{"product_id":"zonisamide-capsules-100mg","title":"Zonisamide Capsules, 100mg","description":"\u003cp align=\"center\"\u003e\u003cimg loading=\"lazy\" data-files=\"rx-map.jpg\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\"\u003e\u003c\/p\u003e\n\u003ch2\u003eAnticonvulsant for Seizure Management in Dogs and Cats\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eZonisamide 100mg is a prescription anticonvulsant used off-label in dogs and cats to manage epilepsy and reduce both the frequency and severity of seizures. It can work as a standalone first-line therapy or alongside other seizure medications when control is difficult to achieve. While FDA-approved for human use, its off-label use in pets is widely accepted and considered a standard of care in veterinary neurology practice.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eControls Seizure Disorders:\u003c\/strong\u003e Reduces seizure frequency and severity in dogs and cats, whether used on its own or combined with other anticonvulsant medications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad-Spectrum Anticonvulsant:\u003c\/strong\u003e Effective against both primary generalised and partial-onset epilepsies in dogs, covering a wide range of seizure types.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWorks as Sole or Add-On Therapy:\u003c\/strong\u003e Suitable as the only seizure medication for many dogs, and equally effective as an added treatment when phenobarbital alone is not enough.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnce-Daily Dosing in Cats:\u003c\/strong\u003e Thanks to its longer half-life in cats, zonisamide only needs to be given once a day, making it easier for owners to stay consistent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRelatively Fast Acting:\u003c\/strong\u003e Most pets begin responding to zonisamide within 1 to 2 days of starting treatment, offering fairly quick anticonvulsant activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-Addictive for Long-Term Use:\u003c\/strong\u003e Zonisamide carries no dependency risk, making it a practical long-term choice for pets needing ongoing seizure management.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eZonisamide\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eZonisamide is a prescription-only medication. A valid prescription from a licensed veterinarian is required to purchase this medicine.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for dosage, frequency, and duration of treatment for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eGiving capsules to pets can feel tricky at first, but a pill pocket or pill wrap takes most of the stress out of it. Tuck the capsule inside and let your pet take it as a treat.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en-hk\/collections\/dog-pill-pockets\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/en-hk\/collections\/cat-pill-pockets\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pets with Liver Disease:\u003c\/strong\u003e Zonisamide must be avoided in pets with existing liver disease, as it can worsen liver function and has been linked to rare serious liver damage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Pregnant or Breeding Animals:\u003c\/strong\u003e Studies show zonisamide causes serious heart defects in puppies born to mothers given this drug during pregnancy; avoid use in pregnant or breeding animals entirely.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution with Sulfonamide Allergy:\u003c\/strong\u003e Pets with a known sensitivity to sulfonamide-based medications may face a higher risk of an allergic reaction, as zonisamide belongs to this drug class.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interaction with Phenobarbital:\u003c\/strong\u003e Phenobarbital speeds up zonisamide clearance from the body, which may affect dosing; this interaction can continue for up to 10 weeks after phenobarbital is stopped.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Nursing Animals:\u003c\/strong\u003e Whether zonisamide passes into maternal milk is not yet known; nursing animals should only receive this medication under direct and close veterinary supervision.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegular Monitoring Required:\u003c\/strong\u003e Annual blood work including a full blood count, chemistry panel, and urinalysis is recommended, along with at least two vet visits per year on this medication.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSedation and Incoordination (Dogs):\u003c\/strong\u003e The most common effects in dogs are low energy, drowsiness, and unsteady walking; let your vet know if these are severe or not settling down.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReduced Appetite and Vomiting (Dogs):\u003c\/strong\u003e Some dogs experience decreased appetite or vomiting on this medication; giving it with food often helps reduce these stomach-related effects.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGI Signs in Cats:\u003c\/strong\u003e Cats may show reduced appetite, loose stools, vomiting, incoordination, or sleepiness; these effects can linger for 1 to 2 days after stopping due to the drug's longer half-life in cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRare Liver Damage:\u003c\/strong\u003e Serious liver disease affects less than 1% of treated dogs; watch for complete loss of appetite, extreme lethargy, or yellowing of the skin, gums, or eyes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrinary Stones and Kidney Changes:\u003c\/strong\u003e Zonisamide can shift urine pH in ways that encourage stone formation; severe kidney disease has also been reported in some dogs on this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioural or Skin Changes:\u003c\/strong\u003e Aggression and skin reactions can occasionally occur in pets on this medication; report any unusual changes in behaviour or skin to your vet promptly.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eStore at Room Temperature:\u003c\/strong\u003e Keep zonisamide capsules at a stable room temperature, away from excessive heat to preserve their quality and effectiveness.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect from Light and Moisture:\u003c\/strong\u003e Store in a dry place away from direct light exposure to maintain the stability and potency of the capsules over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Away from Children and Pets:\u003c\/strong\u003e Store in a secure, locked location that children and other animals in the household cannot access to prevent accidental ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNote: \u003c\/strong\u003e\u003c\/span\u003eFor generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-hk\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-hk\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What is zonisamide 100mg used for in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Zonisamide is an off-label anticonvulsant prescribed in dogs and cats to manage epilepsy and bring seizure frequency and severity under control. It works well on its own for many pets and can also be added to existing seizure treatment plans when adequate control has not been achieved.\u003c\/p\u003e\n\u003ch3\u003eQ2: Can zonisamide for seizures be stopped suddenly in pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Stopping zonisamide abruptly is not safe, as it can trigger rebound seizures in pets. Any reduction or discontinuation of this medication should always be done gradually and only under your veterinarian's direct guidance. Never adjust the dose on your own without consulting your vet first.\u003c\/p\u003e\n\u003ch3\u003eQ3: What are the warning signs of liver problems in pets on zonisamide?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Watch for a complete loss of appetite, sudden and severe lethargy, or a yellow tint developing in your pet's skin, gums, or eyes. These signs can point to serious liver damage, which is a rare but potentially life-threatening side effect seen in less than 1% of treated dogs.\u003c\/p\u003e\n\u003ch3\u003eQ4: Does phenobarbital interact with zonisamide in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Phenobarbital causes zonisamide to clear from the body faster, which can affect how well seizures are controlled and may require dose adjustments. This interaction does not stop right away when phenobarbital is discontinued and can carry on for as long as 10 weeks afterward.\u003c\/p\u003e\n\u003ch3\u003eQ5: Is zonisamide safe for pregnant or nursing dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Zonisamide must not be given to pregnant animals, as research has shown it causes serious heart defects in offspring born to mothers who received this drug during pregnancy. Use in nursing animals is only considered when a vet determines the benefit clearly outweighs any potential risk involved.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020789s034lbl.pdf\" title=\"Https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020789s034lbl.pdf\" aria-label=\"Visit a webpage about Https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020789s034lbl.pdf\"\u003ehttps:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020789s034lbl.pdf\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.medicines.org.uk\/emc\/product\/10068\/smpc\" title=\"Zonisamide 100mg hard capsules - summary of product characteristics (smpc) - (emc) | 10068\" aria-label=\"Visit a webpage about Zonisamide 100mg hard capsules - summary of product characteristics (smpc) - (emc) | 10068\"\u003ehttps:\/\/www.medicines.org.uk\/emc\/product\/10068\/smpc\u003c\/a\u003e\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 capsule","offer_id":41776749510817,"sku":"203284-1","price":3.0,"currency_code":"HKD","in_stock":true},{"title":"30 capsules","offer_id":44422669336737,"sku":"203284-30","price":88.0,"currency_code":"HKD","in_stock":true},{"title":"60 capsules","offer_id":44422669369505,"sku":"203284-60","price":176.0,"currency_code":"HKD","in_stock":true},{"title":"100 capsules","offer_id":41776749478049,"sku":"203284","price":279.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/zonisamide-capsules-100mg-pet-medicine-274.png?v=1778112606","url":"https:\/\/hordypaw.shop\/en-hk\/products\/zonisamide-capsules-100mg","provider":"HardyPaw","version":"1.0","type":"link"}