{"product_id":"advantage-multi-topical-solution-for-dogs-20-1-55-lbs","title":"Advantage Multi Topical Solution for Dogs 20.1-55 lbs, Red","description":"\u003ch2\u003eMonthly Topical 6-in-1 Parasite Protection for Medium Dogs (20.1–55 lbs)\u003c\/h2\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eAdvantage Multi Topical Solution (Red) is a prescription, once-monthly spot-on treatment for dogs and puppies weighing between 20.1 and 55 pounds. Each tube pairs Imidacloprid (10%) with Moxidectin (2.5%) to tackle six different parasites in a single monthly application. It covers heartworm prevention, adult flea control, sarcoptic mange, and intestinal worm treatment all at once. Dogs and puppies from 7 weeks old and at least 3 pounds are eligible for treatment.\u003c\/p\u003e\n\u003ch3\u003eBenefits\u003c\/h3\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm Disease Prevention:\u003c\/strong\u003e Moxidectin is absorbed into the body and steadily works against heartworm larvae (Dirofilaria immitis) throughout the entire month.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Circulating Microfilariae:\u003c\/strong\u003e One of the few products indicated to reduce circulating Dirofilaria immitis microfilariae in dogs already carrying a heartworm infection.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKills Adult Fleas:\u003c\/strong\u003e Imidacloprid travels through the skin's natural lipid layer, reaching and killing adult fleas before they ever get a chance to bite.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevents Flea Infestations:\u003c\/strong\u003e Re-infesting fleas are killed within 3 to 5 minutes of contact, stopping them from settling in and laying eggs on your dog.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Sarcoptic Mange:\u003c\/strong\u003e Provides reliable control of sarcoptic mange caused by Sarcoptes scabiei var. canis, commonly picked up at dog parks, grooming salons, or boarding facilities.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Roundworms:\u003c\/strong\u003e Works against adult Toxocara canis and Toxascaris leonina roundworm infections in medium dogs with every monthly application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Hookworms:\u003c\/strong\u003e Addresses Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala hookworm infections across multiple life stages.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTreats Whipworms:\u003c\/strong\u003e Rounds out intestinal parasite coverage by controlling Trichuris vulpis whipworm infections alongside all other targeted parasites.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWater-Resistant Formula:\u003c\/strong\u003e Heartworm protection holds up 60 minutes after swimming and 90 minutes after a bath, keeping active medium dogs covered.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose Flexibility:\u003c\/strong\u003e A dose missed by a few days can be applied right away, with the regular monthly schedule continuing from that point.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEarly Puppy Use:\u003c\/strong\u003e This product can be used on puppies that have reached 7 weeks of age and a body weight of at least 3 pounds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003ch4\u003eComposition Table\u003c\/h4\u003e\n\u003ctable style=\"width: 59.664%; height: 14px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 24.6607%; height: 19.6023px;\"\u003e\u003cstrong\u003eIngredient\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75.0621%; height: 19.6023px;\"\u003e\u003cstrong\u003eQuantity (per tube, 20.1–55 lb dogs)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 24.6607%; height: 19.6023px;\"\u003eImidacloprid\u003c\/td\u003e\n\u003ctd style=\"width: 75.0621%; height: 19.6023px;\"\u003e250 mg (10%)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6023px;\"\u003e\n\u003ctd style=\"width: 24.6607%; height: 19.6023px;\"\u003eMoxidectin\u003c\/td\u003e\n\u003ctd style=\"width: 75.0621%; height: 19.6023px;\"\u003e62.5 mg (2.5%)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eTotal volume: 2.5 mL\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003ch4\u003eDirections for Use\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrescription Required:\u003c\/strong\u003e This FDA-licensed spot-on must be dispensed through or under the direction of a licensed veterinarian.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMonthly Application:\u003c\/strong\u003e Empty the full contents of one tube onto your dog's skin once a month, ideally keeping to the same date each time.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimum Dose:\u003c\/strong\u003e Each monthly application should deliver at least 4.5 mg\/lb (10 mg\/kg) imidacloprid and 1.1 mg\/lb (2.5 mg\/kg) moxidectin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 1 – Open the Tube:\u003c\/strong\u003e Take one applicator tube out of the pack. Keep it upright and pull the cap off.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg loading=\"lazy\" data-files=\"advantage-multi-dog-how-to-use.jpg\" data-original=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/advantage-multi-dog-how-to-use.jpg?v=1722240405\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/advantage-multi-dog-how-to-use.jpg\" alt=\"Advantage Multi Topical Solution for Dogs 20.1-55 lbs Red\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 2 – Break the Seal:\u003c\/strong\u003e Flip the cap around, press it back onto the tube tip, and give it a twist to open the seal. Remove the cap fully before applying.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 3 – Prepare the Application Site:\u003c\/strong\u003e Ask your dog to stand still. Part the fur along the back between the shoulder blades until the skin underneath is clearly visible.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStep 4 – Apply the Solution at Multiple Spots:\u003c\/strong\u003e Rest the tip directly on the skin and squeeze the contents out across three or four spots along the backline, starting from the base of the neck and moving toward the upper back. Pick spots your dog cannot reach to lick. Avoid putting too much product in one place to prevent run-off.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003e\u003cimg loading=\"lazy\" data-files=\"advantage-multi-dog-application_65691c61-6177-462c-90fe-25201a789034.jpg\" data-original=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/advantage-multi-dog-application_65691c61-6177-462c-90fe-25201a789034.jpg?v=1722240437\" src=\"https:\/\/hordypaw.shop\/cdn\/shop\/files\/advantage-multi-dog-application_65691c61-6177-462c-90fe-25201a789034.jpg\" alt=\"Advantage Multi Topical Solution for Dogs 20.1-55 lbs Red\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eAvoid Irritated Skin:\u003c\/strong\u003e Do not apply the solution to any area of skin that looks broken, sore, or inflamed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSarcoptic Mange Dosing:\u003c\/strong\u003e A single topical application is the standard for mange treatment; a follow-up dose the next month may be considered if your vet recommends it.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMissed Dose:\u003c\/strong\u003e Apply the missed dose straight away and carry on with the regular monthly schedule without doubling up the next time.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any medication for your pet.\u003c\/p\u003e\n\u003ch3\u003eAdditional Information\u003c\/h3\u003e\n\u003ch4\u003ePrecautions\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeartworm Screening First:\u003c\/strong\u003e A vet-administered heartworm check should be completed before the first dose, as adult heartworm infections already present are not addressed by this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for Adult Heartworms:\u003c\/strong\u003e This product has no effect on adult heartworms; dogs confirmed as positive should complete adulticide treatment before starting this product.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNever Give by Mouth:\u003c\/strong\u003e Swallowing this product can trigger serious reactions including tremors, loss of coordination, drooling, and dilated pupils; it must only ever be applied to the skin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrevent Post-Application Licking:\u003c\/strong\u003e For at least 30 minutes after applying, keep your dog away from the treated spot and away from any other treated animals nearby.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKeep Children Clear:\u003c\/strong\u003e Children should not touch or go near the treated area on your dog's skin for a full two hours following each application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDogs Only:\u003c\/strong\u003e This formulation must not be used on cats; a separate product designed specifically for feline use is available.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtect the Eyes:\u003c\/strong\u003e Should the product make contact with your dog's eyes, hold the eyelids open, flush thoroughly with clean water, and contact your vet without delay.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge and Weight Limits:\u003c\/strong\u003e This product has not been proven safe for puppies younger than 7 weeks or those weighing under 3 pounds; avoid use below these thresholds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnwell or Weak Dogs:\u003c\/strong\u003e Take extra care with dogs that are sick, recovering, or noticeably underweight; speak to your vet before going ahead with treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBreeding Females:\u003c\/strong\u003e Safety in pregnant or lactating dogs has not been confirmed; always check with your vet before treating breeding females.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdulticide Timing:\u003c\/strong\u003e This product has not been assessed for safety when given on the same day as heartworm adulticide therapy; your vet should determine the right timing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicrofilariae Monitoring:\u003c\/strong\u003e In a small number of heartworm-positive dogs, microfilariae counts may stay the same or rise after treatment; regular veterinary follow-up is important.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWash Hands Promptly:\u003c\/strong\u003e Wash your hands thoroughly with soap and water straight after handling or applying this product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003ePossible Side Effects\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Reactions at Site:\u003c\/strong\u003e Mild itching, skin thickening, or slight residue at the application area may appear but typically clears up on its own without treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStomach Upset:\u003c\/strong\u003e Some dogs may experience loose stools, vomiting, a drop in appetite, or blood in the stool; let your vet know if any of these occur.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLow Energy:\u003c\/strong\u003e A temporary dip in energy or longer sleep periods has been noted in some dogs after their monthly application.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBehavioural Changes:\u003c\/strong\u003e Restlessness, over-grooming, hiding, or pacing after application are possible; contact your vet if the behaviour does not settle within a day.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIngestion Reactions:\u003c\/strong\u003e If swallowed through licking, the product can lead to muscle tremors, unsteady movement, and breathing changes; seek emergency veterinary help right away.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Infection:\u003c\/strong\u003e Localised skin infection (pyoderma) at or around the application site was observed in some dogs during field safety assessments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAllergic Reaction:\u003c\/strong\u003e Though uncommon, facial swelling, hives, very pale gums, or collapse require urgent veterinary attention and should not be left unaddressed.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExcessive Drooling:\u003c\/strong\u003e A rise in saliva production within the first hour after application has been reported; flag this to your vet if it does not pass quickly.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage Information\u003c\/h4\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003e\n\u003cstrong\u003eCorrect Temperature Range:\u003c\/strong\u003e Keep stored between 39°F (4°C) and 77°F (25°C), away from direct heat and out of freezing conditions at all times.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSafe Storage Practice:\u003c\/strong\u003e Store this prescription product well out of reach of children and other household animals to prevent any accidental contact or ingestion.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eShipping \u0026amp; Return\u003c\/h3\u003e\n\u003cp\u003eWe offer ground, express, and priority delivery; see our \u003ca href=\"\/en-ca\/pages\/shipping-policy\" title=\"Shipping policy | hardypaw\" aria-label=\"Shipping policy | hardypaw\"\u003eshipping policy\u003c\/a\u003e for details.\u003c\/p\u003e\n\u003cp\u003eFor return instructions or product concerns, please refer to our detailed \u003ca href=\"\/en-ca\/policies\/refund-policy\" title=\"Refund policy\" aria-label=\"Refund policy\"\u003erefund policy\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003ch3\u003eQ1: What parasites does Advantage Multi (Red) protect medium dogs against?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Advantage Multi (Red) covers six parasites in one monthly application: heartworm larvae, circulating microfilariae in infected dogs, adult fleas, flea infestations, sarcoptic mange mites, and intestinal worms covering roundworms, hookworms, and whipworms. Tick prevention is not included.\u003c\/p\u003e\n\u003ch3\u003eQ2: How does the Red Box application differ from the smaller Green and Teal variants?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e For dogs up to 20 lbs, the full tube is applied at one spot between the shoulder blades. The Red Box for 20.1 to 55 lb dogs requires the 2.5 mL contents spread across three or four spots along the backline for even distribution. Never apply too much at a single point.\u003c\/p\u003e\n\u003ch3\u003eQ3: How does Advantage Multi (Red) stand apart from oral heartworm preventives?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This spot-on absorbs through the skin and sustains protection all month without a daily tablet. It also brings flea control, mange treatment, and intestinal worm coverage into one application, and is one of the few products that can reduce circulating microfilariae in dogs already infected with heartworm.\u003c\/p\u003e\n\u003ch3\u003eQ4: What should I do if my medium dog licks the application site?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e Swallowing this product can bring on muscle tremors, unsteady movement, dilated pupils, and heavy drooling. Take your dog to a vet or emergency clinic without delay if licking happens. After applying, keep your dog away from the treated spot and separate it from other pets for at least 30 minutes.\u003c\/p\u003e\n\u003ch3\u003eQ5: Can Advantage Multi (Red) be used if my dog already has heartworms?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAns:\u003c\/strong\u003e This product cannot clear adult heartworms from the body. Dogs confirmed with heartworm disease should go through adulticide treatment first. It is, however, indicated to lower circulating microfilariae counts in infected dogs. Your vet should always guide the timing to keep treatment safe.\u003c\/p\u003e\n\u003ch2\u003eClinical Research\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a\" title=\"Dailymed - advantage multi for dogs- imidacloprid, moxidectin solution\" aria-label=\"Visit a webpage about Dailymed - advantage multi for dogs- imidacloprid, moxidectin solution\"\u003ehttps:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=3fc1a42b-6576-4890-aa0c-5c0eb903c85a\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/804\" title=\"Https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadfoi\/804\" aria-label=\"Visit a webpage about Https:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadfoi\/804\"\u003ehttps:\/\/animaldrugsatfda.fda.gov\/adafda\/app\/search\/public\/document\/downloadFoi\/804\u003c\/a\u003e\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"1 month","offer_id":44249772359841,"sku":"90209559-1","price":34.0,"currency_code":"CAD","in_stock":true},{"title":"6 months","offer_id":44249772392609,"sku":"90209559","price":203.0,"currency_code":"CAD","in_stock":true},{"title":"12 months","offer_id":44249772425377,"sku":"90209559-PK2","price":405.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0593\/2446\/5313\/files\/advantage-multi-topical-solution-for-dogs-20-1-55-lbs-red-6-months-679.jpg?v=1778102094","url":"https:\/\/hordypaw.shop\/en-ca\/products\/advantage-multi-topical-solution-for-dogs-20-1-55-lbs","provider":"HardyPaw","version":"1.0","type":"link"}