{"product_id":"palladia-tablets-for-dogs-10mg","title":"Palladia Tablets for Dogs (Toceranib Phosphate) 10mg, 30 tablets","description":"\u003ch2\u003e\u003cstrong\u003eTargeted Mast Cell Tumor Treatment for Dogs\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003ePALLADIA is a prescription oral cancer therapy authorized by the FDA for dogs diagnosed with returning skin mast cell tumors graded II or III under the Patnaik system, regardless of whether the condition has spread to the lymph nodes. The active ingredient, toceranib phosphate, works by focusing on the pathways that help tumors grow. It also helps cut off the blood supply that cancer cells need to survive. When used under a veterinarian’s guidance, this targeted treatment can lead to a measurable response in tumor control.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargeted Cancer Therapy:\u003c\/strong\u003e Selectively inhibits receptor tyrosine kinases involved in tumor growth and angiogenesis in canine mast cell tumors.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDual Mechanism Action:\u003c\/strong\u003e Helps slow the growth of tumor cells while also limiting the formation of new blood vessels that feed the tumor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProven Clinical Response:\u003c\/strong\u003e In controlled studies, it showed a much higher response rate compared to a placebo.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOral Administration:\u003c\/strong\u003e Comes in a tablet form that is typically given every other day, as directed by a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdjustable Dosing Protocol:\u003c\/strong\u003e Allows dose reductions or temporary interruptions to help manage treatment-related adverse effects.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eVariants\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e10 mg tablets\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ca\/products\/palladia-tablets-for-dogs-15mg\" title=\"15 mg tablets\" aria-label=\"15 mg tablets\"\u003e15 mg tablets\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en-ca\/products\/palladia-tablets-for-dogs-50-mg\" title=\"50 mg tablets\" aria-label=\"50 mg tablets\"\u003e50 mg tablets\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eComposition Table\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 38.4699%; height: 104px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 59.9417%; height: 35.5966px;\" width=\"264\"\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.7811%; height: 35.5966px;\" width=\"175\"\u003e\n\u003cp\u003e\u003cstrong\u003eQuantity per Tablet\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 59.9417%; height: 35.5966px;\" width=\"264\"\u003e\n\u003cp\u003eToceranib (as toceranib phosphate)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.7811%; height: 35.5966px;\" width=\"175\"\u003e\n\u003cp\u003e10 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 59.9417%; height: 35.5966px;\" width=\"264\"\u003e\n\u003cp\u003eToceranib (as toceranib phosphate)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.7811%; height: 35.5966px;\" width=\"175\"\u003e\n\u003cp\u003e15 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 59.9417%; height: 35.5966px;\" width=\"264\"\u003e\n\u003cp\u003eToceranib (as toceranib phosphate)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 39.7811%; height: 35.5966px;\" width=\"175\"\u003e\n\u003cp\u003e50 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003eRecommended-Dosage Chart\u003c\/strong\u003e\u003c\/h4\u003e\n\u003ctable style=\"width: 38.1137%; height: 669px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 55.1989px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 55.1989px;\" width=\"135\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight (lb)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 55.1989px;\" width=\"130\"\u003e\n\u003cp\u003e\u003cstrong\u003eDose (Every Other Day)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 55.1989px;\" width=\"138\"\u003e\n\u003cp\u003e\u003cstrong\u003eDog Body Weight (lb)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 55.1989px;\" width=\"126\"\u003e\n\u003cp\u003e\u003cstrong\u003eDose (Every Other Day)\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e11.0 – 11.8 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e15 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e76.4 – 79.6 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e115 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e11.9 – 15.2 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e20 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e79.7 – 84.7 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e120 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e15.3 – 18.5 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e25 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e84.8 – 94.8 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e130 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e18.6 – 22.0 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e30 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e94.9 – 105.0 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e150 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e22.1 – 25.4 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e35 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e105.1 – 110.0 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e160 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e25.5 – 28.7 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e40 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e110.1 – 113.5 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e165 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e28.8 – 32.2 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e45 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e113.6 – 118.6 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e170 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e32.3 – 35.5 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e50 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e118.7 – 128.8 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e180 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e35.6 – 38.8 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e55 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e128.9 – 138.9 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e200 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e38.9 – 42.3 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e60 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e139.0 – 144.0 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e210 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e42.4 – 45.6 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e65 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e144.1 – 157.6 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e215 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e45.7 – 50.7 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e70 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e157.7 – 173.1 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e250 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e50.8 – 59.3 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e80 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e173.2 – 177.9 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e260 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e59.4 – 65.9 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e95 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e178.0 – 191.6 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e265 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e66.0 – 71.2 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e100 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e191.7 – 220.5 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e300 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 35.5966px;\"\u003e\n\u003ctd style=\"width: 25.2007%; height: 35.5966px;\" width=\"135\"\u003e\n\u003cp\u003e71.3 – 76.3 lb\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 24.3007%; height: 35.5966px;\" width=\"130\"\u003e\n\u003cp\u003e110 mg\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 25.7407%; height: 35.5966px;\" width=\"138\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 23.5807%; height: 35.5966px;\" width=\"126\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eInitial recommended dose is 3.25 mg\/kg orally every other day. Dose adjustments may be required.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eDosage \u0026amp; Administration Instructions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Only:\u003c\/strong\u003e Under federal regulations, this medication may only be administered by a licensed veterinarian or provided with a veterinarian’s prescription or authorization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInitial Dose:\u003c\/strong\u003e Give 3.25 mg per kg of body weight by mouth every other day, or exactly as your veterinarian instructs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDose Adjustments:\u003c\/strong\u003e If side effects occur, your vet may lower the dose by 0.5 mg per kg or pause treatment for a period of time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDo Not Split:\u003c\/strong\u003e Do not cut or break the tablets. They need to stay intact to keep the protective coating effective.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFood Flexibility:\u003c\/strong\u003e May be administered with or without food according to veterinary recommendation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eAdditional Information\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cstrong\u003ePrecautions\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Restriction:\u003c\/strong\u003e Do not use in breeding dogs or in pregnant or lactating bitches.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVascular Risk:\u003c\/strong\u003e This medication can affect blood vessels and may lead to swelling or blood clots. If this happens, treatment should be stopped right away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGI Monitoring:\u003c\/strong\u003e If there are signs of stomach ulcers or severe bleeding during treatment, the medication should be discontinued.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory Monitoring:\u003c\/strong\u003e Regular checkups with your veterinarian are important. Blood tests will be needed to keep an eye on neutrophils, albumin, creatinine, and hematocrit levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCYP3A4 Interaction:\u003c\/strong\u003e Use extra care when giving this drug alongside strong CYP3A4 inhibitors, as they can raise the levels of toceranib in the body.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003ePossible Side Effects\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Effects:\u003c\/strong\u003e Diarrhea, vomiting, anorexia, and blood in stool are commonly reported reactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWeight Loss:\u003c\/strong\u003e Significant body weight reduction has been observed during treatment phases.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeutropenia Risk:\u003c\/strong\u003e Decreased neutrophil counts may occur and require dose modification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLameness Episodes:\u003c\/strong\u003e Dose-related lameness and musculoskeletal discomfort have been reported.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGI Perforation:\u003c\/strong\u003e Rare but serious gastrointestinal perforations and hemorrhage have occurred.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cstrong\u003eStorage Information\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eControlled Temperature:\u003c\/strong\u003e Store at 20° to 25° C or 68° to 77° F.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSecure Storage:\u003c\/strong\u003e Keep tablets in a secure location out of reach of children.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOriginal Packaging:\u003c\/strong\u003e Keep tablets in the original container to maintain integrity and safety.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e\u003cstrong\u003eShipping \u0026amp; Return\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, priority, and international delivery; see our \u003ca href=\"\/en-ca\/pages\/shipping-policy\" title=\"Shipping policy\" aria-label=\"Shipping policy\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ca\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE. \u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cstrong\u003eQ1: What is PALLADIA used for in dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PALLADIA is indicated for the treatment of recurrent Patnaik grade II or III cutaneous mast cell tumors in dogs, with or without regional lymph node involvement. It is prescribed by veterinarians as part of a cancer treatment plan when measurable disease is present after surgery.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ2: How does PALLADIA work against mast cell tumors?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PALLADIA contains toceranib phosphate, a receptor tyrosine kinase inhibitor that blocks signaling pathways involved in tumor cell growth and angiogenesis. It inhibits targets such as KIT, VEGFR2, and PDGFR, helping reduce tumor proliferation and blood vessel formation, supporting cancer progression.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ3: How often should PALLADIA be given to dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e The initial suggested dosage is 3.25 milligrams per kilogram of the dog’s body weight, given by mouth on an every other day schedule. Dose reductions or temporary treatment interruptions may be required depending on laboratory findings or adverse reactions, as determined through regular veterinary monitoring.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ4: What are the most common side effects of PALLADIA?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Commonly reported side effects include diarrhea, vomiting, decreased appetite, lethargy, lameness, weight loss, and blood in the stool. Laboratory abnormalities such as neutropenia and hypoalbuminemia have also been observed. Veterinary monitoring is essential during treatment.\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eQ5: Is PALLADIA safe for pregnant or breeding dogs?\u003c\/strong\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e PALLADIA should not be used in breeding dogs or in pregnant or lactating bitches. Because it inhibits angiogenesis, it may harm developing fetuses and is expected to cause adverse effects during pregnancy. Use only under direct veterinary supervision.\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"Default Title","offer_id":41253128306849,"sku":"10003313","price":379.0,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/palladia-tablets-for-dogs-toceranib-phosphate-10mg-30-pet-medicine-969.jpg?v=1778103726","url":"https:\/\/hordypaw.shop\/en-ca\/products\/palladia-tablets-for-dogs-10mg","provider":"HardyPaw","version":"1.0","type":"link"}