{"product_id":"spironolactone-hydrochlorothiazide-generic-tablets-25-mg","title":"Spironolactone \/ Hydrochlorothiazide Tablets, 25mg","description":"\u003cp\u003e\u003cimg loading=\"lazy\" data-files=\"rx-map.jpg\" data-original=\"https:\/\/shopify-images-bucket.s3.us-west-2.amazonaws.com\/rx-map.jpg\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/rx-map.webp\" class=\"img-responsive\" alt=\"RX MAP\" width=\"700\"\u003e\u003c\/p\u003e\n\u003ch2\u003eCombination Diuretic Tablets for Heart Failure and Fluid Retention in Pets\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eSpironolactone and Hydrochlorothiazide 25mg Tablets are a prescription combination diuretic used by veterinarians to treat \u003ca href=\"\/en-gb\/collections\/heart-blood-pressure\" title=\"Heart \u0026amp; blood pressure medications for dogs \u0026amp; cats – enalapril, cardalis | hardypaw\" aria-label=\"Heart \u0026amp; blood pressure medications for dogs \u0026amp; cats – enalapril, cardalis | hardypaw\"\u003econgestive heart failure\u003c\/a\u003e and fluid retention in dogs and cats. Spironolactone holds onto potassium while clearing excess fluid, while hydrochlorothiazide pushes sodium and fluid out through the kidneys. The two together are often the go-to when pets stop responding to other diuretics, and they also help manage abdominal fluid buildup from liver disease.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCongestive Heart Failure Treatment:\u003c\/strong\u003e Clears excess fluid and salt from the body to take the pressure off pets dealing with congestive heart failure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePotassium-Sparing Combination:\u003c\/strong\u003e Spironolactone keeps potassium levels stable when hydrochlorothiazide and other diuretics would otherwise deplete them during treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAscites Management:\u003c\/strong\u003e Helps reduce abdominal fluid buildup caused by liver failure or other underlying conditions in dogs and cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Pressure Reduction:\u003c\/strong\u003e Works alongside other cardiac medications to bring blood pressure down and offer some protection to the heart muscle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRefractory Edema Support:\u003c\/strong\u003e A practical option for pets whose fluid retention has not improved on other diuretics used in standard treatment plans.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eSpironolactone 25mg, Hydrochlorothiazide 25mg\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eSpironolactone \/ Hydrochlorothiazide 25mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking this tablet into a soft pill pocket or pill wrap treat is a simple way to get your pet to take their dose without any fuss. Pairing it with a small amount of food is also a good idea to help keep stomach discomfort at bay.\u003c\/p\u003e\n\u003cp\u003e\u003ca aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" href=\"\/en-gb\/collections\/dog-pill-pockets\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" href=\"\/en-gb\/collections\/cat-pill-pockets\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Kidney Failure:\u003c\/strong\u003e Pets with anuria, acute kidney insufficiency, or serious kidney impairment should not be started on this medication.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Hyperkalemia:\u003c\/strong\u003e Pets already running high on blood potassium should not receive this medication, as spironolactone may push those levels even higher.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Addison's Disease:\u003c\/strong\u003e Pets with Addison's disease should not be given this medication due to the serious electrolyte complications it can trigger.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Liver Disease:\u003c\/strong\u003e Pets with liver disease need close monitoring on this medication, even though it is also used to treat ascites in liver failure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWear Gloves When Handling:\u003c\/strong\u003e Spironolactone is listed as a hazardous drug by NIOSH, so gloves should be worn when handling, particularly during pregnancy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDrug Interaction Risk:\u003c\/strong\u003e Share a full list of your pet's current medications, including ACE inhibitors, NSAIDs, digoxin, insulin, and potassium supplements, with your veterinarian before starting.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegular Bloodwork Required:\u003c\/strong\u003e Keeping tabs on electrolyte levels and kidney function through routine blood tests is an important part of staying on top of your pet's health during treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eElectrolyte Imbalances:\u003c\/strong\u003e Shifts in potassium or sodium levels are among the more commonly seen reactions and tend to improve once the medication is stopped.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDehydration Signs:\u003c\/strong\u003e Unusual thirst, less urination, weakness, tiredness, dizziness, and muscle cramps can all point to dehydration that needs veterinary attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Upset:\u003c\/strong\u003e Vomiting, diarrhea, and a drop in appetite can come up, more so at higher doses or when treatment is just getting started.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFacial Dermatitis in Cats:\u003c\/strong\u003e Itchy skin sores on the face are a serious reaction seen mostly in Maine Coon cats and need immediate veterinary attention.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reactions:\u003c\/strong\u003e Labored breathing, a rash, fever, or swelling around the face may be signs of an allergic reaction that needs prompt veterinary care.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eStore at Room Temperature:\u003c\/strong\u003e Keep tablets at or below 77°F inside a childproof, light-resistant container away from heat and moisture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect From Light:\u003c\/strong\u003e A light-resistant container helps both active ingredients hold their potency and stay stable over time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOut of Reach:\u003c\/strong\u003e Keep this medication somewhere children and untreated animals in the home cannot get to it.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNOTE:\u003c\/strong\u003e\u003c\/span\u003e For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca aria-label=\"Shipping policy | hardypaw\" title=\"Shipping policy | hardypaw\" href=\"\/en-gb\/pages\/shipping-policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca aria-label=\"Refund policy\" title=\"Refund policy\" href=\"\/en-gb\/policies\/refund-policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What conditions do spironolactone and hydrochlorothiazide tablets treat in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This combination is prescribed for congestive heart failure, fluid retention, high blood pressure, and ascites from liver disease in dogs and cats. It tends to be the next step when pets have not responded well enough to other diuretics as part of their cardiac care plan.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why is spironolactone considered a potassium-sparing diuretic for pets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Spironolactone targets aldosterone receptors in the kidneys, which lets the body hang onto potassium instead of flushing it out. This pairs well with hydrochlorothiazide, which tends to pull potassium out of the body and can lead to significant depletion without something to counterbalance it.\u003c\/p\u003e\n\u003ch3\u003eQ3: Are there any special handling precautions for spironolactone tablets?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Spironolactone is flagged as a hazardous drug by NIOSH, so wearing gloves when handling the tablets is important, especially for anyone who is pregnant. If skin contact happens accidentally, washing the area well with water is recommended. Keep the medication away from children and other animals at all times.\u003c\/p\u003e\n\u003ch3\u003eQ4: What are the signs of a serious reaction to this medication in cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Maine Coon cats in particular can develop itchy, sore skin lesions on the face, which is a serious and uncommon reaction to watch out for. Facial swelling, labored breathing, vomiting, or a sudden drop in drinking and urinating are also warning signs that need immediate veterinary attention.\u003c\/p\u003e\n\u003ch3\u003eQ5: What regular monitoring is needed while a pet is on this medication?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Routine blood tests to check potassium, sodium, and kidney function are an important part of keeping pets safe on this medication. Blood pressure should also be tracked regularly. When the dose is first started or changed, a veterinarian may want to run tests more often to stay on top of any shifts.\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 tablet","offer_id":43564882002081,"sku":"478574-1","price":1.0,"currency_code":"GBP","in_stock":true},{"title":"100 tablets","offer_id":43564882034849,"sku":"478574","price":54.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/spironolactone-hydrochlorothiazide-tablets-25mg-pet-medication-209.png?v=1778538355","url":"https:\/\/hordypaw.shop\/en-gb\/products\/spironolactone-hydrochlorothiazide-generic-tablets-25-mg","provider":"HardyPaw","version":"1.0","type":"link"}