{"product_id":"mirtazapine-tablets-15-mg","title":"Mirtazapine Tablets, 15 mg","description":"\u003ch2\u003ePrescription Appetite Stimulant Tablets for Sick Dogs and Cats\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eMirtazapine 15mg Tablets are a prescription medication that veterinarians use primarily as an appetite stimulant and anti-nausea aid in dogs and cats dealing with chronic illness. Although it was originally developed as an antidepressant, its ability to boost appetite and settle nausea is what makes it genuinely useful in veterinary practice. It is commonly prescribed for pets with kidney disease, inflammatory bowel disease, liver disease, and cancer-related inappetence, as well as those struggling with chemotherapy-associated nausea. Your vet will determine the right dosing schedule for your pet's species and condition.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAppetite Stimulation in Chronic Illness:\u003c\/strong\u003e Reliably increases food intake in dogs and cats with illness-related anorexia from kidney disease, IBD, liver disease, and cancer.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntiemetic Properties:\u003c\/strong\u003e Blocks serotonin and histamine receptors involved in the vomiting reflex, reducing nausea signals from the gut and brain simultaneously.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemotherapy Nausea and Appetite Support:\u003c\/strong\u003e Helps ease nausea and bring appetite back in pets going through cancer chemotherapy treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioral Applications:\u003c\/strong\u003e Used off-label for separation anxiety in dogs and urine spraying and interstitial cystitis-related stress in cats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGI Prokinetic Effect:\u003c\/strong\u003e Improves gastric emptying and colonic motility in dogs, providing additional gastrointestinal management benefits alongside appetite stimulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eMirtazapine 15mg\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eMirtazapine 15mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.\u003c\/p\u003e\n\u003cp\u003ePlease follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.\u003c\/p\u003e\n\u003cp\u003eTucking it inside a soft pill pocket or wrapping it in a pill wrap treat is one of the easiest ways to make the whole process stress-free.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/en-gb\/collections\/dog-pill-pockets\" title=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\" aria-label=\"Dog pill pockets \u0026amp; wraps: best easy pill-giving solutions | hardypaw\"\u003eShop Pill Pockets for Dogs\u003c\/a\u003e | \u003ca href=\"\/en-gb\/collections\/cat-pill-pockets\" title=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\" aria-label=\"Cat pill pockets \u0026amp; wraps: easy medication treats | hardypaw\"\u003eShop Pill Pockets for Cats\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid With MAOIs:\u003c\/strong\u003e Do not use within at least 14 days of selegiline, amitraz-containing flea collars, linezolid, or any monoamine oxidase inhibitor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid With Cyproheptadine:\u003c\/strong\u003e Do not combine with cyproheptadine, as it directly works against mirtazapine's effects and will significantly reduce how well the medication performs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerotonin Syndrome Risk:\u003c\/strong\u003e Combining with SSRIs, trazodone, tramadol, or other serotonergic drugs without close veterinary oversight carries a real risk of serotonin syndrome.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Heart Disease:\u003c\/strong\u003e Use carefully in pets with pre-existing cardiac conditions or significant blood pressure changes, as mirtazapine can influence heart rate and pressure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaution in Kidney and Liver Disease:\u003c\/strong\u003e Pets with hepatic or renal impairment need careful management on this medication, as reduced organ function affects how the drug is cleared.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid in Pregnancy:\u003c\/strong\u003e Safety in pregnant, lactating, or breeding animals has not been established; use only under direct veterinary guidance in these cases.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCheck for Drug Interactions:\u003c\/strong\u003e Before starting treatment, make sure your vet knows if your pet is currently on clonidine, diazepam, tramadol, amitraz, selegiline, or fluvoxamine.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Appetite:\u003c\/strong\u003e Appetite stimulation is the primary intended effect in veterinary use and is expected and desirable in most treatment contexts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSedation and Behavioral Changes:\u003c\/strong\u003e Drowsiness, altered behaviour, and shifts in activity level are commonly reported, particularly when first starting treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVocalization in Cats:\u003c\/strong\u003e Unusual howling and increased vocalisation are well-documented and commonly reported reactions in cats receiving mirtazapine.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eElevated Liver Enzymes in Cats:\u003c\/strong\u003e Some cats develop raised liver enzyme values during treatment, making periodic bloodwork an important part of ongoing monitoring.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSerotonin Syndrome Signs:\u003c\/strong\u003e Tremors, agitation, vocalisation, panting, vomiting, rapid heart rate, and incoordination point to a serious reaction needing immediate emergency veterinary care.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eRoom Temperature Storage:\u003c\/strong\u003e Store tablets in a tightly closed container away from heat and humidity, keeping conditions stable and consistent between doses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect from Moisture and Heat:\u003c\/strong\u003e A dark, dry storage location away from direct sunlight is the best way to keep these tablets at their full strength.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Out of Reach:\u003c\/strong\u003e Always store this medication somewhere secure and out of reach of children and untreated pets.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003eNote: \u003c\/strong\u003e\u003c\/span\u003eFor generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.\u003c\/p\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-gb\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-gb\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What conditions does mirtazapine treat in dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Mirtazapine is most often used to tackle poor appetite and nausea in pets dealing with kidney disease, IBD, liver disease, cancer, or chemotherapy side effects. It also has off-label uses for separation anxiety in dogs and stress-related conditions in cats. Your vet will confirm whether it is the right choice for your pet's situation.\u003c\/p\u003e\n\u003ch3\u003eQ2: Why is the dosing frequency different for dogs and cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cats hold onto mirtazapine in their system considerably longer than dogs do, which means they need it less often to maintain a consistent effect. Giving a cat the same frequency as a dog risks the medication building up to levels that increase the chance of side effects. Your vet will set the schedule that is right for your pet's species and individual response.\u003c\/p\u003e\n\u003ch3\u003eQ3: Why does mirtazapine cause vocalization in cats?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cats on mirtazapine quite commonly start howling or vocalising more than usual, particularly in the hours after a dose. The exact reason is not fully understood, but it is tied to how the medication interacts with certain receptor systems in the feline brain. It tends to ease off as drug levels drop, but if it is severe or prolonged, your vet is worth consulting.\u003c\/p\u003e\n\u003ch3\u003eQ4: Why should mirtazapine never be combined with cyproheptadine?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Cyproheptadine works on the exact same receptors that mirtazapine relies on to stimulate appetite and reduce nausea, so giving both together essentially undoes what mirtazapine is trying to achieve. The two cancel each other out rather than complement one another. Interestingly, this is also why cyproheptadine is sometimes used as an emergency countermeasure when mirtazapine has been given in excess.\u003c\/p\u003e\n\u003ch3\u003eQ5: What are the signs of mirtazapine overdose in cats and dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e A pet that has had too much mirtazapine may show tremors, agitation, excessive vocalisation, panting, vomiting, a racing heart rate, or poor coordination. These are signs that something serious is going on and the situation needs veterinary attention straight away. Do not wait to see whether things settle on their own before reaching out to your vet or an emergency clinic.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.nhs.uk\/medicines\/mirtazapine\/about-mirtazapine\/\" title=\"About mirtazapine - nhs\" aria-label=\"Visit a webpage about About mirtazapine - nhs\"\u003ehttps:\/\/www.nhs.uk\/medicines\/mirtazapine\/about-mirtazapine\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a697009.html\" title=\"Mirtazapine: medlineplus drug information\" aria-label=\"Visit a webpage about Mirtazapine: medlineplus drug information\"\u003ehttps:\/\/medlineplus.gov\/druginfo\/meds\/a697009.html\u003c\/a\u003e\u003c\/p\u003e","brand":"Varies (Generic)","offers":[{"title":"1 tablet","offer_id":41799706345633,"sku":"268971-1","price":1.0,"currency_code":"GBP","in_stock":true},{"title":"30 tablets","offer_id":41799706312865,"sku":"268971","price":4.0,"currency_code":"GBP","in_stock":true},{"title":"60 tablets","offer_id":44422401654945,"sku":"268971-60","price":7.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/mirtazapine-tablets-15-mg-pet-medicine-745.png?v=1778505622","url":"https:\/\/hordypaw.shop\/en-gb\/products\/mirtazapine-tablets-15-mg","provider":"HardyPaw","version":"1.0","type":"link"}