{"product_id":"cerenia-maropitant-citrate-injectable-solution-20-ml","title":"Cerenia (Maropitant Citrate) Injectable Solution 10mg\/mL (20 mL)","description":"\u003ch2\u003eFDA-Approved NK1 Antiemetic Injectable Solution for Dogs and Cats\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eCerenia (Maropitant Citrate) Injectable Solution 10 mg\/mL is an FDA-approved prescription antiemetic for subcutaneous or intravenous use in dogs and cats, supplied in 20 mL amber glass vials. Maropitant is an NK1 receptor antagonist that blocks substance P, the neurotransmitter that triggers vomiting, in the central nervous system. It prevents and treats acute vomiting in dogs and treats vomiting in cats.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAntiemetic Action:\u003c\/strong\u003e Blocks substance P at NK1 receptors in the brain, stopping both central and peripheral vomiting causes.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHigh Bioavailability:\u003c\/strong\u003e Reaches 91% bioavailability in dogs and 91.3% in cats after subcutaneous injection with each dose.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eProven in Dogs:\u003c\/strong\u003e In a US field study, only 21.4% of Cerenia-treated dogs vomited versus 50% in the placebo group.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eProven in Cats:\u003c\/strong\u003e Only 1.8% of treated cats vomited in the 24 hours after treatment compared to 18.5% of placebo cats.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eChemo Vomiting Prevention:\u003c\/strong\u003e In a chemotherapy study, 94.9% of Cerenia-treated dogs did not vomit versus just 4.9% of placebo dogs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eReduces Injection Discomfort:\u003c\/strong\u003e Using the chilled product for subcutaneous injections can lower the pain response at the injection site.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eMaropitant (as Maropitant Citrate): 10 mg per mL\u003c\/p\u003e\n\u003ch4\u003eInactive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSulphobutylether-beta-cyclodextrin 63 mg\/mL, meta-cresol 3.3 mg\/mL, water for injection\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDirections for Use\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Cerenia Injectable Solution is federally restricted and must only be given under a licensed veterinarian's direct order.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eYoung Dogs SC Only:\u003c\/strong\u003e Give SC at 1 mg\/kg (0.1 mL\/kg) once daily for up to 5 days; IV not cleared at this age.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDogs SC or IV:\u003c\/strong\u003e Give SC or IV at 1 mg\/kg once daily over 1 to 2 minutes, up to 5 days.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCats SC or IV:\u003c\/strong\u003e Give SC or IV at 1 mg\/kg once daily over 1 to 2 minutes, up to 5 days.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePre-Chemotherapy Dosing:\u003c\/strong\u003e Give IV or SC at 1 mg\/kg once, 45 to 60 minutes before chemotherapy or emetogenic treatment begins.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eUse Chilled Product:\u003c\/strong\u003e Always use refrigerated solution for SC injections, as the cooler temperature helps reduce discomfort at the site.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTransition to Tablets:\u003c\/strong\u003e Once vomiting settles, Cerenia Tablets at 2 mg\/kg daily can maintain prevention in dogs as the vet directs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eFind Underlying Cause:\u003c\/strong\u003e Always work to identify the root cause of vomiting; reassess the case if vomiting continues despite ongoing treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eGI Obstruction Caution:\u003c\/strong\u003e Do not use in pets that may have swallowed toxins or have a gut blockage without a full vet evaluation first.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLiver Disease Caution:\u003c\/strong\u003e Pets with poor liver function break down this drug differently and will need careful watching throughout the full treatment course.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHighly Protein Bound:\u003c\/strong\u003e This drug competes for protein binding in the blood, so use carefully alongside NSAIDs, heart medications, or seizure drugs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBreeding Animal Caution:\u003c\/strong\u003e This product has not been tested in pregnant, nursing, or breeding animals; check with your vet before giving it to any of these pets.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eYoung Puppy Caution:\u003c\/strong\u003e Puppies younger than 11 weeks showed bone marrow changes in studies; no such changes were seen in those 16 weeks and older.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eHuman Handling Precautions:\u003c\/strong\u003e Keep away from skin and eyes; if eye contact happens, rinse thoroughly with water for a full 15 minutes and get medical help.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cp\u003eIn Dogs:\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eInjection Site Pain:\u003c\/strong\u003e Discomfort or vocalization at the injection site is common; chilled product for SC use may help reduce this.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDepression and Lethargy:\u003c\/strong\u003e Tiredness and low mood have been reported in post-approval data and field study results for dogs receiving Cerenia.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAnorexia and Hypersalivation:\u003c\/strong\u003e Reduced appetite and excessive drooling have been noted; contact your vet if either issue does not ease up.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSerious Reactions:\u003c\/strong\u003e Facial swelling, seizures, fever, and breathing trouble have been reported; get emergency veterinary care right away.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIn Cats:\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eInjection Discomfort:\u003c\/strong\u003e During field studies, a number of cats resisted injection by backing away or vocalizing; keeping the solution cold before use may help.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDepression and Anorexia:\u003c\/strong\u003e Tiredness, poor appetite, and drooling are the side effects cats most commonly show; keep a close eye on your cat after dosing.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNeurological Signs:\u003c\/strong\u003e Some cats have shown shaking, loss of balance, seizures, or breathing difficulty after use; reach out to your vet if this happens.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRefrigerated Storage:\u003c\/strong\u003e Keep refrigerated to maintain stability and preserve the formulation's binding properties, which break down once warmed.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Store the 20 mL amber vial away from children and all pets to prevent accidental contact or ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-hk\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-hk\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What is Cerenia Injectable Solution used for in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cerenia Injectable Solution 10 mg\/mL prevents and treats acute vomiting in dogs, including vomiting brought on by chemotherapy. In cats, it is used to treat vomiting. It can be given by subcutaneous injection or through an IV line, depending on the age and species of the patient.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: How does Cerenia maropitant injection stop vomiting in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Maropitant works by blocking NK1 receptors in the brain's vomiting center, shutting down the substance P pathway that sets off the vomiting reflex. This stops both central and peripheral vomiting triggers, including those caused by apomorphine, cisplatin, and other emetogenic drugs.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: What is the correct Cerenia injectable dose for dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Dogs and cats 4 months and older receive 1 mg\/kg (0.1 mL\/kg) once daily for up to 5 days by SC or IV over 1 to 2 minutes. For dogs between 2 and 4 months old, the same dose applies but only the subcutaneous route is cleared for this younger age group.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: Can Cerenia Injectable Solution interact with other medications in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. Maropitant is highly protein bound (99.5% in dogs, 99.1% in cats), which means it may interact with other protein-bound drugs including NSAIDs, cardiac medications, anticonvulsants, and behavioral drugs. Always inform your veterinarian of all current medications before administering Cerenia to avoid potential interactions.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: Why should Cerenia maropitant citrate injection be stored in the refrigerator?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cold storage keeps the binding between sulphobutylether-beta-cyclodextrin and maropitant intact, which is key to the product's stability. Using the chilled solution for SC injections also lowers discomfort at the injection site, as this binding breaks down quickly once the vial reaches room temperature.\u003c\/p\u003e\n\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\u003ca href=\"https:\/\/www.msdvetmanual.com\/multimedia\/table\/antiemetic-drugs\" title=\"Table: antiemetic drugs-msd veterinary manual\" aria-label=\"Visit a webpage about Table: antiemetic drugs-msd veterinary manual\"\u003ehttps:\/\/www.msdvetmanual.com\/multimedia\/table\/antiemetic-drugs\u003c\/a\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003ca href=\"https:\/\/vcahospitals.com\/know-your-pet\/vomiting-in-dogs\" title=\"Https:\/\/vcahospitals.com\/know-your-pet\/vomiting-in-dogs\" aria-label=\"Visit a webpage about Https:\/\/vcahospitals.com\/know-your-pet\/vomiting-in-dogs\"\u003ehttps:\/\/vcahospitals.com\/know-your-pet\/vomiting-in-dogs\u003c\/a\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003ca href=\"https:\/\/www.petmd.com\/pet-medication\/cerenia-maropitant-for-dogs\" title=\"Maropitant (cerenia) for dogs | dog, pet medication: petmd | petmd\" aria-label=\"Visit a webpage about Maropitant (cerenia) for dogs | dog, pet medication: petmd | petmd\"\u003ehttps:\/\/www.petmd.com\/pet-medication\/cerenia-maropitant-for-dogs\u003c\/a\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/818\" title=\"Https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadfoi\/818\" aria-label=\"Visit a webpage about Https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadfoi\/818\"\u003ehttps:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/818\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Zoetis","offers":[{"title":"Default Title","offer_id":43596913639585,"sku":"540744","price":79615.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/cerenia-maropitant-citrate-injectable-solution-10mg-ml-20-ml-pet-822.jpg?v=1778539654","url":"https:\/\/hordypaw.shop\/en-hk\/products\/cerenia-maropitant-citrate-injectable-solution-20-ml","provider":"HardyPaw","version":"1.0","type":"link"}