrome in Dogs\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.petmd.com\/pet-medication\/vetoryl\" title=\"Vetoryl® (trilostane) | medication: petmd | petmd\" aria-label=\"Visit a webpage about Vetoryl® (trilostane) | medication: petmd | petmd\"\u003ePetMD – Trilostane for Dogs\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44488083013793,"sku":"VET-060","price":162.45,"currency_code":"USD","in_stock":true},{"title":"60 Capsules","offer_id":44488083046561,"sku":"VET-060-60","price":324.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-60mg-pet-medicine-409.jpg?v=1778103605"},{"product_id":"dechra-vetoryl-capsules-for-dogs-120mg","title":"Vetoryl Capsules (Trilostane) for Dogs , 120mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 120 mg is an FDA-approved, prescription-only oral treatment for Cushing's disease in dogs. Each capsule holds 120 mg of trilostane, the strongest dose in the Vetoryl range, a synthetic steroid analogue that dials back cortisol production in the adrenal cortex. One capsule a day with food manages both pituitary-dependent and adrenal-dependent forms of the disease, making it the go-to choice for larger dogs needing the highest therapeutic dose.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Works for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, covering the two most common forms seen in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e Trilostane reversibly blocks 3-beta-hydroxysteroid dehydrogenase in the adrenal cortex, cutting off the source of excess cortisol production.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e Field studies showed most dogs experienced less thirst, less urination, and reduced panting within just 14 days of starting therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e One oral dose a day fits easily into any routine, making long-term disease management much more manageable for pet owners.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHighest-Strength Option:\u003c\/strong\u003e At 120 mg per capsule, this is the strongest Vetoryl dose available, designed for large dogs that need maximum trilostane levels for effective cortisol control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Trilostane's effect on cortisol production can be reversed, giving your veterinarian the flexibility to adjust or stop treatment when needed.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 43.2787%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 36.361%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 63.1818%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 36.361%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 63.1818%; height: 19.6023px;\"\u003e120 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US Federal law limits this medication to use by or on the order of a licensed veterinarian only.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e This medication is for oral use in dogs only and must never be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStarting Dose:\u003c\/strong\u003e Your veterinarian will calculate the right starting dose based on your dog's weight and current condition, then prescribe accordingly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e One dose each morning with food helps the body absorb it better and lowers the chance of stomach upset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep the Capsule Whole:\u003c\/strong\u003e Never open, empty, or split a capsule; always give it exactly as dispensed without any modification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Check-In:\u003c\/strong\u003e Around 10 to 14 days after starting, your vet will want to see your dog again for an ACTH stimulation test and a full biochemistry check.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e Any changes to the dose will be guided by test results and how your dog is responding clinically; always follow your veterinarian's lead on this.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWatch for Warning Signs:\u003c\/strong\u003e If your dog shows vomiting, diarrhea, unusual tiredness, loss of appetite, weakness, or collapse, stop the medication and call your vet straight away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Give your hands a good wash with soap and water after every time you handle the capsules.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity:\u003c\/strong\u003e Do not give to any dog that has previously shown an allergic reaction to trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Not suitable for dogs with pre-existing liver or kidney conditions; both need to be checked before treatment begins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Trilostane has been linked to birth defects and early pregnancy loss in animal studies; never use in a pregnant dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Pregnant women or those trying to conceive should avoid handling these capsules entirely due to the risk trilostane poses to fetal development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression:\u003c\/strong\u003e Too much adrenal suppression can develop at any dose, leading to Addison's disease; some dogs take months to recover and a few never fully do.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeart Medications:\u003c\/strong\u003e Use carefully alongside heart disease treatments; let your vet know about every medication your dog is currently taking before starting this one.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevious Mitotane Use:\u003c\/strong\u003e If your dog was previously on mitotane, at least one month must pass and ACTH levels must return to normal before switching to Vetoryl.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e Safety in nursing females and males intended for breeding has not been studied; check with your vet before use in these animals.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e Reduced appetite and vomiting are among the most common reactions; stop treatment and reach out to your vet if either persists.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Low energy, reduced activity, and physical weakness have come up regularly in both clinical studies and real-world use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose stools have been reported in some dogs; keep an eye on bowel habits and flag any changes to your veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Liver enzyme rises have been noted in some dogs; regular bloodwork is the best way to catch this early.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Shifts in potassium and sodium levels have been seen and can be a sign of adrenal over-suppression that needs prompt attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e In rare cases, severe reactions including kidney failure and Addison's disease have led to death; get your dog to a vet immediately if sudden collapse or rapid deterioration occurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Keep at around 25°C (77°F), away from moisture and direct sunlight.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication somewhere children and other animals simply cannot get to.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 120 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl 120 mg treats hyperadrenocorticism, better known as Cushing's disease, in dogs. It works for both the pituitary-dependent form, which is the most common, and the adrenal-dependent form, where a tumor on the adrenal gland drives excess cortisol production throughout the body.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the 120 mg capsule differ from the 60 mg capsule?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The 120 mg capsule is the strongest in the Vetoryl range, delivering double the dose of the 60 mg capsule per administration. It is designed for larger dogs where a lower strength would fall short of the therapeutic target. Your veterinarian will determine which strength matches your dog's weight and clinical needs.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 120 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Most dogs showed noticeable improvement within 14 days of starting treatment in clinical field studies. Early signs of progress included less thirst, reduced urination, and lower panting levels. A follow-up ACTH stimulation test is usually scheduled around the 10 to 14 day mark to check how well the dose is working.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my large dog need regular testing while on Vetoryl 120 mg?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Testing is essential because even at the right dose, Vetoryl can push adrenal suppression too far, causing Addison's disease. Regular ACTH stimulation tests and biochemistry panels keep cortisol levels within the safe target range and give your vet the information needed to fine-tune the dose over time.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is Vetoryl (Trilostane) 120 mg a cure for Cushing's disease in large dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl manages the condition rather than curing it. It reduces cortisol production and relieves symptoms, but the underlying disease remains. Stopping the medication allows cortisol levels to climb again and symptoms to return, which is why most dogs stay on it for life.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/855\" title=\"Fda - vetoryl drug approval\" aria-label=\"Visit a webpage about Fda - vetoryl drug approval\"\u003eFDA - Vetoryl Drug Approval\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.msdvetmanual.com\/endocrine-system\/the-pituitary-gland\/cushing-disease-pituitary-dependent-hyperadrenocorticism-in-animals\" title=\"Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\" aria-label=\"Visit a webpage about Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\"\u003eMerck Veterinary Manual – Cushing's Syndrome in Dogs\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.petmd.com\/pet-medication\/vetoryl\" title=\"Vetoryl® (trilostane) | medication: petmd | petmd\" aria-label=\"Visit a webpage about Vetoryl® (trilostane) | medication: petmd | petmd\"\u003ePetMD – Trilostane for Dogs\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44488087470241,"sku":"VET-120","price":249.28,"currency_code":"USD","in_stock":true},{"title":"60 Capsules","offer_id":44488087503009,"sku":"VET-120-60","price":498.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-120mg-pet-medicine-482.jpg?v=1778103609"},{"product_id":"anipryl-tablets","title":"Anipryl (selegiline) Tablets, 30 tablets","description":"\u003cp align=\"center\"\u003e\u003cimg src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" data-files=\"rx-map.jpg\" loading=\"lazy\"\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eSupports Cognitive Function and PDH in Dogs\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eAnipryl is a prescription tablet for dogs that is given by mouth to help manage signs of canine cognitive dysfunction and uncomplicated pituitary dependent hyperadrenocorticism. It contains selegiline hydrochloride, which works by increasing dopamine levels in the brain to support normal brain function and behavior. Given once a day, it comes in flexible dose strengths and has been clinically shown to improve both cognitive symptoms and signs related to PDH.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCognitive Support:\u003c\/strong\u003e Helps control disorientation, altered sleep cycles, and loss of housetraining in aging dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDH Symptom Control:\u003c\/strong\u003e Assists in managing clinical signs of uncomplicated pituitary-dependent hyperadrenocorticism in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDopamine Enhancement:\u003c\/strong\u003e Selectively inhibits MAO B to increase dopamine levels in the central nervous system.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce Daily Dosing:\u003c\/strong\u003e Administered once daily, preferably in the morning, for convenient long-term management.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFlexible Strength Options:\u003c\/strong\u003e Available in multiple tablet strengths to allow individualized dosing based on body weight.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e10 mg Tablets\u003cbr\u003e15 mg Tablets\u003cbr\u003e30 mg Tablets\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eComposition Table\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 42.9225%; height: 208px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e2 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e5 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e10 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e15 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd width=\"201\" style=\"width: 66.4219%; height: 35.5966px;\"\u003e\n\u003cp\u003eSelegiline Hydrochloride\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"101\" style=\"width: 33.3009%; height: 35.5966px;\"\u003e\n\u003cp\u003e30 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 67.6786%; height: 163px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd width=\"175\" style=\"width: 30.9609%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eIndication\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"129\" style=\"width: 22.6806%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended Dosage\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"74\" style=\"width: 13.1404%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eFrequency\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"189\" style=\"width: 32.2209%; height: 55.1989px;\"\u003e\n\u003cp\u003e\u003cstrong\u003eNotes\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd width=\"175\" style=\"width: 30.9609%; height: 55.1989px;\"\u003e\n\u003cp\u003eCanine Cognitive Dysfunction Syndrome\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"129\" style=\"width: 22.6806%; height: 55.1989px;\"\u003e\n\u003cp\u003e0.5 to 1.0 mg per kg body weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"74\" style=\"width: 13.1404%; height: 55.1989px;\"\u003e\n\u003cp\u003eOnce daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"189\" style=\"width: 32.2209%; height: 55.1989px;\"\u003e\n\u003cp\u003ePreferably administered in the morning.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 94.4034px;\"\u003e\n\u003ctd width=\"175\" style=\"width: 30.9609%; height: 94.4034px;\"\u003e\n\u003cp\u003ePituitary Dependent Hyperadrenocorticism\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"129\" style=\"width: 22.6806%; height: 94.4034px;\"\u003e\n\u003cp\u003e1.0 mg per kg body weight\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"74\" style=\"width: 13.1404%; height: 94.4034px;\"\u003e\n\u003cp\u003eOnce daily\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"189\" style=\"width: 32.2209%; height: 94.4034px;\"\u003e\n\u003cp\u003eMay increase to maximum 2.0 mg per kg if no improvement after 2 months.\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e This medication is restricted to use by or on the order of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMorning Administration:\u003c\/strong\u003e Administer once daily, preferably in the morning, to support recommended therapeutic use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustment:\u003c\/strong\u003e Adjust dosage based on individual response and tolerance, under veterinary supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDH Reassessment:\u003c\/strong\u003e If no improvement after dose increase, reevaluate and consider alternative therapy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioral Use Limitation:\u003c\/strong\u003e Not recommended for the treatment of other behavior problems, such as aggression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interactions:\u003c\/strong\u003e Avoid concurrent use with SSRIs, tricyclic antidepressants, or other antidepressants.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFluoxetine Washout:\u003c\/strong\u003e Allow at least five weeks after discontinuing fluoxetine before starting Anipryl.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDH Confirmation:\u003c\/strong\u003e Confirm pituitary-dependent hyperadrenocorticism diagnosis before initiating therapy for that condition.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Safety:\u003c\/strong\u003e Safety has not been determined in breeding, pregnant, or lactating dogs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Signs:\u003c\/strong\u003e Vomiting and diarrhea were commonly reported during clinical field trials.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRestlessness Behavior:\u003c\/strong\u003e Hyperactivity, irritability, and restlessness were observed in treated dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAppetite Changes:\u003c\/strong\u003e Anorexia and weight loss have been reported in some dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurologic Effects:\u003c\/strong\u003e Ataxia, disorientation, incoordination, and seizure-like activity were reported.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy Weakness:\u003c\/strong\u003e Lethargy and generalized weakness occurred in some treated dogs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature:\u003c\/strong\u003e Store at controlled room temperature between 20° to 25° Celsius.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOriginal Packaging:\u003c\/strong\u003e Keep tablets in original blister packaging until administration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChild Safety:\u003c\/strong\u003e Keep out of reach of children and not for human use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is Anipryl used for in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Anipryl is prescribed to manage the symptoms linked to canine cognitive dysfunction and uncomplicated pituitary dependent hyperadrenocorticism. It increases dopamine activity in the brain, which can help reduce behavior changes and hormone related issues seen in affected dogs.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How long does Anipryl take to show results?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In clinical trials for cognitive dysfunction, improvement was observed after four weeks of treatment, with some dogs continuing to improve up to three months. For pituitary-dependent hyperadrenocorticism, many responding dogs showed improvement within one to two months of therapy initiation.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: What is the recommended dosage of Anipryl for dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e For canine cognitive dysfunction, the recommended dosage is 0.5 to 1.0 mg per kg once daily. For pituitary-dependent hyperadrenocorticism, the recommended dosage is 1.0 mg per kg once daily, which may be increased to 2.0 mg per kg if needed.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: Can Anipryl be given with other antidepressant medications?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Anipryl should not be used together with selective serotonin reuptake inhibitors, tricyclic antidepressants, or other antidepressant medications. After stopping Anipryl, wait at least 14 days before starting any of these drugs. If fluoxetine has been used, a longer waiting period of five weeks is required before beginning Anipryl.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: What are the common side effects of Anipryl in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e In clinical trials, the most commonly reported side effects included vomiting, diarrhea, increased activity, loss of appetite, tiredness, and nervous system changes such as unsteady movement or confusion. Most of these reactions were mild, but a small number of dogs needed a dose adjustment or had to stop the medication.\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"10-mg","offer_id":45026758754465,"sku":"10000282","price":117.99,"currency_code":"USD","in_stock":false},{"title":"15-mg","offer_id":45026755608737,"sku":"10000283","price":123.56,"currency_code":"USD","in_stock":true},{"title":"30-mg","offer_id":45026758787233,"sku":"10000284","price":125.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/anipryl-selegiline-tablets-30-pet-medication-162.png?v=1778134339"},{"product_id":"dechra-vetoryl-capsules-trilostane-for-dogs-20mg","title":"Vetoryl Capsules (Trilostane) for Dogs - 20mg","description":"\u003ch2\u003eOnce-Daily Trilostane Capsule for Cushing's Disease in Dogs\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eVetoryl Capsules (Trilostane) 20 mg is an FDA-approved, prescription-only oral medication for managing Cushing's disease in dogs. Each capsule delivers 20 mg of trilostane, a synthetic steroid analogue that reversibly inhibits cortisol production in the adrenal cortex. Given once daily with food, it effectively manages both pituitary-dependent and adrenal-dependent forms of the disease, offering a precise intermediate dose option for small to medium-sized dogs.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Cushing's Disease:\u003c\/strong\u003e Indicated for both pituitary-dependent and adrenal-dependent hyperadrenocorticism, the two most common forms in dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAddresses Root Cause:\u003c\/strong\u003e Trilostane blocks excessive cortisol by reversibly inhibiting 3-beta-hydroxysteroid dehydrogenase within the adrenal cortex of dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Proven Results:\u003c\/strong\u003e Field studies showed improvement in signs like reduced thirst, urination, and panting in most dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Convenience:\u003c\/strong\u003e Given orally once a day, making it straightforward to include in a dog's long-term daily routine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrecise Intermediate Dose:\u003c\/strong\u003e The 20 mg capsule bridges the gap between 10 mg and 30 mg strengths for more accurate dosing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReversible Suppression:\u003c\/strong\u003e Trilostane's cortisol inhibition is reversible, allowing therapy to be safely adjusted or stopped under veterinary guidance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 36.1546%; height: 5px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 37.9811%; height: 19.6023px;\"\u003eTrilostane\u003c\/td\u003e\n\u003ctd style=\"width: 61.7418%; height: 19.6023px;\"\u003e20 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eOther Ingredients\u003c\/h4\u003e\n\u003cp\u003eGelatin capsule shell, Lactose, Magnesium Stearate, Colloidal Silicon Dioxide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e US law requires this drug to be given only when prescribed or directed by a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFor Dogs Only:\u003c\/strong\u003e Intended for oral use in dogs only and must not be given to humans or other animal species.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGive With Food:\u003c\/strong\u003e Administer orally once daily, preferably in the morning with food to improve absorption and reduce stomach upset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Divide Capsules:\u003c\/strong\u003e Never empty the capsule contents or split it; always administer the whole capsule as dispensed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonitor After Starting:\u003c\/strong\u003e Around 10 to 14 days in, a re-examination, ACTH stimulation test, and serum biochemical panel should be conducted.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e Any changes to the dose should be based on ACTH stimulation results and made under your veterinarian's guidance.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStop If Side Effects Occur:\u003c\/strong\u003e Stop therapy immediately and contact your veterinarian if vomiting, diarrhea, lethargy, appetite loss, or collapse occurs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Always wash hands thoroughly with soap and water after handling the capsules each time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHypersensitivity Contraindication:\u003c\/strong\u003e Do not use in dogs that have previously shown an allergic reaction or hypersensitivity to trilostane.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver or Kidney Disease:\u003c\/strong\u003e Dogs with hepatic disease or poor kidney function should not receive Vetoryl, and organ tests should be done first.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant Dogs:\u003c\/strong\u003e Trilostane has caused teratogenic effects and early pregnancy loss in lab animals; never use in pregnant dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePregnant Handlers:\u003c\/strong\u003e Women who are pregnant or trying to conceive must never handle Vetoryl capsules due to teratogenic risks.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdrenal Over-Suppression Risk:\u003c\/strong\u003e Addison's disease can develop at any dose and some dogs may never fully regain normal adrenal function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution With Heart Medications:\u003c\/strong\u003e Use with caution in dogs on heart disease medications; inform your veterinarian of all current medications beforehand.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrior Mitotane Treatment:\u003c\/strong\u003e Wait at least one month after stopping mitotane and until ACTH levels normalize before starting Vetoryl therapy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactating and Breeding Males:\u003c\/strong\u003e The safety of Vetoryl has not been evaluated in lactating dogs or males intended for breeding.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnorexia and Vomiting:\u003c\/strong\u003e Loss of appetite and vomiting are among the most commonly reported side effects; contact your vet immediately.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLethargy and Weakness:\u003c\/strong\u003e Depression, reduced activity, and physical weakness have been frequently reported in both field studies and post-approval experience.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose stools or diarrhea have been reported; monitor your dog's bowel movements and report any changes promptly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes:\u003c\/strong\u003e Elevated hepatic enzyme levels have been reported; routine biochemical monitoring helps detect these changes at an early stage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Elevated potassium and decreased sodium levels have been reported and may signal adrenal over-suppression in treated dogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerious Adverse Events:\u003c\/strong\u003e Death has been reported in some cases; contact your veterinarian immediately if sudden collapse or rapid deterioration occurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store at room temperature 25°C (77°F), with excursions permitted between 15°C and 30°C (59°F to 86°F).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store this prescription medication securely out of reach of children and other animals at all times.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ro\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ro\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What condition does Vetoryl (Trilostane) 20 mg treat in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Vetoryl Capsules treat hyperadrenocorticism, commonly known as Cushing's disease, in dogs. It works for both pituitary-dependent and adrenal-dependent forms of the disease, where excess cortisol is produced by either a pituitary or adrenal gland tumor, causing various clinical signs.\u003c\/p\u003e\n\u003ch3\u003eQ2: How is the 20 mg capsule different from other Vetoryl strengths?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The 20 mg trilostane capsule provides an intermediate option between the 10 mg and 30 mg strengths. It allows veterinarians to prescribe a more accurate weight-based dose for dogs whose ideal dose falls between those two strengths, avoiding unnecessary over or under-dosing.\u003c\/p\u003e\n\u003ch3\u003eQ3: How quickly does Vetoryl 20 mg start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Clinical field studies showed improvement in most dogs within 14 days of starting Vetoryl. Early signs include reduced thirst, less urination, decreased panting, and better appetite. A follow-up ACTH stimulation test is conducted after the first 10 to 14 days.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why does my dog need regular testing while on Vetoryl?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Regular ACTH stimulation tests and biochemical panels are required because Vetoryl can cause adrenal over-suppression at any dose, leading to Addison's disease. Monitoring keeps cortisol within a safe range and allows your veterinarian to adjust the dose appropriately and safely over time.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is the Cushing's disease trilostane capsule a permanent cure for dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e No. Vetoryl controls the signs of Cushing's disease by suppressing excess cortisol but does not cure the underlying condition. If the medication is stopped or missed regularly, cortisol levels will rise again and signs will return, making lifelong therapy typically necessary for dogs.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/855\" title=\"Fda - vetoryl drug approval\" aria-label=\"Visit a webpage about Fda - vetoryl drug approval\"\u003eFDA - Vetoryl Drug Approval\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.msdvetmanual.com\/endocrine-system\/the-pituitary-gland\/cushing-disease-pituitary-dependent-hyperadrenocorticism-in-animals\" title=\"Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\" aria-label=\"Visit a webpage about Cushing disease (pituitary-dependent hyperadrenocorticism) in animals - endocrine system - msd veterinary manual\"\u003eMerck Veterinary Manual – Cushing's Syndrome in Dogs\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.petmd.com\/pet-medication\/vetoryl\" title=\"Vetoryl® (trilostane) | medication: petmd | petmd\" aria-label=\"Visit a webpage about Vetoryl® (trilostane) | medication: petmd | petmd\"\u003ePetMD – Trilostane for Dogs\u003c\/a\u003e\u003c\/p\u003e","brand":"Dechra","offers":[{"title":"30 Capsules","offer_id":44670645338273,"sku":"VET-020","price":119.06,"currency_code":"USD","in_stock":true},{"title":"60 Capsules","offer_id":44670645371041,"sku":"VET-020-60","price":238.12,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/vetoryl-capsules-trilostane-for-dogs-20mg-pet-medicine-262.webp?v=1777974407"}],"url":"https:\/\/hordypaw.shop\/en-ro\/collections\/cushings-disease.oembed","provider":"HardyPaw","version":"1.0","type":"link"}