Heart & Liver Supplements for Dogs

Sort + Filter
Show
denamarin chewable tablets chewable denamarin for dogs

Nutramax Denamarin Liver Health Supplement for Dogs of All Sizes, With S-Adenosylmethionine (SAMe) and Silybin

Nutramax

(6)
From
$359.00
$287.20 Save 20% on 1st Autoship, 5% off future orders
denamarin for dogs denamarin liver health supplement

Nutramax Denamarin Liver Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe) and Silybin

Nutramax

(3)
From
$605.00
$484.00 Save 20% on 1st Autoship, 5% off future orders
Nutramax Denosyl Liver and Brain Health Supplement for Large Dogs With S-Adenosylmethionine (SAMe) - 1 pack (30 Nutramax Denosyl Liver and Brain Health Supplement for Large Dogs With S-Adenosylmethionine (SAMe) - Dog Supplements &

Nutramax Denosyl Liver and Brain Health Supplement for Large Dogs, With S-Adenosylmethionine (SAMe)

Nutramax

(4)
From
$438.00
$350.40 Save 20% on 1st Autoship, 5% off future orders
SAMeLQ 425 Chewable Tablets SAMeLQ 425 Chewable Tablets

SAMeLQ 425 Chewable Tablets

Ceva

(7)
From
$621.00
$496.80 Save 20% on 1st Autoship, 5% off future orders
Denamarin Denamarin

Nutramax Denamarin Liver Health Supplement for Large Dogs - With S-Adenosylmethionine (SAMe) and Silybin, Tablets

Nutramax

From
$598.00
$478.40 Save 20% on 1st Autoship, 5% off future orders
Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs With S-Adenosylmethionine (SAMe) - Dog Supplements & Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs With S-Adenosylmethionine (SAMe) - Dog Supplements &

Nutramax Denosyl Liver and Brain Health Supplement for Medium Dogs, With S-Adenosylmethionine (SAMe)

Nutramax

(1)
From
$255.00
$204.00 Save 20% on 1st Autoship, 5% off future orders
Denamarin Medium 225mg Denamarin Medium 225mg

Nutramax Denamarin Liver Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe) and Silybin, Tablets

Nutramax

(1)
From
$351.00
$280.80 Save 20% on 1st Autoship, 5% off future orders
Rx Vitamins CoQ10 Supplement For Dogs and Cats (30 softgels) Rx Vitamins CoQ10 Supplement For Dogs and Cats (30 softgels)

Rx Vitamins CoQ10 Supplement For Dogs and Cats (30 softgels)

Rx Vitamins

(1)
$172.00
$137.60 Save 20% on 1st Autoship, 5% off future orders
denamarin for cats and small dogs denamarin tablets

Nutramax Denamarin Liver Health Supplement for Small Dogs and Cats - With S-Adenosylmethionine (SAMe) and Silybin

Nutramax

(2)
From
$263.00
$210.40 Save 20% on 1st Autoship, 5% off future orders
Nutramax Denosyl Liver and Brain Health Supplement for Small Dogs and Cats With S-Adenosylmethionine (SAMe) - 1 pack Nutramax Denosyl Liver and Brain Health Supplement for Small Dogs and Cats With S-Adenosylmethionine (SAMe) - Dog

Nutramax Denosyl Liver and Brain Health Supplement for Small Dogs and Cats, With S-Adenosylmethionine (SAMe)

Nutramax

(2)
From
$191.00
$152.80 Save 20% on 1st Autoship, 5% off future orders
Denamarin for Cats and Small Dogs in a Bottle - Dog Supplements & Vitamins 1 Denamarin for Cats and Small Dogs in a Bottle - Dog Supplements & Vitamins 2

Denamarin for Cats and Small Dogs in a Bottle

Nutramax

(1)
From
$271.00
$216.80 Save 20% on 1st Autoship, 5% off future orders
Omega Healthy Heart Capsules for Cats and Dogs Omega Healthy Heart Capsules for Cats and Dogs

Omega Healthy Heart Capsules for Cats and Dogs

VetriScience

(1)
$250.00
$200.00 Save 20% on 1st Autoship, 5% off future orders
Nutramax Denamarin Liver Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe) and Silybin - 1 bottle Nutramax Denamarin Liver Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe) and Silybin - Dog

Nutramax Denamarin Liver Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe) and Silybin

Nutramax

(1)
From
$359.00
$287.20 Save 20% on 1st Autoship, 5% off future orders
CoQ10 Healthy Heart Capsules for Dogs and Cats CoQ10 Healthy Heart Capsules for Dogs and Cats

CoQ10 Healthy Heart Capsules for Dogs and Cats

VetriScience

$108.00
$86.40 Save 20% on 1st Autoship, 5% off future orders
SAMeLQ 100 chewable tablets bottles for pet health SAMeLQ 100 Chewable Tablets bottle for pet health

SAMeLQ 100 Chewable Tablets for Dogs & Cats - Boost Liver Health

Ceva

From
$279.00
$223.20 Save 20% on 1st Autoship, 5% off future orders
VetriScience Vetri Liver Supplement for Dogs (60 soft chews) - Dog Supplements & Vitamins 1 VetriScience Vetri Liver Supplement for Dogs (60 soft chews) - Dog Supplements & Vitamins 2

VetriScience Vetri Liver Supplement for Dogs (60 soft chews)

VetriScience

(1)
$316.00
$252.80 Save 20% on 1st Autoship, 5% off future orders
Rx Vitamins Hepato Support Liver Supplement - 180 caps - Dog Supplements & Vitamins 1 Rx Vitamins Hepato Support Liver Supplement - Dog Supplements & Vitamins 2

Rx Vitamins Hepato Support Liver Supplement

Rx Vitamins

(2)
From
$223.00
$178.40 Save 20% on 1st Autoship, 5% off future orders
SAMe Liver Health 225 mg tablet for Dogs SAMe Liver Health 225 mg tablet for Dogs

SAMe Liver Health 225 mg tablet for Dogs

VetriScience

(1)
$271.00
$216.80 Save 20% on 1st Autoship, 5% off future orders
S-Adenosy-L Methionine for Dogs and Cats also come in a 60ct bottle. This pet liver health supplement comes in a chewable tablet making it easy to administer SAMeLQ 225mg for dogs and cats provide liver support. SAMeLQ tablets are available in 100, 225, and 425mg. These chewable liver tablets for pets are also flavored making administration even easier

SAMeLQ S-Adenosyl-L Methionine 225 Chewable Tablets

Ceva

From
$373.00
$298.40 Save 20% on 1st Autoship, 5% off future orders
standard process canine cardiac support standard process heart supplements

Standard Process Canine Cardiac Support- Heart Supplement for Dogs

Standard Process

(1)
From
$168.00
$134.40 Save 20% on 1st Autoship, 5% off future orders
SAMe Liver Health 90 mg Tablet for Cats and Dogs SAMe Liver Health 90 mg Tablet for Cats and Dogs

SAMe Liver Health 90 mg Tablet for Cats and Dogs

VetriScience

$160.00
$128.00 Save 20% on 1st Autoship, 5% off future orders
Extra Strength Healthy Heart Chews for Dogs Extra Strength Healthy Heart Chews for Dogs

Extra Strength Healthy Heart Chews for Dogs

VetriScience

(1)
$250.00
$200.00 Save 20% on 1st Autoship, 5% off future orders
standard process canine hepatic support standard process canine hepatic support

Standard Process Canine Hepatic Support- Liver Metabolism Support for Dogs

Standard Process

From
$199.00
$159.20 Save 20% on 1st Autoship, 5% off future orders
Rx Vitamins Formula CV For Dogs and Cats (90 caps) - Cat Supplements & Vitamins 1 Rx Vitamins Formula CV For Dogs and Cats (90 caps) - Cat Supplements & Vitamins 2

Rx Vitamins Formula CV For Dogs and Cats (90 caps)

Rx Vitamins

$263.00
$210.40 Save 20% on 1st Autoship, 5% off future orders

Shop Dog Heart & Liver Supplements for a Long & Active Life

Support your dog’s most vital organs with HardyPaw’s expertly curated collection of dog heart and liver supplements, formulated to enhance cardiovascular performance, boost liver function, and promote overall vitality. From aging pets to breed-prone conditions, our science-backed solutions help your dog stay active, energetic, and healthy for years to come.

Why Is Dog Heart & Liver Health Support Important?

The heart and liver are central to your dog’s energy, metabolism, detoxification, and longevity. Unfortunately, dogs can develop cardiovascular or hepatic (liver-related) issues due to aging, genetics, medications, obesity, or environmental toxins. That's why HardyPaw provides targeted nutritional support through premium supplements designed to maintain organ health at every life stage.

Our vet-recommended products help:

  • Support Heart Muscle Function: Improve energy efficiency and oxygen transport.
  • Maintain Normal Blood Pressure and Rhythm: Promote balanced cardiovascular output.
  • Enhance Liver Detoxification: Support bile production, enzyme regulation, and toxin elimination.
  • Combat Oxidative Damage: Provide antioxidant protection from cellular stress.

What Heart & Liver Support Supplements Does HardyPaw Offer?

We carry condition-specific and combination supplements to support both heart and liver health:

Liver Support Supplements for Dogs:

Heart Support Supplements for Dogs:

  • VetriScience Cardio Strength: Combines L-carnitine, CoQ10, taurine, and antioxidants to promote cardiac muscle integrity and blood flow.
  • VetriScience CoQ10 10mg: Supports mitochondrial energy and cardiovascular function.
  • Rx Vitamins CoQ10: High-potency softgels to enhance antioxidant support for the heart.
  • O3 Omega Capsules: Contains EPA and DHA, essential fatty acids that promote healthy heart rhythm and reduce inflammation.

How Can You Proactively Support Your Dog’s Heart and Liver Health?

Veterinarians recommend a proactive care plan that includes:

  • Regular Checkups: Detect issues early through bloodwork, X-rays, and ultrasounds.
  • Weight Control: Obesity contributes to both hepatic and cardiac stress.
  • Heart-Healthy, Hepatic-Friendly Diets: Choose low-sodium and liver-supportive nutrition.
  • Medication Monitoring: Some drugs stress the liver—supplements can provide support alongside vet oversight.
  • Supplementation: Use vet-approved supplements for ongoing nutritional support.

What to Consider Before Using Dog Heart & Liver Supplements?

  • Veterinary Supervision: Always consult your vet before starting a new supplement.
  • Breed & Age-Specific Needs: Seniors and large breeds often need extra support.
  • Supplement Interactions: Check for interactions with existing medications or diets.
  • Supplement Form: Choose between chews, capsules, tablets, or softgels based on ease of administration.
  • Consistency & Patience: Organ support supplements often show benefits over time with consistent use.

Why Trust HardyPaw for Dog Heart & Liver Support?

  • Vet-Approved Products: Every supplement is backed by veterinary science and real results.
  • Trusted Brands: From Denamarin to VetriScience, we carry only the most reliable options.
  • Tailored Solutions: We have supplements for dogs of all sizes, breeds, and life stages.
  • Transparent Pricing: Competitive and honest pricing across all premium formulations.
  • Reliable Support: Have questions? Our knowledgeable team is here to help you make informed decisions.

Dog Heart & Liver Supplements FAQs 

What’s the difference between Denamarin and Denosyl for dogs?

Denamarin combines SAMe and Silybin for both liver detox and regeneration, making it a more comprehensive option.Denosyl contains only SAMe, ideal when antioxidant support alone is needed.

Can I crush liver or heart supplements if my dog won't take pills?

Most tablets should not be crushed as it may affect absorption. Consider switching toDenamarin Chewable Tablets orSAMeLQ Chewables, which offer palatable, easy-to-administer formats.

Is CoQ10 safe to combine with liver supplements for dogs?

Yes, CoQ10 supports heart energy metabolism and is safe to pair with liver formulas. Use a vet-approved option likeRx Vitamins CoQ10 orVetriScience CoQ10 for safe integration.

Are there breed-specific considerations when choosing liver or heart supplements?

Yes, large breeds like Dobermans or Labradors may benefit fromDenamarin for Large Dogs orVetriScience Cardio Strength due to increased cardiovascular and hepatic strain.

How can I tell if my dog's supplement is working?

Monitor for improved energy, appetite, coat quality, and normal lab results. Products likeDenamarin andSAMeLQ show benefits within weeks but require vet checkups for measurable outcomes.