{"product_id":"apoquel-tablets-for-dogs-5-4mg","title":"Apoquel (oclacitinib) Tablets, 5.4 mg","description":"\u003ch2\u003eApoquel 5.4mg Tablet for Fast Allergy Itch and Skin Inflammation Relief in Dogs\u003c\/h2\u003e\n\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eApoquel (oclacitinib maleate) 5.4 mg is a prescription oral tablet formulated to control itching and skin inflammation in dogs caused by allergic and atopic dermatitis. As a synthetic Janus Kinase (JAK) inhibitor that works by targeting the specific cytokines responsible for triggering allergic itch and inflammation in dogs, rather than acting through steroids or antihistamines. It gets to work within 4 hours, with most dogs experiencing meaningful itch relief within 24 hours, and it is safe enough for both short-term and ongoing use in dogs aged 12 months and above.\u003c\/p\u003e\n\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRapid Itch Relief:\u003c\/strong\u003e Allergic itch starts being brought under control within 4 hours of the first dose, putting a quick stop to scratching, licking, and chewing.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eEffective Within 24 Hours:\u003c\/strong\u003e Most dogs see strong itch relief within a single day, bringing real comfort to those dealing with allergic skin conditions.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eTargets the Root Cause:\u003c\/strong\u003e Directly blocks the Janus Kinase 1 (JAK1) and JAK3 cytokine pathways that set off allergic itch and inflammation, rather than simply masking the symptoms.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNot a Steroid or Antihistamine:\u003c\/strong\u003e Oclacitinib is a unique immunomodulator that controls itch through a different mechanism, avoiding the drawbacks of corticosteroids and antihistamines.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eShort and Long-Term Use:\u003c\/strong\u003e Approved for both short-term relief and ongoing maintenance therapy, making it a flexible option for managing chronic allergic dermatitis year-round.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eCompatible with Common Medications:\u003c\/strong\u003e Works well in combination with parasiticides, antibiotics, vaccines, and allergen-specific immunotherapy based on observed clinical experience.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eClinically Proven Effectiveness:\u003c\/strong\u003e In a 30-day trial, 86.4% of treated dogs had meaningfully lower itch scores by the end of just one week.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eActive Ingredients\u003c\/h4\u003e\n\u003cp\u003eOclacitinib maleate 5.4 mg per tablet\u003c\/p\u003e\n\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDosage \u0026amp; Administration Instructions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e Apoquel is federally restricted to use by or on the order of a licensed veterinarian; always obtain a valid prescription before purchasing or administering.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eInitial Dosing Phase:\u003c\/strong\u003e Administer orally twice daily for up to 14 days at the recommended dose of 0.18 to 0.27 mg oclacitinib per lb (0.4 to 0.6 mg\/kg) body weight.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eMaintenance Dosing:\u003c\/strong\u003e After the initial 14-day period, reduce to once daily administration for ongoing long-term management of allergic or atopic dermatitis.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eWeight-Based Tablet Count:\u003c\/strong\u003e For dogs weighing 10 to 14.9 lbs, give half a 5.4 mg tablet; for dogs weighing 20 to 29.9 lbs, give one 5.4 mg tablet; for dogs weighing 45 to 59.9 lbs, give two 5.4 mg tablets.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eWith or Without Food:\u003c\/strong\u003e Giving Apoquel with a meal or on an empty stomach makes no real difference to how well it absorbs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eRegular Monitoring Required:\u003c\/strong\u003e Dogs receiving Apoquel should be monitored periodically by a veterinarian for the development of infections and any new growths or lumps.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eWash Hands After Handling:\u003c\/strong\u003e Always wash hands immediately after handling Apoquel tablets; in case of accidental eye contact, flush with water or saline for at least 15 minutes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.\u003c\/p\u003e\n\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNot for Dogs Under 12 Months:\u003c\/strong\u003e Apoquel is approved only for use in dogs 12 months of age and older; do not administer to puppies or younger dogs.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAvoid in Active Infections:\u003c\/strong\u003e Do not use Apoquel in dogs with serious or active infections, as it modulates the immune system and may worsen existing infectious conditions.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNeoplasia Risk Consideration:\u003c\/strong\u003e New benign and malignant neoplastic conditions have been observed in clinical studies; consider risks and benefits carefully in dogs with a history of recurring neoplasia.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNot Evaluated with Immunosuppressants:\u003c\/strong\u003e The combined use of Apoquel with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents has not been evaluated and should be avoided.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eBreeding, Pregnant, or Lactating Dogs:\u003c\/strong\u003e Apoquel is not approved for use in breeding dogs or in pregnant or nursing female dogs under any circumstances.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSecure Storage from Pets:\u003c\/strong\u003e Keep Apoquel in a location completely inaccessible to dogs, cats, and other animals to prevent accidental ingestion or overdose.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eVomiting:\u003c\/strong\u003e Among the most commonly reported adverse reactions in clinical trials; typically mild in nature and tended to resolve on its own with continued dosing.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDiarrhea:\u003c\/strong\u003e Loose stools were reported in a small percentage of dogs during both short-term and long-term Apoquel clinical studies.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eLethargy and Anorexia:\u003c\/strong\u003e Temporary tiredness and reduced appetite have been reported in some dogs receiving Apoquel; most cases resolved without stopping treatment.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIncreased Susceptibility to Infection:\u003c\/strong\u003e Apoquel may raise the risk of infections including demodicosis and pyoderma due to its immune-modulating mechanism of action.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eNew Lumps or Growths:\u003c\/strong\u003e Cutaneous or subcutaneous lumps, including histiocytomas and lipomas, were noted in some dogs during clinical studies; always have new lumps evaluated promptly.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eChanges in Blood Parameters:\u003c\/strong\u003e Mild decreases in white blood cell counts and increases in cholesterol and lipase were observed; group means remained within normal reference ranges during studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n  \u003cli\u003e\n\u003cstrong\u003eIdeal Storage Temperature:\u003c\/strong\u003e Keep Apoquel tablets somewhere dry and stable, within a temperature range of 68°F(20°C) - 77°F(25°C) to preserve their potency.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eKeep in Original Packaging:\u003c\/strong\u003e Holding onto the original container is the best way to shield tablets from moisture and keep them fresh throughout use.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eAway from All Pets and Children:\u003c\/strong\u003e Keep Apoquel and all veterinary medications completely out of reach of animals and children at all times.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ca\/pages\/shipping-policy\" target=\"_blank\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ca\/policies\/refund-policy\" target=\"_blank\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\n\u003ch3\u003eQ1: What is Apoquel oclacitinib 5.4mg tablet used for in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Apoquel 5.4 mg is a vet-prescribed oral tablet for dogs aged 12 months and above that helps keep allergic and atopic dermatitis-related itching under control. Rather than masking the discomfort, it goes straight to the source by blocking the Janus Kinase (JAK) cytokine pathways that trigger allergic itch in the first place.\u003c\/p\u003e\n\n\u003ch3\u003eQ2: How quickly does Apoquel allergy tablet start working in dogs?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Apoquel begins controlling allergic itch within 4 hours of the first dose and achieves effective itch relief within 24 hours. In a clinical study, over 86% of treated dogs showed a significant reduction in owner-assessed itching scores within one week of starting treatment.\u003c\/p\u003e\n\n\u003ch3\u003eQ3: Is Apoquel oclacitinib tablet safe to use with other pet medications?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Apoquel has been used safely with many commonly prescribed medications including parasiticides, antibiotics, vaccines, and allergen-specific immunotherapy. However, its combined use with glucocorticoids, cyclosporine, or other immunosuppressants has not been evaluated and should be discussed with your veterinarian.\u003c\/p\u003e\n\n\u003ch3\u003eQ4: Can Apoquel anti-itch tablet be given to dogs long-term?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Yes. Apoquel is approved for both short-term relief and long-term maintenance use in dogs 12 months of age and older. Dogs on ongoing therapy should be periodically monitored by a veterinarian for any signs of infection, new skin growths, or other changes in health.\u003c\/p\u003e\n\n\u003ch3\u003eQ5: What types of dog allergies can Apoquel oclacitinib treat?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Apoquel covers a broad range of allergic skin conditions in dogs, from atopic dermatitis and flea, food, or contact allergies to other forms of allergic dermatitis, helping bring both itch and inflammation under control across all these conditions with clinical studies to back it up.\u003c\/p\u003e\n\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35300697\/\" target=\"_blank\" rel=\"noopener\" title=\"Acceptance of oclacitinib maleate (apoquel®) chewable tablets in client-owned dogs with allergic and atopic dermatitis - pubmed\" aria-label=\"Visit a webpage about Acceptance of oclacitinib maleate (apoquel®) chewable tablets in client-owned dogs with allergic and atopic dermatitis - pubmed\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/35300697\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/idp.springer.com\/transit?redirect_uri=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1186%2Fs12917-022-03210-x%3F\u0026amp;code=c0bb306c-d956-41f2-90f9-2cb2453543f9\" target=\"_blank\" rel=\"noopener\" title=\"Https:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-022-03210-x\" aria-label=\"Visit a webpage about Https:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-022-03210-x\"\u003ehttps:\/\/bmcvetres.biomedcentral.com\/articles\/10.1186\/s12917-022-03210-x\u003c\/a\u003e\u003c\/p\u003e","brand":"Zoetis","offers":[{"title":"250 Tablets","offer_id":43651129147553,"sku":"10022316","price":1141.0,"currency_code":"CAD","in_stock":true},{"title":"100 Tablets","offer_id":41231780216993,"sku":"10022316-100","price":457.0,"currency_code":"CAD","in_stock":true},{"title":"60 Tablets","offer_id":43651129114785,"sku":"10022316-60","price":274.0,"currency_code":"CAD","in_stock":true},{"title":"30 Tablets","offer_id":43651129082017,"sku":"10022316-30","price":137.0,"currency_code":"CAD","in_stock":true},{"title":"1 Tablet","offer_id":41231780151457,"sku":"10022316-1","price":5.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/apoquel-oclacitinib-tablets-5-4-mg-250-pet-medicine-284.jpg?v=1777914624","url":"https:\/\/hordypaw.shop\/en-ca\/products\/apoquel-tablets-for-dogs-5-4mg","provider":"HardyPaw","version":"1.0","type":"link"}